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<abstract>Some of the Environmental Protection Agency&apos;s (EPA) regulations set
standards that limit environmental contaminants to levels that are
determined, in large part, on the basis of the health risks they pose.
However, when EPA assesses the health risks of contaminants, the agency
is faced with uncertainties and gaps in scientific knowledge and data.
This report summarizes GAO&apos;s findings on whether EPA&apos;s benefits
estimates for major environmental regulations that establish
health-based standards reflect precautionary assumptions about health
risks. Three key factors influence EPA&apos;s use of precautionary
assumptions in assessing health risks. First, EPA is influenced by its
mission to protect human health and safeguard the natural environment.
Second, EPA is influenced by the nature and extent of relevant data.
Finally, EPA is influenced by the nature of the health risk being
evaluated.</abstract>
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