United States Government Publishing Office publisher pbl distributor dst United States National Archives and Records Administration Office of the Federal Register author aut Government Organization text government publication eng FR Regulatory Information 2007_register executive 2010-09-22 article Rules and Regulations D09002ee1c809d162 D09002ee1c809d210 United States Department of Justice originator org United States Government Agency or Subagency United States Drug Enforcement Administration originator org United States Government Agency or Subagency On May 25, 2006, DEA published a Notice of Proposed Rulemaking which proposed the addition of a specific definition for the term "positional isomer" to allow for the systematic determination of which isomers of schedule I substances would be considered to be "positional," and therefore, subject to schedule I control. This rulemaking finalizes that definition. The Controlled Substances Act (CSA) and its implementing regulations specify which hallucinogenic substances are considered schedule I controlled substances. The CSA states that all salts, isomers, and salts of isomers of these substances are also schedule I controlled substances. In non-technical terms, an isomer of a substance is a different compound, but a compound which has the same number and kind of atoms. The terms "optical isomer" and "geometric isomer" are specific scientific terms and it is easy to determine whether one substance is an optical or geometric isomer of another. The term "positional isomer," however, is subject to scientific interpretation. The addition of a definition for the term "positional isomer" will assist legitimate research[ers] and industry in determining the control status of materials that are "positional isomers" of schedule I hallucinogens. While the DEA will remain the authority for ultimately determining the control status of a given material, providing a specific definition for "positional isomer" will ensure consistent criteria are utilized in making these determinations. This rule does not change existing laws, regulations, policies, processes, and procedures regarding the determination of control status for schedule I hallucinogenic substances. This rule merely makes available to the public the longstanding definition of "positional isomer" which DEA has used when making these scheduling determinations. This rule is relevant only to specialized forensic or research chemists. Most of these individuals are existing DEA registrants who are authorized by the DEA to handle schedule I hallucinogenic substances. 72 FR 67850 https://www.govinfo.gov/app/details/FR-2007-12-03/E7-23413 E7-23413 fr03de07-6 RIN 1117-AA94 4410-09-P Docket No. DEA-260F https://www.govinfo.gov/app/details/FR-2007-12-03/E7-23413 https://www.govinfo.gov/content/pkg/FR-2007-12-03/html/E7-23413.htm https://www.govinfo.gov/content/pkg/FR-2007-12-03/pdf/E7-23413.pdf Controlled Substances Definitions Drug Traffic Control 3 p. 67850 67852 72 FR 67850 Title 21 Part 1300 21 CFR Part 1300 RIN 1117-AA94 Definition of “Positional Isomer” as It Pertains to the Control of Schedule I Controlled Substances; Federal Register Vol. 72, Issue RULE E7-23413 DEPARTMENT OF JUSTICE Drug Enforcement Administration 2008-01-02 Docket No. DEA-260F 4410-09-P E7-23413 Final Rule.

On May 25, 2006, DEA published a Notice of Proposed Rulemaking which proposed the addition of a specific definition for the term "positional isomer" to allow for the systematic determination of which isomers of schedule I substances would be considered to be "positional," and therefore, subject to schedule I control. This rulemaking finalizes that definition. The Controlled Substances Act (CSA) and its implementing regulations specify which hallucinogenic substances are considered schedule I controlled substances. The CSA states that all salts, isomers, and salts of isomers of these substances are also schedule I controlled substances. In non-technical terms, an isomer of a substance is a different compound, but a compound which has the same number and kind of atoms. The terms "optical isomer" and "geometric isomer" are specific scientific terms and it is easy to determine whether one substance is an optical or geometric isomer of another. The term "positional isomer," however, is subject to scientific interpretation. The addition of a definition for the term "positional isomer" will assist legitimate research[ers] and industry in determining the control status of materials that are "positional isomers" of schedule I hallucinogens. While the DEA will remain the authority for ultimately determining the control status of a given material, providing a specific definition for "positional isomer" will ensure consistent criteria are utilized in making these determinations. This rule does not change existing laws, regulations, policies, processes, and procedures regarding the determination of control status for schedule I hallucinogenic substances. This rule merely makes available to the public the longstanding definition of "positional isomer" which DEA has used when making these scheduling determinations. This rule is relevant only to specialized forensic or research chemists. Most of these individuals are existing DEA registrants who are authorized by the DEA to handle schedule I hallucinogenic substances.

Effective January 2, 2008. Christine A. Sannerud, Ph.D., Chief, Drug and Chemical Evaluation Section, Office of Diversion Control, Drug Enforcement Administration, Washington, DC 20537 at (202) 307-7183. Controlled Substances Definitions Drug Traffic Control Schedules of controlled substances: Schedule I controlled substances; positional isomer definition, Vol. 72, no. 231 Office of the Federal Register, National Archives and Records Administration 2007-12-03 continuing daily deposited born digital 222 p. Table of Contents: AE 2.7: GS 4.107: AE 2.106: KF70.A2 https://www.govinfo.gov/app/details/FR-2007-12-03 P0b002ee18093f08d 0097-6326 0042-1219 0364-1406 769-004-00000-9 000582072 f:fr03de07 https://www.govinfo.gov/app/details/FR-2007-12-03 https://www.govinfo.gov/content/pkg/FR-2007-12-03/pdf/FR-2007-12-03.pdf https://www.govinfo.gov/content/pkg/FR-2007-12-03/xml/FR-2007-12-03.xml fdlp 67831 68039 DGPO 2010-09-22 2024-06-05 FR-2007-12-03 machine generated eng FR FR-2007-12-03 72 231