[Federal Register Volume 90, Number 221 (Wednesday, November 19, 2025)]
[Notices]
[Pages 52038-52041]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2025-20244]


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DEPARTMENT OF COMMERCE

Patent and Trademark Office


Agency Information Collection Activities; Submission to the 
Office of Management and Budget for Review and Approval; Comment 
Request; Deposit of Biological Materials

AGENCY: United States Patent and Trademark Office, Department of 
Commerce.

ACTION: Notice of information collection; request for comments.

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SUMMARY: The United States Patent and Trademark Office (hereafter 
``USPTO'' or ``Agency''), as required by the Paperwork Reduction Act of 
1995, invites comments on the extension and revision of an existing 
information collection: 0651-0022 (Deposit of Biological Materials). 
The purpose of this notice is to allow 60 days for public comments 
preceding submission of the information collection to the Office of 
Management and Budget (OMB).

DATES: To ensure consideration, you must submit comments regarding this

[[Page 52039]]

information collection on or before January 20, 2026.

ADDRESSES: Interested persons are invited to submit written comments by 
any of the following methods. Do not submit Confidential Business 
Information or otherwise sensitive or protected information.
     Email: [email protected]. Include ``0651-
0022 comment'' in the subject line of the message.
     Federal eRulemaking Portal: http://www.regulations.gov.
     Mail: Justin Isaac, Office of the Chief Administrative 
Officer, United States Patent and Trademark Office, P.O. Box 1450, 
Alexandria, VA 22313-1450.
     Telephone: Raul Tamayo, Senior Legal Advisor, 571-272-
7728.

FOR FURTHER INFORMATION CONTACT: Requests for additional information 
should be directed to Raul Tamayo, Senior Legal Advisor at: Office of 
Patent Legal Administration, United States Patent and Trademark Office, 
P.O. Box 1450, Alexandria, VA 22313-1450; 571-272-7728; or 
[email protected] with ``0651-0022 comment'' in the subject line. 
Additional information about this information collection is also 
available at http://www.reginfo.gov under ``Information Collection 
Review.''

SUPPLEMENTARY INFORMATION: 

I. Abstract

    This information collection covers information from patent 
applicants who seek to deposit biological material for patent purposes 
according to 37 CFR 1.801-1.809. The information collected from such 
patent applicants consists of information and documentation 
demonstrating the applicant's compliance with regulatory requirements, 
as well as information regarding the biological sample after it is 
deposited. This collection also covers applications from institutions 
that wish to be recognized by the USPTO as a suitable depository to 
receive deposits for patent application purposes. The information 
collection requirements for these actions are separate, as discussed 
below.

A. Deposits of Biological Material

    The deposit of biological material for patent purposes is 
authorized by 35 U.S.C. 2(b)(2). The term ``biological material'' is 
defined in Sec.  1.801 as including material that is capable of self-
replication, either directly or indirectly. When an invention involves 
a biological material, words and figures may not sufficiently describe 
how to make and use the invention in a reproducible manner as required 
by 35 U.S.C. 112. In such cases, the inventive biological material must 
be known and readily available to the public or be capable to be made 
or isolated without undue experimentation (see Sec.  1.802). In order 
to satisfy the ``known and readily available'' requirement, the 
biological material may be deposited in a suitable depository that has 
been recognized as an International Depository Authority (IDA) 
established under the Budapest Treaty per Sec.  1.803(a)(1), or any 
other depository recognized to be suitable by the USPTO per Sec.  
1.803(a)(2). Under the authority of 35 U.S.C. 2(b)(2), the deposit 
rules (Sec. Sec.  1.801-1.809) set forth the examination procedures and 
conditions of deposit which must be satisfied in the event a deposit is 
required.
    In cases where a deposit of biological material that is capable of 
self-replication either directly or indirectly is made, and the deposit 
is not made under the Budapest Treaty, the USPTO collects information 
to determine whether the deposit meets the viability requirements of 
Sec.  1.807. This information includes a viability statement under 
Sec.  1.807 identifying:
    (1) The name and address of the depository where the deposit was 
made;
    (2) The name and address of the depositor;
    (3) The date of the deposit;
    (4) The identity of the deposit and the accession number given by 
the depository;
    (5) The date of the viability test;
    (6) The procedure used to obtain a sample if the test was not done 
by the depository; and
    (7) A statement that the deposit is capable of reproduction.
    A viability statement is not required when a deposit is made and 
accepted under the Budapest Treaty.
    This information collection also covers additional information that 
may be gathered by the USPTO after a biological material is deposited 
into the recognized depository. For example, depositors may be required 
to submit verification statements for biological material deposited 
after the effective filing date of a patent application, or written 
notification that an acceptable deposit will be made. As another 
example, occasionally a deposit may become lost, contaminated, or 
incapable of functioning as described in the specification, and a 
replacement or supplemental deposit needs to be made. This information 
collection includes the written notification that the depositor must 
submit to the USPTO disclosing the particulars of the need for a 
replacement or supplemental deposit, as well as the request for 
certificate of correction that is required when the replacement or 
supplemental deposit is being made in connection with a patent.
    The USPTO does not provide forms for the information it collects in 
connection with the deposit of biological material. The International 
Bureau of the World Intellectual Property Organization provides forms 
for the deposit of biological material at an IDA under the Budapest 
Treaty.

