    [Public Papers of the Presidents of the United States: WILLIAM J. CLINTON (2000, Book I)]
    [June 26, 2000]
    [Pages 1267-1269]
    [From the U.S. Government Publishing Office www.gpo.gov]

    Remarks on the Completion of the First Survey of the Human Genome
    June 26, 2000

        The President.  Good morning. I want to, first of all, acknowledge
    Prime Minister Blair, who will join us by
    satellite in just a moment from London. I want to welcome here the
    Ambassadors from the United Kingdom,
    Japan, Germany,
    France. And I'd also like to
    acknowledge the contributions not only that their scientists but also
    scientists from China made to the vast international consortium that is
    the human genome project.
        I thank Secretary Shalala, who could
    not be here today, and Secretary Richardson,
    who is here; Dr. Ruth Kirschstein, Dr.
    Ari Patrinos, scientists of the
    Department of Health and Human Services and the Department of Energy,
    who have played an important role in the human genome project.
        I want to say a special word of thanks to my science adviser, Dr.
    Neal Lane, and of course, to Dr. Francis
    Collins, the director of the international
    human genome project, and to the Celera president, Craig Venter. I thank Senator Harkin and
    Senator Sarbanes for being here, and the
    other distinguished guests.
        Nearly two centuries ago, in this room, on this floor, Thomas
    Jefferson and a trusted aide spread out a magnificent map, a map
    Jefferson had long prayed he would get to see in his lifetime. The aide
    was Meriwether Lewis, and the map was the product of his courageous
    expedition across the American frontier, all the way to the Pacific. It
    was a map that defined the contours and forever expanded the frontiers
    of our continent and our imagination.
        Today the world is joining us here in the East Room to behold a map
    of even greater significance. We are here to celebrate the completion of
    the first survey of the entire human genome. Without a doubt, this is
    the most important, most wondrous map ever produced by humankind.
        The moment we are here to witness was brought about through
    brilliant and painstaking work of scientists all over the world,
    including many men and women here today. It was not even 50 years ago
    that a young Englishman named Crick and a
    brash, even younger American named Watson
    first discovered the elegant structure of our genetic code. Dr. Watson,
    the way you announced your discovery in the journal ``Nature'' was one
    of the great understatements of all time: ``This structure has novel
    features, which are of considerable biological interest.'' [Laughter]
    Thank you, sir.
        How far we have come since that day. In the intervening years, we
    have pooled the combined wisdom of biology, chemistry, physics,
    engineering, mathematics, and computer science; tapped the great
    strengths and insights of the public and private sectors. More than
    1,000 researchers across 6 nations have revealed nearly all 3 billion
    letters of our miraculous genetic code. I congratulate all of you on
    this stunning and humbling achievement.
        Today's announcement represents more than just an epic-making
    triumph of science and reason. After all, when Galileo discovered he
    could use the tools of mathematics and mechanics to understand the
    motion of celestial bodies, he felt, in the words of one eminent
    researcher, ``that he had learned the language in which God created the
    universe.''
        Today, we are learning the language in which God created life. We
    are gaining ever more awe for the complexity, the beauty, the wonder of
    God's most divine and sacred gift. With this profound new knowledge,
    humankind is on the verge of gaining immense new power to heal. Genome
    science will have a real impact on all our lives and even more on the
    lives of our

    [[Page 1268]]

    children. It will revolutionize the diagnosis, prevention, and treatment
    of most, if not all, human diseases.
        In coming years, doctors increasingly will be able to cure diseases
    like Alzheimer's, Parkinson's, diabetes, and cancer by attacking their
    genetic roots. Just to offer one example, patients with some forms of
    leukemia and breast cancer already are being treated in clinical trials
    with sophisticated new drugs that precisely target the faulty genes and
    cancer cells, with little or no risk to healthy cells. In fact, it is
    now conceivable that our children's children will know the term
    ``cancer'' only as a constellation of stars.
        But today's historic achievement is only a starting point. There is
    much hard work yet to be done. That is why I'm so pleased to announce
    that from this moment forward, the robust and healthy competition that
    has led us to this day and that always is essential to the progress of
    science will be coupled with enhanced public/private cooperation.
        Public and private research teams are committed to publishing their
    genomic data simultaneously later this year for the benefit of
    researchers in every corner of the globe. And after publication, both
    sets of teams will join together for an historic sequence analysis
    conference. Together, they will examine what scientific insights have
    been gleaned from both efforts and how we can most judiciously proceed
    toward the next majestic horizons.
        What are those next horizons? Well, first, we will complete a
    virtually error-free final draft of the human genome before the 50th
    anniversary of the discovery of the double helix, less than 3 years from
    now. Second, through sustained and vigorous support for public and
    private research, we must sort through this trove of genomic data to
    identify every human gene. We must discover the function of these genes
    and their protein products, and then we must rapidly convert that
    knowledge into treatments that can lengthen and enrich lives.
        I want to emphasize that biotechnology companies are absolutely
    essential in this endeavor, for it is they who will bring to the market
    the life-enhancing applications of the information from the human
    genome. And for that reason, this administration is committed to helping
    them to make the kind of long-term investments that will change the face
    of medicine forever.
        The third horizon that lies before us is one that science cannot
    approach alone. It is the horizon that represents the ethical, moral,
    and spiritual dimension of the power we now possess. We must not shrink
    from exploring that far frontier of science. But as we consider how to
    use new discovery, we must also not retreat from our oldest and most
    cherished human values. We must ensure that new genome science and its
    benefits will be directed toward making life better for all citizens of
    the world, never just a privileged few.
        As we unlock the secrets of the human genome, we must work
    simultaneously to ensure that new discoveries never pry open the doors
    of privacy. And we must guarantee that genetic information cannot be
    used to stigmatize or discriminate against any individual or group.
        Increasing knowledge of the human genome must never change the basic
    belief on which our ethics, our Government, our society are founded. All
    of us are created equal, entitled to equal treatment under the law.
    After all, I believe one of the great truths to emerge from this
    triumphant expedition inside the human genome is that in genetic terms,
    all human beings, regardless of race, are more than 99.9 percent the
    same.
        What that means is that modern science has confirmed what we first
    learned from ancient faiths. The most important fact of life on this
    Earth is our common humanity. My greatest wish on this day for the ages
    is that this incandescent truth will always guide our actions as we
    continue to march forth in this, the greatest age of discovery ever
    known.
        Now, it is my great pleasure to turn to my friend Prime Minister
    Tony Blair, who is joined in the State Dining
    Room at 10 Downing Street by Dr. Fred Sanger and
    other world-renowned scientists. With the generous support of the
    Wellcome Trust, British scientists have played an invaluable role in
    reaching this milestone.
        On behalf of the American people, I would like to thank the Prime
    Minister, the scientists, and the British nation
    for the brilliant work you have brought to this international effort.
        And Mr. Prime Minister, I would like to
    salute not only your unwavering support for genome research but also
    your visionary commitment to sparking ever-greater innovation across the
    full spectrum of science and technology. And on a personal note, I can't
    help but think that the year of your son's birth
    will always

