[Federal Register Volume 90, Number 186 (Monday, September 29, 2025)]
[Notices]
[Pages 46609-46610]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2025-18806]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2025-N-0352]


Agency Information Collection Activities; Submission for Office 
of Management and Budget Review; Comment Request; Guidance for Industry 
on Establishing That a Tobacco Product Was Commercially Marketed in the 
United States

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice.

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SUMMARY: The Food and Drug Administration (FDA) is announcing that a 
proposed collection of information has been submitted to the Office of 
Management and Budget (OMB) for review and clearance under the 
Paperwork Reduction Act of 1995.

DATES: Submit written comments (including recommendations) on the 
collection of information by October 29, 2025.

ADDRESSES: To ensure that comments on the information collection are 
received, OMB recommends that written comments be submitted to https://www.reginfo.gov/public/do/PRAMain. Find this particular information 
collection by selecting ``Currently under Review--Open for Public 
Comments'' or by using the search function. The OMB control number for 
this information collection is 0910-0775. Also include the FDA docket 
number found in brackets in the heading of this document.

FOR FURTHER INFORMATION CONTACT: Amber Sanford, Office of Operations, 
Food and Drug Administration, Three White Flint North, 10 a.m.-12 p.m, 
11601 Landsdown St., North Bethesda, MD 20852, 301-796-8867, 
[email protected].

SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, FDA has 
submitted the following proposed collection of information to OMB for 
review and clearance.

Guidance for Industry on Establishing That a Tobacco Product Was 
Commercially Marketed in the United States as of February 15, 2007

OMB Control Number 0910-0775--Extension

    This information collection supports Food and Drug Administration 
guidance. The Federal Food, Drug, and Cosmetic Act (FD&C Act) 
authorizes FDA to regulate the manufacture, marketing, and distribution 
of tobacco products to protect the public health generally and to 
reduce tobacco use by minors.
    Tobacco products are governed by chapter IX of the FD&C Act 
(sections 900 through 920) (21 U.S.C. 387 through 387t). Section 
201(rr) of the FD&C Act (21 U.S.C. 321(rr)), as amended, defines a 
tobacco product as any product made or derived from tobacco, or 
containing nicotine from any source, that is intended for human 
consumption, including any component, part, or accessory of a tobacco 
product (except for raw materials other than tobacco used in 
manufacturing a component, part, or accessory of a tobacco product). 
Section 910 of the FD&C Act sets out premarket requirements for new 
tobacco products. The term new tobacco product is defined as any 
tobacco product (including those products in test markets) that was not 
commercially marketed in the United States as of February 15, 2007, or 
any modification (including a change in design, any component, any 
part, or any constituent, including a smoke constituent, or in the 
content, delivery, or form of nicotine, or any other additive or 
ingredient) of a tobacco product where the modified product was 
commercially marketed in the United States after February 15, 2007 
(section 910(a)(1) of the FD&C Act).
    FDA refers to tobacco products that were commercially marketed 
(including those products in test markets) in the United States as of 
February 15, 2007, as Pre-Existing tobacco products. Pre-Existing 
tobacco products are not considered new tobacco products and are not 
subject to the premarket requirements of section 910 of the FD&C Act. 
The guidance document associated with this information collection 
provides information on how a manufacturer may establish that a tobacco 
product was commercially marketed in the United States as of February 
15, 2007. A Pre-Existing tobacco product (except such products 
exclusively in test markets) may also serve as the predicate tobacco 
product in a section 905(j) report (intended to be used toward 
demonstrating substantial equivalence) for a new tobacco product 
(section 905(j)(1)A)(i)) of the FD&C Act.
    The guidance document ``Establishing That a Tobacco Product Was 
Commercially Marketed in the United States as of February 15, 2007 
(Revised)'' (2023) (https://www.fda.gov/regulatory-information/search-fda-guidance-documents/establishing-tobacco-product-was-commercially-marketed-united-states-february-15-2007-revised) recommends that the 
manufacturer submit information adequate to demonstrate that the 
tobacco product was commercially marketed in the United States as of 
February 15, 2007. Examples of such information may include, but are 
not limited to, the following: dated copies of advertisements, dated 
catalog pages, dated promotional material, and dated bills of lading.
    In the Federal Register of June 27, 2025 (90 FR 27632), FDA 
published a 60-day notice requesting public comment on the proposed 
collection of information. No comments were received.
    FDA estimates the burden of this collection of information as 
follows:

[[Page 46610]]



                                                     Table 1--Estimated Annual Reporting Burden \1\
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                                                                                         Number of                       Average burden
                              Activity                                  Number of      responses per     Total annual     per response     Total hours
                                                                       respondents       respondent       responses        (in hours)
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Submit evidence of commercial marketing in the United States as of              500                1              500                5            2,500
 February 15, 2007.................................................
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\1\ There are no capital costs or operating and maintenance costs associated with this collection of information.

    FDA's estimate of the number of respondents is based on the fact 
that requesting an Agency determination of the Pre-Existing status of a 
tobacco product under the guidance is not required and also on the 
number of Pre-Existing tobacco product submissions received from 2011 
to October 2024. All new tobacco products require a marketing 
authorization order from FDA before introducing such products in the 
U.S. market. If a deemed new tobacco product was on the market as of 
August 8, 2016, a marketing application was required to be submitted by 
September 9, 2020 as required by the Court, and as set forth in the 
Center for Tobacco Products compliance policy (see exception for 
premium cigars).\1\ A marketing application must be submitted and 
receive authorization to market a new tobacco product that was not on 
the market as of August 8, 2016.\2\ The number of hours to gather the 
evidence is FDA's estimate of how long it might take a manufacturer to 
review, gather, and submit dated information if making a request for 
Agency determination.
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    \1\ Cigar Ass'n of Am. v. FDA, No. 16-cv-01460, Dkt. No. 277 
(D.D.C. Aug. 9, 2023). FDA has appealed this decision. See https://www.fda.gov/regulatory-information/search-fda-guidance-documents/enforcement-priorities-electronic-nicotine-delivery-system-ends-and-other-deemed-products-market.
    \2\ See https://www.fda.gov/tobacco-products/manufacturing/
submit-tobacco-product-applications-deemed-tobacco-
products#:~:text=On%20August%208%2C%202016%2C%20all,authorization%20r
equirements%20in%20the%20Federal.
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    FDA further estimates it would take a manufacturer approximately 5 
hours to put together this collection of evidence and to submit the 
package to FDA for review. FDA estimates that it would take 
approximately 2,500 hours annually to respond to this collection of 
information.
    We have adjusted our burden estimate, which has resulted in a 
decrease to the currently approved burden. Our estimated burden for the 
information collection reflects an overall decrease of 2,500 hours and 
a corresponding decrease of 500 responses. The number of submissions 
FDA received to establish marketing as of February 15, 2007 has 
decreased and we have therefore revised the number of respondents to 
the information collection based on this data.

Grace R. Graham,
Deputy Commissioner for Policy, Legislation, and International Affairs.
[FR Doc. 2025-18806 Filed 9-26-25; 8:45 am]
BILLING CODE 4164-01-P