[Federal Register Volume 91, Number 56 (Tuesday, March 24, 2026)]
[Notices]
[Page 14031]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2026-05734]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Request for Information (RFI): Inviting Comments and Suggestions 
on a Framework for the NIH-Wide Strategic Plan for Fiscal Years 2027-
2031

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: This Request for Information (RFI) is intended to gather broad 
public input to assist the National Institutes of Health (NIH) in 
developing the NIH-Wide Strategic Plan for Fiscal Years 2027-2031 
(FY27-FY31). NIH invites input from stakeholders throughout the 
scientific research, advocacy, and clinical practice communities, as 
well as the general public, regarding the proposed framework for the 
FY27-FY31 NIH-Wide Strategic Plan. Organizations are strongly 
encouraged to submit a single response that reflects the views of their 
organization and their membership as a whole.

DATES: Comments regarding this information collection are best assured 
of having their full effect if received by May 26, 2026.

ADDRESSES: All comments must be submitted electronically on the 
submission website, available at https://rfi.grants.nih.gov/?s=6998c3a23eb404a3e80e8212.

FOR FURTHER INFORMATION CONTACT: Please direct all inquiries to: Marina 
Volkov, [email protected], 301.496.4147.

SUPPLEMENTARY INFORMATION: The purpose of the NIH-Wide Strategic Plan 
is to communicate how NIH will advance its mission to support research 
in pursuit of fundamental knowledge about the nature and behavior of 
living systems, and the application of that knowledge to enhance 
health, lengthen life, and reduce illness and disability.
    The current NIH-Wide Strategic Plan (available at: https://www.nih.gov/about-nih/nih-wide-strategic-plan), covering FY21-FY25, was 
submitted to Congress in July 2021. As part of implementing the 21st 
Century Cures Act (Pub. L. 114-255), NIH will update its Strategic 
Plan, no more than once every six years. The agency is currently 
developing the NIH-Wide Strategic Plan for FY27-FY31 and anticipates 
releasing it early FY27.
    The NIH-Wide Strategic Plan highlights NIH's approach towards the 
achievement of its mission while ensuring good stewardship of taxpayer 
funds. It is not intended to outline the myriads of important research 
opportunities for specific diseases or conditions. Nor will it focus on 
the specific research missions of each component Institute, Center and 
Office. Those opportunities are found within strategic plans that are 
specific to an Institute, Center, or Office, or specific to a 
particular disease or disorder. A list of Institute, Center, or Office-
specific, topical, and other NIH-wide or interagency strategic plans is 
available at https://report.nih.gov/strategicplans/.
    The Framework for the NIH-Wide Strategic Plan for FY27-FY31, below, 
articulates NIH's priorities in three key areas: biomedical and 
behavioral science research; scientific research capacity; and 
scientific research operations. These Priorities apply across NIH.

NIH-Wide Strategic Plan Framework

Priority 1: Research Areas

 Goal 1: Advance Foundational Knowledge of Human Health and 
Disease
 Goal 2: Prevent Disease and Promote Health Across the Lifespan
 Goal 3: Advance and Optimize Interventions, Treatments, and 
Cures

Priority 2: Research Capacity

 Goal 1: Develop and Sustain an Interdisciplinary Research 
Workforce
 Goal 2: Build, Improve, and Sustain Research Resources and 
Infrastructure

Priority 3: Research Operations

 Goal 1: Enhance Scientific Stewardship and Decision-Making
 Goal 2: Foster Transparency and Accountability to Improve 
Public Trust in Science

    The NIH seeks comments on, but not limited to, NIH's Goals across 
the three Priorities articulated in the framework--including potential 
benefits, drawbacks, opportunities, or challenges, and other areas of 
focus for consideration.
    NIH encourages organizations (e.g., patient advocacy groups, 
professional organizations) to submit a single response reflective of 
the views of the organization or membership as a whole.
    Responses to this RFI are voluntary and may be submitted 
anonymously. Please do not include any personally identifiable 
information or any information that you do not wish to make public. 
Proprietary, classified, confidential, or sensitive information should 
not be included in your response. The Government will use the 
information submitted in response to this RFI at its discretion. The 
Government reserves the right to use any submitted information on 
public websites, in reports, in summaries of the state of the science, 
in any possible resultant solicitation(s), grant(s), or cooperative 
agreement(s), or in the development of future funding opportunity 
announcements. This RFI is for informational and planning purposes only 
and is not a solicitation for applications or an obligation on the part 
of the Government to provide support for any ideas identified in 
response to it. Please note that the Government will not pay for the 
preparation of any information submitted or for use of that 
information.
    We look forward to your input and hope that you will share this RFI 
opportunity with your colleagues.

    Dated: March 17, 2026.
Matthew J. Memoli,
Principal Deputy Director, National Institutes of Health.
[FR Doc. 2026-05734 Filed 3-23-26; 8:45 am]
BILLING CODE 4140-01-P