[Federal Register Volume 90, Number 217 (Thursday, November 13, 2025)]
[Notices]
[Page 50944]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2025-19878]


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ENVIRONMENTAL PROTECTION AGENCY

[EPA-HQ-OPPT-2018-0443; FRL-12964-02-OCSPP]


Octamethylcyclotetrasiloxane (Cyclotetrasiloxane, 
2,2,4,4,6,6,8,8-octamethyl-)(D4); Draft Risk Evaluation Under the Toxic 
Substances Control Act (TSCA); Extension of the Comment Period

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice; extension of comment period.

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SUMMARY: In the Federal Register of September 17, 2025, Environmental 
Protection Agency (EPA) announced the availability of and sought public 
comment on a draft risk evaluation under the Toxic Substances Control 
Act (TSCA) for Octamethylcyclotetrasiloxane (Cyclotetrasiloxane, 
2,2,4,4,6,6,8,8-octamethyl-) (D4) (CASRN 556-67-2). The purpose of risk 
evaluations under TSCA is to determine whether a chemical substance 
presents an unreasonable risk of injury to health or the environment 
under the conditions of use (COUs), including unreasonable risk to 
potentially exposed or susceptible subpopulations identified as 
relevant to the risk evaluation by EPA, and without consideration of 
costs or non-risk factors. EPA used the best available science to 
prepare this draft risk evaluation and to preliminarily determine, 
based on the weight of scientific evidence, that D4 poses unreasonable 
risk to health and the environment driven primarily by COUs analyzed in 
the draft risk evaluation. This document extends the comment period, 
which was scheduled to end on November 17, 2025, for 15 days.

DATES: The comment period for the document published on September 17, 
2025, at 90 FR 44821 (FRL-12964-01-OCSPP) is extended. Comments must be 
received on or before December 2, 2025; 15 days after November 17, 
2025.

ADDRESSES: Submit your comments, identified by docket identification 
(ID) number EPA-HQ-OPPT-2018-0443, online at https://www.regulations.gov. Follow the online instructions for submitting 
comments. Do not submit electronically any information you consider to 
be Confidential Business Information (CBI) or other information whose 
disclosure is restricted by statute. Additional instructions on 
commenting and visiting the docket, along with more information about 
dockets generally, is available at https://www.epa.gov/dockets.

FOR FURTHER INFORMATION CONTACT: 
    For technical information: Scott Drewes, Existing Chemical Risk 
Management Division (7404M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, 
DC 20460-0001; telephone number: (202) 564-8833; email address: 
[email protected].
    For general information on TSCA: The TSCA Assistance Information 
Service Hotline, Goodwill Vision Enterprises, 422 South Clinton Ave., 
Rochester, NY 14620; telephone number: (800) 471-7127 or (202) 554-
1404; email address: [email protected].

SUPPLEMENTARY INFORMATION: To give stakeholders additional time to 
review materials and prepare comments, EPA is hereby extending the 
comment period established in the Federal Register document of 
September 17, 2025, at 90 FR 44821 (FRL-12964-01-OCSPP) for 15 days, 
from November 17, 2025, to December 2, 2025. More information on the 
action can be found in the Federal Register of September 17, 2025.
    EPA provided a concurrent public comment period soliciting public 
comment on the draft documents and charge questions to be provided to 
the Octamethylcyclotetrasiloxane (D4); Draft Risk Evaluation; Science 
Advisory Committee on Chemicals (SACC) Peer Review; Notice of SACC 
Meeting; Availability of Draft Documents and Request for Comment (90 FR 
45204, September 19, 2025) (FRL-12975-01-OCSPP), docket identification 
number EPA-HQ-OPPT-2025-1610. EPA is not reopening the peer review 
public comment period with this notice or delaying the SACC peer review 
meeting for D4. The opportunity to provide information to EPA via the 
Octamethylcyclotetrasiloxane (D4); TSCA Review docket (EPA-HQ-OPPT-
2018-0443) on requested information will now continue through December 
2, 2025.
    To submit comments or access the docket, please follow the detailed 
instructions provided under ADDRESSES. If you have questions, consult 
the technical person listed under FOR FURTHER INFORMATION CONTACT.
    Authority: 15 U.S.C. 2601 et seq.

    Dated: November 10, 2025.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.
[FR Doc. 2025-19878 Filed 11-12-25; 8:45 am]
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