B. Depositories

    Institutions that wish to be recognized by the USPTO as a suitable 
depository to receive deposits for patent purposes are required by 
Sec.  1.803(b) to make a request demonstrating that they are qualified 
to store and test the biological material submitted to them under 
patent applications (see also MPEP 2405). This information collection 
covers the information that a depository must submit when seeking 
recognition by the USPTO as a suitable depository under Sec.  
1.803(a)(2). Depositories should comply with the requirements of Sec.  
1.803(b) when requesting to become a recognized depository.
    This information enables the USPTO to evaluate whether such a 
depository has internal practices (both technical and administrative) 
and the technical ability sufficient to protect the integrity of the 
biological material being stored by U.S. patent applicants. The 
information that the depository provides includes:
    (1) The name and address of the depository seeking recognition 
under Sec.  1.803(a)(2),
    (2) Detailed information as to the capacity of the depository to 
comply with the requirements of Sec.  1.803(a)(2), including 
information on its legal status, scientific standing, staff, and 
facilities;
    (3) An indication that the depository intends to be available, for 
the purposes of deposit, to any depositor under these same conditions;
    (4) Where the depository intends to accept for deposit only certain 
kinds of biological material, such kinds must be specified; and
    (5) An indication of the amount of any fees that the depository 
will, upon acquiring the status of a suitable depository under 
paragraph (a)(2) of this section, charge for storage, viability 
statements and furnishings of the samples of the deposit.
    This collection also includes additional information gathered by 
the USPTO that may be needed after a depository has been recognized by 
the USPTO under Sec.  1.803(a)(2). This information could include 
requests to handle additional types of biological

[[Page 52040]]

material other than the material originally recognized, viability 
statements that depositories may submit on behalf of depositors for 
deposits tested at the depository, and documentation that the public 
has been notified about where to obtain samples.

II. Method of Collection

    Items in this information collection may be submitted 
electronically. Applicants may also submit the information in paper 
form by mail, fax, or hand delivery.

III. Data

    OMB Control Number: 0651-0022.
    Forms: (BP = Budapest)

 BP/1 (Statement in the Case of an Original Deposit (Rule 6.1))
 BP/2 (Statement in the Case of a New Deposit with the Same 
International Depository Authority (Rule 6.2))
 BP/3 (Statement in the Case of a New Deposit with Another 
International Depository Authority (Rule 6.2))
 BP/9 (Viability Statement (Rule 10.2) (International Form))

    Type of Review: Extension and revision of a currently approved 
information collection.
    Affected Public: Private sector.
    Respondent's Obligation: Required to obtain or retain benefits.
    Frequency: On occasion.
    Estimated Number of Annual Respondents: 1,501 respondents.
    Estimated Number of Annual Responses: 1,501 responses.
    Estimated Time per Response: The USPTO estimates that the responses 
in this information collection will take the public approximately 1 to 
5 hours to complete, depending on the complexity of the situation. This 
includes the time to gather the necessary information, create the 
document, and submit the completed item to the USPTO.
    Estimated Total Annual Respondent Burden Hours: 1,505 hours.
    Estimated Total Annual Respondent Hourly Cost Burden: $672,735.

                                  Table 1--Total Reporting Burden Hours and Hourly Costs to Private Sector Respondents
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                                                                                                                                             Estimated
                                         Estimated     Responses per    Estimated annual  Estimated time     Estimated     Rate \1\ ($/       annual
    Item No.             Item             annual         respondent        responses       for response    burden (hour/       hour)        respondent
                                        respondents                                           (hours)          year)                        Cost Burden
                                                 (a)              (b)    (a) x (b) = (c)             (d)     (c) x (d) =             (f)     (e) x (f) =
                                                                                                                     (e)                             (g)
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1...............  Deposited                    1,500                1              1,500               1           1,500             447        $670,500
                   Materials.
2...............  Request for                      1                1                  1               5               5             447          $2,235
                   Depository
                   Approval.
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    Totals......  ..................           1,501  ...............              1,501  ..............           1,505  ..............        $672,735
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\1\ 2023 Report of the Economic Survey, published by the Committee on Economics of Legal Practice of the American Intellectual Property Law Association,
  pg. F-41. The USPTO uses the average billing rate for intellectual property work in all firms, which is $447 per hour (www.aipla.org/home/news-publications/economic-survey).

