United States Government Publishing Office publisher pbl distributor dst United States National Archives and Records Administration Office of the Federal Register author aut Government Organization text government publication eng FR Regulatory Information 2025_register executive 2025-06-12 article Rules and Regulations D09002ee1d3eb611b D09002ee1d3eb619e United States Environmental Protection Agency originator org United States Government Agency or Subagency EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination. 90 FR 24977 https://www.govinfo.gov/app/details/FR-2025-06-13/2025-10812 2025-10812 fr13jn25-10 RIN 2070-AB27 6560-50-P EPA-HQ-OPPT-2023-0328 FRL-11825-02-OCSPP https://www.govinfo.gov/app/details/FR-2025-06-13/2025-10812 https://www.govinfo.gov/content/pkg/FR-2025-06-13/html/2025-10812.htm https://www.govinfo.gov/content/pkg/FR-2025-06-13/pdf/2025-10812.pdf Chemicals Hazardous Substances Environmental Protection Reporting and Recordkeeping Requirements 18 p. 24977 24994 90 FR 24977 Title 40 Part 721 40 CFR Part 721 Title 40 Part 9 40 CFR Part 9 RIN 2070-AB27 Significant New Use Rules on Certain Chemical Substances (23-3.5e); Federal Register Vol. 90, Issue RULE 2025-10812 ENVIRONMENTAL PROTECTION AGENCY 2025-08-12 EPA-HQ-OPPT-2023-0328 FRL-11825-02-OCSPP 6560-50-P 2025-10812 Final rule.

EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

This rule is effective on August 12, 2025. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on June 27, 2025. For technical information contact: Punam Tyagi, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, Chemicals Hazardous Substances Environmental Protection Reporting and Recordkeeping Requirements Significant New Use Rules on Certain Chemical Substances (233.5e), TSCA-Hotline@epa.gov tyagi.punam@epa.gov wysong.william@epa.gov https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce https://www.epa.gov/dockets https://www.epa.gov/laws-regulations-and-executive-orders https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca https://www.epa.gov/tsca-import-export-requirements https://www.epa.gov/tsca-inventory https://www.regulations.gov Vol. 90, no. 113 Office of the Federal Register, National Archives and Records Administration 2025-06-13 continuing daily deposited born digital 177 p. Table of Contents: AE 2.7: GS 4.107: AE 2.106: KF70.A2 https://www.govinfo.gov/app/details/FR-2025-06-13 P0b002ee1d3eabf5d 0097-6326 0042-1219 0364-1406 769-004-00000-9 000582072 f:fr13jn25 https://www.govinfo.gov/app/details/FR-2025-06-13 https://www.govinfo.gov/content/pkg/FR-2025-06-13/pdf/FR-2025-06-13.pdf https://www.govinfo.gov/content/pkg/FR-2025-06-13/xml/FR-2025-06-13.xml fdlp 24955 25121 DGPO 2025-06-12 2025-06-13 FR-2025-06-13 machine generated eng FR FR-2025-06-13 90 113