United States Government Publishing Office publisher pbl distributor dst United States Commerce Department National Institute of Standards and Technology (NIST) author aut Government Organization Place, Benjamin J. author aut text government publication eng GOVPUB Executive Agency Publications executive 2023-10-27 Commerce Department 2021-07-30 monographic deposited born digital 14 digital object pages C 13. https://www.govinfo.gov/app/details/GOVPUB-C13-903e13eb59d451d547606cc697d959f6 P0b002ee1c1bb3780 on1389890048 (OCoLC)1389890048 DGPO 2023-10-27 2026-06-27 GOVPUB-C13-903e13eb59d451d547606cc697d959f6 machine generated eng fdlp C13 GOVPUB-C13-903e13eb59d451d547606cc697d959f6 903e13eb59d451d547606cc697d959f6 GOVPUB NIST Interagency or Internal Reports NOTE: THE “DATE ISSUED” ABOVE MAY DEFAULT TO JANUARY 1ST OF A GIVEN YEAR. TO THE VIEW THE MOST ACCURATE DATE OF ISSUE, REVIEW THE TITLE PAGE OF THE PUBLICATION. Interim or final reports on work performed by NIST for outside sponsors (both government and non-government). May also report results of NIST projects of transitory or limited interest, including those that will be published subsequently in more comprehensive form. National Institute of Standards and Technology Commerce Department. National Institute of Standards and Technology. 2021 2021-07-30 https://www.govinfo.gov/app/details/GOVPUB-C13-903e13eb59d451d547606cc697d959f6 https://www.govinfo.gov/content/pkg/GOVPUB-C13-903e13eb59d451d547606cc697d959f6/pdf/GOVPUB-C13-903e13eb59d451d547606cc697d959f6.pdf Interlaboratory Study 1 Results Chemistry Environmental analysis Non-targeted analysis Place, Benjamin J. creator Place, Benjamin J. Rimmer, Catherine A. National Institute of Standards and Technology (U.S.) Material Measurement Laboratory mdu U.S. Dept. of Commerce, National Institute of Standards and Technology 2021-07-30. monographic 1 online resource (14 pages) : illustrations (color) text technical report eng Non-targeted analysis is the determination of the chemical composition of a complex mixture without a priori knowledge regarding the identities or quantities of the compound. These techniques can be performed in a wide variety of materials and areas of study. Methods and results between laboratories can vary widely based on the compounds of interest and user expertise, which can cause poor interlaboratory comparability of non-targeted results. To address this knowledge gap, three research grade test materials were developed to allow for the comparison of instrument methods, specifically reversed-phase liquid chromatography with positive electrospray ionization mass spectrometry. The materials were shipped to thirty-one participating laboratories to be analyzed by their own non-targeted analysis instrumental method. Of the participants, twenty-three laboratories submitted good quality datasets and could be further evaluated. Using principal components analysis, the differences and similarities of the analytical methods could be examined. Overall, there were no obvious trends or associations between the methods of different laboratories and the review of the principal components analysis revealed no notable parameters that caused significant clustering or separation. Benjamin J. Place; Catherine A. Rimmer. July 2021. Title from PDF title page (viewed October 1, 2021). Includes bibliographical references. Approved by the NIST Editorial Review Board on 2021-07-16 Mode of access: World Wide Web. Systems requirements: Adobe Acrobat PDF reader. Chemistry Non-targeted analysis Environmental analysis https://doi.org/10.6028/NIST.IR.8384 interlaboratory study 1 results interlaboratory study 1 results