    [[Page 1269]]

    be remembered for the remarkable achievements we announce today. I think
    his life expectancy has just gone up by about 25 years. [Laughter]

    [At this point, Prime Minister Tony Blair of the
    United Kingdom made remarks by satellite.]

        The President.  Tony, if I could, I would
    like to pick up on your last remark. I think everybody genuinely is
    concerned about the issues you raised, the privacy issues, and the whole
    general set of ethical, social, and legal issues. And it strikes me that
    our scientists--the British and the American scientists, our French,
    German, Chinese counterparts who worked on this--were working toward a
    single, clearly defined goal in all those countries and in the other
    countries of the world that will have to live with both the benefits and
    the challenges of these discoveries.
        There are different legal systems, different social mores, but I
    think that it would be a very good thing if the U.S, the U.K., and
    anybody else that wants to work with us could have the same sort of
    joint endeavor we've had with the human genome to deal with the
    implications of this, to deal with the legal, the social, the ethical
    implications. We may have differences from country to country, but I
    think that if we work together, we'll give a higher sense of urgency to
    the project, and we'll get a better product.
        And so I'm offering you another partnership.
    It's easy for me to do, because you'll have to do it, and I'll be gone.
    [Laughter]

    [Prime Minister Blair responded.]

        The President.  Thank you. Thank you very much, Tony.
        Now, in a few moments, we'll hear from Celera president Dr. Craig
    Venter, who shares in the glory of this day,
    and deservedly so because of his truly visionary pursuit of innovative
    strategies to sequence the human genome as rapidly as possible. And I
    thank you, Craig, for what you have done to make this day possible.
        And now I'd like to invite Dr. Francis Collins to the lectern. I also want to congratulate him. From
    his development of some of the central methods for finding human disease
    genes to his successful application of those methods to the discovery of
    the cystic fibrosis gene in 1989 to his current leadership for the
    international human genome project, he has combined the talents of
    rigorous science and a profound sensitivity to ethical, legal, and
    social issues. He is a physician-scientist of great faith, compassion,
    energy, and integrity. And he has truly helped us more than anyone else
    to understand how the marvels of genome science will actually improve
    human health.
        So Dr. Collins, please come up to the
    lectern.

    [Dr. Francis Collins, Director, National
    Human Genome Research Institute, and Dr. J. Craig Venter, president and chief scientific officer, Celera Genomics
    Corp., made brief remarks.]

        The President.  Well, thank you both for those remarkable
    statements. I suppose, in closing, the most important thing I could do
    is to associate myself with Dr. Venter's
    last statement. When we get this all worked out and we're all living to
    be 150--[laughter]--young people will still fall in love; old people
    will still fight about things that should have been resolved 50 years
    ago--[laughter]--we will all, on occasion, do stupid things; and we will
    all see the unbelievable capacity of humanity to be noble. This is a
    great day.
        Thank you very much.

     Note: The President spoke at 10:19 a.m. in the East Room at the White
    House. In his remarks, he referred to Ambassadors to the U.S.
    Christopher Meyer of the United Kingdom, Shunji Yanai of Japan, Juergen
    Chrobog of Germany, and Francois Bujon de l'Estang of France; Aristides
    Patrinos, Associate Director, Office of Science, Department of Energy;
    James D. Watson, president, Cold Spring Harbor Laboratory; Francis H.
    Crick, researcher, Cambridge Laboratory of Molecular Biology; Frederick
    Sanger, 1958 and 1980 Nobel Prize-winner for chemistry; and Prime
    Minister Blair's son, Leo. The transcript released by the Office of the
    Press Secretary also included the remarks of the Prime Minister Blair,
    Dr. Collins, and Dr. Venter.