[Federal Register Volume 91, Number 88 (Thursday, May 7, 2026)]
[Notices]
[Pages 24879-24880]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2026-09012]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2026-N-4291]


Teva Pharmaceuticals USA, Inc., et al.; Withdrawal of Approval of 
15 Abbreviated New Drug Applications

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice.

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SUMMARY: The Food and Drug Administration (FDA or Agency) is 
withdrawing approval of 15 abbreviated new drug applications (ANDAs) 
from multiple applicants. The applicants notified the Agency in writing 
that the drug products were no longer marketed and requested that the 
approval of the applications be withdrawn.

DATES: Approval is withdrawn as of June 8, 2026.

FOR FURTHER INFORMATION CONTACT: Martha Nguyen, Center for Drug 
Evaluation and Research, Food and Drug Administration, 10903 New 
Hampshire Ave., Bldg. 75, Rm. 1676, Silver Spring, MD 20993-0002, 301-
796-3471, [email protected].

SUPPLEMENTARY INFORMATION: The applicants listed in Table 1 have 
informed FDA that these drug products are no longer marketed and have 
requested that FDA withdraw approval of the applications under the 
process in Sec.  314.150(c) (21 CFR 314.150(c)). The applicants have 
also, by their requests, waived their opportunity for a hearing. 
Withdrawal of approval of an application or abbreviated application 
under Sec.  314.150(c) is without prejudice to refiling.

             Table 1--ANDAs for Which Approval Is Withdrawn
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      Application No.                Drug                Applicant
------------------------------------------------------------------------
ANDA 076905...............  Finasteride tablet, 1  Teva Pharmaceuticals
                             milligram (mg).        USA, Inc., 400
                                                    Interpace Parkway,
                                                    Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 077028...............  Cilostazol tablet,     Actavis Elizabeth
                             100 mg.                LLC. (an indirect,
                                                    wholly owned
                                                    subsidiary of Teva
                                                    Pharmaceuticals USA,
                                                    Inc.), 400 Interpace
                                                    Parkway, Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 077671...............  Amlodipine besylate    Watson Laboratories,
                             tablet, Equivalent     Inc. (an indirect,
                             to (EQ) 2.5 mg base,   wholly owned
                             EQ 5 mg base, and EQ   subsidiary of Teva
                             10 mg base.            Pharmaceuticals USA,
                                                    Inc.), 400 Interpace
                                                    Parkway, Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 077679...............  Carboplatin            Pharmachemie B.V. (an
                             injectable, 50 mg/5    indirect, wholly
                             milliliter (mL) (10    owned subsidiary of
                             mg/mL), 150 mg/15 mL   Teva Pharmaceuticals
                             (10 mg/mL), and 450    USA, Inc.), 400
                             mg/45 mL (10 mg/mL).   Interpace Parkway,
                                                    Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 078166...............  Ciprofloxacin          Par Health USA LLC.,
                             extended-release       U.S. Agent for PH
                             tablet, 212.6 mg; EQ   Health Limited, 9
                             287.5 mg base and      Great Valley
                             425.2 mg; EQ 574.9     Parkway, Malvern, PA
                             mg base.               19355.
ANDA 078631...............  Carboplatin            Pliva Lachema AS (an
                             injectable, 50 mg/5    indirect, wholly
                             mL (10 mg/mL), 150     owned subsidiary of
                             mg/15 mL (10 mg/mL),   Teva Pharmaceuticals
                             450 mg/45 mL (10 mg/   USA, Inc.), 400
                             mL), and 600 mg/60     Interpace Parkway,
                             mL (10 mg/mL).         MCC Blue Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 078724...............  Ezetimibe tablet, 10   Teva Pharmaceuticals
                             mg.                    USA, Inc.
ANDA 078984...............  Anastrozole tablet, 1  Watson Laboratories,
                             mg.                    Inc.
ANDA 089895...............  Chlorzoxazone tablet,  Barr Laboratories
                             500 mg.                LLC. (an indirect,
                                                    wholly owned
                                                    subsidiary of Teva
                                                    Pharmaceuticals USA,
                                                    Inc.), 400 Interpace
                                                    Parkway, Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 090797...............  Pantoprazole sodium    Actavis Totowa LLC.
                             delayed-release        (an indirect, wholly
                             tablet, EQ 20 mg       owned subsidiary of
                             base and EQ 40 mg      Teva Pharmaceuticals
                             base.                  USA, Inc.), 400
                                                    Interpace Parkway,
                                                    Building A,
                                                    Parsippany, NJ
                                                    07054.
ANDA 091539...............  Irbesartan and         Watson Laboratories,
                             hydrochlorothiazide    Inc.
                             tablet, 12.5 mg; 150
                             mg and 12.5 mg; 300
                             mg.
ANDA 202235...............  Ibandronate sodium     Freyr INC., U.S.
                             injectable, EQ 3 mg    Agent for CHEMI
                             base/3 mL.             S.p.A., 150 College
                                                    Rd. West, Suite 102,
                                                    Princeton, NJ 08540.
ANDA 210285...............  Dimethyl fumarate      Upsher-Smith
                             delayed-release        Laboratories, LLC.,
                             capsule, 120 mg and    U.S. Agent for Sawai
                             240 mg.                USA, Inc., 6701
                                                    Evenstad Dr. N,
                                                    Suite 300, Maple
                                                    Grove, MN 55369.
ANDA 213158...............  Esomeprazole           The WhiteOak Group,
                             magnesium delayed-     LLC., U.S. Agent for
                             release pellets        Cisen Pharmaceutical
                             capsule, EQ 20 mg      Co., Ltd., 1629 K
                             base and EQ 40 mg      St. NW, Suite 300,
                             base.                  Washington, DC
                                                    20006.
ANDA 216407...............  Ketorolac              Parexel
                             tromethamine tablet,   International, U.S.
                             10 mg.                 Agent for Atnahs
                                                    Pharma US Limited,
                                                    541 Church at North
                                                    Hills St., Suite
                                                    1000, Raleigh, NC
                                                    27609.
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[[Page 24880]]

    Therefore, approval of the applications listed in Table 1, and all 
amendments and supplements thereto, is hereby withdrawn as of June 8, 
2026. Approval of each entire application is withdrawn, including any 
strengths and dosage forms inadvertently missing from Table 1. 
Introduction or delivery for introduction into interstate commerce of 
products listed in Table 1 without an approved new drug application or 
ANDA violates sections 505(a) and 301(d) of the Federal Food, Drug, and 
Cosmetic Act (21 U.S.C. 355(a) and 331(d)). Drug products that are 
listed in Table 1 that are in inventory on June 8, 2026 may continue to 
be dispensed until the inventories have been depleted or the drug 
products have reached their expiration dates or otherwise become 
violative, whichever occurs first.

Grace R. Graham,
Deputy Commissioner for Policy, Legislation, and International Affairs.
[FR Doc. 2026-09012 Filed 5-6-26; 8:45 am]
BILLING CODE 4164-01-P