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 <subject>Animal diseases</subject>
 <subject>Biocontainment laboratories</subject>
 <subject>Biological research</subject>
 <subject>Data integrity</subject>
 <subject>Disease control</subject>
 <subject>Disease detection or diagnosis</subject>
 <subject>Disease surveillance</subject>
 <subject>Facility security</subject>
 <subject>Federal facility relocation</subject>
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 <subject>ARS Plum Island Animal Disease Center</subject>
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 <title>High-Containment Biosafety Laboratories: DHS Lacks Evidence to Conclude That Foot-and-Mouth Disease Research Can Be Done Safely on the U.S. Mainland</title>
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<abstract>DHS is proposing to move foot-and mouth disease (FMD) research
from its current location at the Plum Island Animal Disease	 
Center--located on a federally owned island off the northern tip 
of Long Island, New York--and potentially onto the United States 
mainland. FMD is the most highly infectious animal disease that  
is known. Nearly 100 percent of exposed animals become infected. 
A single outbreak of FMD on the U.S. mainland could have	 
significant economic consequences. Concerns have been raised	 
about moving FMD research off its island location and onto the	 
U.S. mainland--where it would be in closer proximity to 	 
susceptible animal populations--as opposed to building a new	 
facility on the island. GAO was asked to evaluate the evidence	 
DHS used to support its decision that FMD work can be done safely
on the U.S. mainland, whether an island location provides any	 
additional protection over and above that provided by modern high
containment laboratories on the mainland, and the economic	 
consequences of an FMD outbreak on the U.S. mainland. In	 
preparing this testimony, GAO interviewed officials from DHS and 
USDA, talked with experts in FMD and high-containment		 
laboratories worldwide, and reviewed studies on FMD,		 
high-containment laboratories, and the economic consequences of  
FMD outbreaks. GAO also visited the Plum Island Animal Disease	 
Center and other animal biocontainment laboratories in other	 
countries.</abstract>
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 <topic>Animal diseases</topic>
 <topic>Biocontainment laboratories</topic>
 <topic>Biological research</topic>
 <topic>Data integrity</topic>
 <topic>Disease control</topic>
 <topic>Disease detection or diagnosis</topic>
 <topic>Disease surveillance</topic>
 <topic>Facility security</topic>
 <topic>Federal facility relocation</topic>
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 <topic>Infectious diseases</topic>
 <topic>Research and development facilities</topic>
 <topic>Research program management</topic>
 <topic>Research programs</topic>
 <topic>Risk assessment</topic>
 <topic>Risk factors</topic>
 <topic>Risk management</topic>
 <topic>Safety standards</topic>
 <topic>Site selection</topic>
 <topic>Zoonotic diseases</topic>
 <topic>ARS Plum Island Animal Disease Center</topic>
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  <title>United States Statutes at Large</title>
  <partNumber>Volume 116 Page 2135</partNumber>
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  <title>United States Public Law 296 (107th Congress)</title>
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