    Estimated Total Annual Respondent Non-hourly Cost Burden: 
$4,306,511. There are no maintenance costs, recordkeeping costs, or 
filing fees associated with this information collection. However, the 
USPTO estimates that the total annual non-hour cost burden for this 
information collection, in the form of capital start-up costs and 
postage, is $4,306,511.
Capital Start-Up Costs
    Depositories charge fees to depositors, and all depositories charge 
about the same rates for their services. For example, the American Type 
Culture Collection (ATCC), one of the world's leading biological supply 
houses and recognized patent depositories, offers comprehensive patent 
services for $2,500 per deposit.\2\ Any deposit made from outside the 
U.S. may have additional requirements from other federal agencies as 
part of their importation process. For the purposes of this information 
collection, the USPTO estimates that the depository fee is $2,500 per 
deposit. The breakout for these costs is listed in the table below.
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    \2\ The ATCC Patent Depository service fee is $2,500 per 
deposit, which is incurred at the time of receipt of a portion or 
all of the materials (https://www.atcc.org/services/depositing-with-atcc/patent-deposit).

                                         Table 2--Capital Start Up Costs
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                                                          Estimated annual                      Non-hourly cost
             Item No.                       Item              responses      Filing fee ($)         burden
                                                                       (a)               (b)     (a) x (b) = (c)
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1.................................  Deposited Material               1,500             2,500          $3,750,000
                                     Depository Fee.
                                                         -------------------------------------------------------
    Totals........................  ....................             1,500  ................          $3,750,000
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Postage Costs
    Biological deposits are generally shipped to the depository 
``Domestic Overnight'' by Federal Express (FedEx). Since depositors are 
urged to supply frozen or freeze-dried materials, it must be packed in 
dry ice. Dry ice itself is considered a dangerous good and requires 
special packaging. Additional FedEx special handling charges for 
inaccessible dangerous goods shipments is $73 per shipment,\3\ which 
applies to temperature-sensitive biological materials and dry ice.
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    \3\ FedEx, How to Ship Dangerous Goods (https://www.fedex.com/en-us/service-guide/dangerous-goods/how-to-ship.html).
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    An average cost for shipping by FedEx ``Domestic Overnight'' can 
vary depending on the size of the package, the delivery time, and the 
delivery distance. For purposes of this information collection, the 
USPTO estimates that the FedEx Domestic Overnight charge for a 
biological deposit is $120 per shipment. If the shipment requires a 
pick-up by FedEx, there is an

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additional charge of $7.50.\4\ Special packaging is also required for 
these shipments. The average cost of frozen infectious shipments is 
estimated to be $170 per package of four for specimen shipments 
requiring refrigeration or dry ice. Therefore, the USPTO estimates that 
the total average postage cost is $371 per shipment. The USPTO 
estimates that respondents to this information collection will ship 
1,500 biological deposits, for a total of $556,500. The USPTO estimate 
that it will receive 1 depository request for recognition. The USPTO 
estimates that the postage cost for this type of mailed submission, 
using a Priority Mail legal flat-rate envelope, will be $11.20. 
Combining these rates, the USPTO therefore estimates that the total 
mailing costs for this information collection is $556,511 per year.
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    \4\ FedEx, U.S. Parcel Pickup Options (https://www.fedex.com/content/dam/fedex-com/hdn/FedEx-US-Pickup-Options-with-rates-2025.pdf).
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IV. Request for Comments

    The USPTO is soliciting public comments to:
    (a) Evaluate whether the collection of information is necessary for 
the proper performance of the functions of the Agency, including 
whether the information will have practical utility;
    (b) Evaluate the accuracy of the Agency's estimate of the burden of 
the collection of information, including the validity of the 
methodology and assumptions used;
    (c) Enhance the quality, utility, and clarity of the information to 
be collected; and
    (d) Minimize the burden of the collection of information for those 
who are to respond, including through the use of appropriate automated, 
electronic, mechanical, or other technological collection techniques or 
other forms of information technology, e.g., permitting electronic 
submission of responses.
    All comments submitted in response to this notice are a matter of 
public record. The USPTO will include or summarize each comment in the 
request to OMB to approve this information collection. Before including 
an address, phone number, email address, or other personally 
identifiable information (PII) in a comment, be advised that the entire 
comment--including PII--may be made publicly available at any time. 
While you may request to withhold PII from public view, the USPTO 
cannot guarantee that it will be able to do so.

Justin Isaac,
Information Collections Officer, Office of the Chief Administrative 
Officer, United States Patent and Trademark Office.
[FR Doc. 2025-20244 Filed 11-18-25; 8:45 am]
BILLING CODE 3510-16-P