United States Government Publishing Office publisher pbl distributor dst United States Commerce Department National Institute of Standards and Technology (NIST) author aut Government Organization Duewer, David L. author aut text government publication eng GOVPUB Executive Agency Publications executive 2023-12-14 Commerce Department 2022-09-21 monographic deposited born digital 79 digital object pages C 13. https://www.govinfo.gov/app/details/GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a P0b002ee1c308687b on1389890330 (OCoLC)1389890330 DGPO 2023-12-14 2026-06-27 GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a machine generated eng fdlp C13 GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a dbf771eb89e70f2b49d13941dba13b9a GOVPUB NIST Interagency or Internal Reports NOTE: THE “DATE ISSUED” ABOVE MAY DEFAULT TO JANUARY 1ST OF A GIVEN YEAR. TO THE VIEW THE MOST ACCURATE DATE OF ISSUE, REVIEW THE TITLE PAGE OF THE PUBLICATION. Interim or final reports on work performed by NIST for outside sponsors (both government and non-government). May also report results of NIST projects of transitory or limited interest, including those that will be published subsequently in more comprehensive form. National Institute of Standards and Technology Commerce Department. National Institute of Standards and Technology. 2022 2022-09-21 https://www.govinfo.gov/app/details/GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a https://www.govinfo.gov/content/pkg/GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a/pdf/GOVPUB-C13-dbf771eb89e70f2b49d13941dba13b9a.pdf Performance History of the Fat-Soluble Vitamin-Related Studies Apparent precision Carotenoids Concordance Human serum Interlaboratory measurement reproducibility functions Liquid-frozen samples Lyophilized samples Micronutrients Measurement Quality Assurance Program (MMQAP) Robust scale estimators SRM 968 Ubiquinones Vitamin A Vitamin E Standard reference materials Duewer, David L. creator Duewer, David L. Kline, Margaret C. May, Willie E. Sharpless, Katherine E. Thomas, Jeanice B. National Institute of Standards and Technology (U.S.) Material Measurement Laboratory mdu U.S. Dept. of Commerce, National Institute of Standards and Technology 2022-09-21. monographic 1 online resource (79 pages) : illustrations (color) text technical report eng From 1984 to 2017, the National Institute of Standards and Technology (NIST) Micronutrients Measurement Quality Assurance Program (MMQAP) coordinated 79 Round Robin (RR) interlaboratory studies designed to improve measurement comparability among laboratories measuring fat soluble vitamins and carotenoids in human serum and plasma. There were 22 participants in the initial study; participation increased to 58 in 1997 and then declined in stages to 29 by 2017. A total of 138 academic, commercial, governmental, or non-governmental organizations actively participated in at least one RR; two laboratories participated in 77 of the 79 RRs. A total of 350 human serum or plasma samples were distributed in the RRs, typically three to five per RR. One hundred thirty one (131) of these samples were unique materials. While the initial RRs focused on just retinol (vitamin A), ? tocopherol (vitamin E), and ? carotene (provitamin A) over the life of the program 57 vitamin related measurands were reported at least once. Fifteen (15) measurands were reported sufficiently often to enable analysis of measurement performance over time: total retinol, retinyl palmitate, ? tocopherol, ? plus ? tocopherol, total ? carotene, trans ? carotene, total cis ? carotene, total ? carotene, total lycopene, trans lycopene, total ? cryptoxanthin, total lutein, total zeaxanthin, total lutein plus zeaxanthin, and coenzyme Q10. In addition to documenting the number and nature of the MMQAP's participants, measurands, materials, and reported measurements, this report explores the evolution of among-participant concordance and within-participant apparent precision as functions of calendar date documents and the relationships among results reported for materials delivered to participants both as liquid-frozen and lyophilized samples. David L. Duewer; Margaret C. Kline; Willie E. May; Katherine E. Sharpless; Jeanice B. Thomas. September 2022. Title from PDF title page (viewed January 4, 2023). Includes bibliographical references. Approved by the NIST Editorial Review Board on 2022-09-20 Mode of access: World Wide Web. Systems requirements: Adobe Acrobat PDF reader. Standard reference materials Carotenoids Ubiquinones Vitamin A Vitamin E Apparent precision Concordance Human serum Interlaboratory measurement reproducibility functions Liquid-frozen samples Lyophilized samples Micronutrients Measurement Quality Assurance Program (MMQAP) SRM 968 Robust scale estimators https://doi.org/10.6028/NIST.IR.7880-50 performance history of the fat-soluble vitamin-related studies performance history of the fat-soluble vitamin-related studies