Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke; Established List Additions and Request for Comments

United States Government Publishing Office publisher pbl distributor dst United States National Archives and Records Administration Office of the Federal Register author aut Government Organization text government publication eng FR Regulatory Information 2026_register executive 2026-04-23 article Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke; Established List Additions and Request for Comments Notices D09002ee1e0c7ed4f D09002ee1e0c7edd0 United States Department of Health and Human Services originator org United States Government Agency or Subagency United States Food and Drug Administration originator org United States Government Agency or Subagency The Food and Drug Administration (FDA, the Agency, or we) is adding constituents to the list of harmful and potentially harmful constituents (HPHCs) in tobacco products and tobacco smoke (the established HPHC list) as required by the Federal Food, Drug, and Cosmetic Act (the FD&C Act). 91 FR 21824 https://www.govinfo.gov/app/details/FR-2026-04-23/2026-07910 2026-07910 fr23ap26-55 4164-01-P Docket No. FDA-2026-N-2642 https://www.govinfo.gov/app/details/FR-2026-04-23/2026-07910 https://www.govinfo.gov/content/pkg/FR-2026-04-23/html/2026-07910.htm https://www.govinfo.gov/content/pkg/FR-2026-04-23/pdf/2026-07910.pdf 6 p. 21824 21829 91 FR 21824 Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke; Established List Additions and Request for Comments; Federal Register Vol. 91, Issue NOTICE 2026-07910 DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 2026-05-26 Docket No. FDA-2026-N-2642 4164-01-P 2026-07910 Notice; established list additions and request for comments.

The Food and Drug Administration (FDA, the Agency, or we) is adding constituents to the list of harmful and potentially harmful constituents (HPHCs) in tobacco products and tobacco smoke (the established HPHC list) as required by the Federal Food, Drug, and Cosmetic Act (the FD&C Act).

Either electronic or written comments on the notice must be submitted by May 26, 2026. Anna Julia Adams or Matthew Brenner, Center for Tobacco Products, Food and Drug Administration, Document Control Center, Bldg. 71, Rm. G335, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002; 1-877-287-1373, CTPRegulations@fda.hhs.gov. Established List Additions Harmful and Potentially Harmful Constituents in Tobacco Products and Tobacco Smoke, CTPRegulations@fda.hhs.gov https://www.fda.gov/media/80109/download https://www.govinfo.gov/content/pkg/FR-2015-09-18/pdf/2015-23389.pdf https://www.regulations.gov Federal Register Vol. 91, no. 78 Office of the Federal Register, National Archives and Records Administration 2026-04-23 continuing daily deposited born digital 234 p. Table of Contents: AE 2.7: GS 4.107: AE 2.106: KF70.A2 https://www.govinfo.gov/app/details/FR-2026-04-23 P0b002ee1e0c6c404 0097-6326 0042-1219 0364-1406 769-004-00000-9 000582072 f:fr23ap26 https://www.govinfo.gov/app/details/FR-2026-04-23 https://www.govinfo.gov/content/pkg/FR-2026-04-23/pdf/FR-2026-04-23.pdf https://www.govinfo.gov/content/pkg/FR-2026-04-23/xml/FR-2026-04-23.xml fdlp 21713 21936 DGPO 2026-04-23 2026-04-23 FR-2026-04-23 machine generated eng FR FR-2026-04-23 91 78