[Federal Register Volume 90, Number 107 (Thursday, June 5, 2025)]
[Notices]
[Pages 23931-23932]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2025-10200]


=======================================================================
-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[EPA-HQ-OPPT-2018-0503 and EPA-HQ-OPPT-2018-0433; FRL-12808-01-OCSPP]


Dibutyl Phthalate (DBP) and Diethylhexyl Phthalate (DEHP); Draft 
Risk Evaluations Under the Toxic Substances Control Act (TSCA); Notice 
of Availability and Request for Comment

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The Environmental Protection Agency (EPA or Agency) is 
announcing the availability of and seeking public comment on the draft 
risk evaluations under the Toxic Substances Control Act (TSCA) for 
Dibutyl Phthalate (DBP) (CASRN 84-74-2) and Diethylhexyl Phthalate 
(DEHP) (CARSN 117-81-7). The purpose of risk evaluations under TSCA is 
to determine whether a chemical substance presents an unreasonable risk 
of injury to health or the environment under the conditions of use, 
including unreasonable risk to potentially exposed or susceptible 
subpopulations identified as relevant to the risk evaluation by EPA, 
and without consideration of costs or non-risk factors. EPA used the 
best available science to prepare this draft risk evaluation and to 
preliminarily determine, based on the weight of scientific evidence, 
that DBP and DEHP present unreasonable risk to health and the 
environment driven primarily by certain conditions of use analyzed in 
the draft evaluations.

DATES: Comments must be received on or before August 4, 2025.

ADDRESSES: Submit your comments, identified by docket identification 
(ID) number EPA-HQ-OPPT-2018-0503, online at https://www.regulations.gov. Follow the online instructions for submitting 
comments. Do not submit electronically any information you consider to 
be Confidential Business Information (CBI) or other information whose 
disclosure is restricted by statute. Additional instructions on 
commenting and visiting the docket, along with more information about 
dockets generally, is available at https://www.epa.gov/dockets.

FOR FURTHER INFORMATION CONTACT: 
    For technical information on DBP: Carolyn Mottley, Existing 
Chemical Risk Management Division (7404M), Office of Pollution 
Prevention and Toxics, Environmental Protection Agency, 1200 
Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: 
(202) 566-1955; email address: [email protected].
    For technical information on DEHP: Dyllan Taylor, Existing Chemical 
Risk Management Division (7404M), Office of Pollution Prevention and 
Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, 
Washington, DC 20460-0001; telephone number: (202) 564-2913; email 
address: [email protected].
    For general information: The TSCA-Hotline, ABVI-Goodwill, 422 South 
Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; 
email address: [email protected].

SUPPLEMENTARY INFORMATION:

I. Executive Summary

A. Does this action apply to me?

    This action is directed to the public in general and may be of 
particular interest to those involved in the manufacture (defined under 
TSCA section 3(9) to include import), processing, distribution, use, 
and disposal of DBP and DEHP, related industry trade organizations, 
non-governmental organizations with an interest in human and 
environmental health, state and local governments, Tribal Nations, and/
or those interested in the assessment of risks involving chemical 
substances and mixtures regulated under TSCA. As such, the Agency has 
not attempted to describe all the specific entities that this action 
might apply to. If you need help determining applicability, consult the 
appropriate technical contact listed under FOR FURTHER INFORMATION 
CONTACT.

B. What is the Agency's authority for taking this action?

    The Agency is conducting this risk evaluation under TSCA section 6, 
15 U.S.C. 2605, which requires that EPA conduct risk evaluations on 
chemical substances and identifies the minimum components EPA must 
include in the risk evaluations. Each risk evaluation must be conducted 
consistent with the best available science, be based on the weight of 
the scientific evidence, and consider reasonably available information, 
and not consider costs or non-risk factors. 15 U.S.C. 2625(h), (i), and 
(k). See also the implementing procedural regulations at 40 CFR part 
702.

C. What action is the Agency taking?

    EPA is announcing the availability of and seeking public comment on 
these draft risk evaluations conducted under TSCA for DBP and DEHP. The 
purpose of risk evaluation under TSCA is to determine whether a 
chemical substance presents an unreasonable risk of injury to health or 
the environment under the conditions of use, including unreasonable 
risk to potentially exposed or susceptible subpopulations identified as 
relevant to the risk evaluation by EPA, and without consideration of 
costs or non-risk factors. EPA has used the best available science to 
prepare this draft risk evaluation and, based on the weight of 
scientific evidence, to preliminarily determine that DBP and DEHP 
present unreasonable risk to health and the environment driven 
primarily by certain conditions of use analyzed in the draft 
evaluations.

D. What should I consider as I prepare my comments?

    1. Submitting CBI. Do not submit CBI to EPA through https://www.regulations.gov or email. If you wish to include CBI in your 
comment, please follow the applicable instructions at https://www.epa.gov/dockets/commenting-epa-dockets#rules and clearly mark the 
information that you claim to be CBI. Information so marked will not be 
disclosed except in accordance with procedures set forth in 40 CFR 
parts 2 and 703, as applicable.
    2. Tips for preparing your comments. When preparing and submitting 
your comments, see the commenting tips at https://www.epa.gov/dockets/commenting-epa-dockets.

II. Background

A. What are DBP and DEHP?

    DBP is a common chemical name for the chemical substance 1,2-
Benzenedicarboxylic acid, 1,2-dibutylester (CASRN 84-74-2). DEHP is a 
common chemical name for the chemical substance 1,2-Benzenedicarboxylic 
acid, 1,2-bis(2-ethylhexyl) ester (CASRN 117-81-7). DBP and DEHP are 
manufactured (including imported), processed, distributed, and disposed 
as part of industrial, commercial, and consumer conditions of use. DBP 
and DEHP are used primarily as plasticizers in polyvinyl chloride 
(PVC). These phthalates are also used in adhesives, sealants, paints, 
coatings, rubbers, and

[[Page 23932]]

non-PVC plastics, as well as for other applications. Between 2016 and 
2019 the productions volumes of DBP and DEHP were between 1 to 10 
million pounds and between 10 to 50 million pounds, respectively, based 
on the 2020 TSCA Chemical Data Reporting data.

B. Summary of Activities for the Risk Evaluations of DBP and DEHP

    In December 2019, EPA announced its designation of DBP and DEHP as 
high priority substances for risk evaluation under TSCA (Ref. 1). In 
June 2020, EPA sought public comment on the draft scopes of the DBP and 
DEHP risk evaluations (Ref. 2), and, after considering public comments, 
issued the final scope in September 2020 (Ref. 3). These documents, 
other supporting documents, and public comments are in the docket 
established for each chemical at https://www.regulations.gov. In 
addition, as will be announced separately in the Federal Register, the 
draft risk evaluations for DBP and DEHP will also undergo peer review 
by the Science Advisory Committee on Chemicals (SACC) and will be 
included in the SACC peer review docket (Docket ID No. EPA-HQ-OPPT-
2024-0551), along with other materials related to that peer review.

III. Request for Comment

    EPA seeks feedback on the assessment of risk presented in the draft 
risk evaluations for DBP (Docket ID No. EPA-HQ-OPPT-2018-0503) and DEHP 
(Docket ID No. EPA-HQ-OPPT-2018-0433), which are available in the 
chemical specific dockets as identified, and encourages all potentially 
interested parties, including individuals, governmental and non-
governmental organizations, non-profit organizations, academic 
institutions, research institutions, and private sector entities to 
comment on the draft risk evaluations. To the extent possible, the 
Agency asks commenters to please cite any public data related to or 
that support comments provided, and to the extent permissible, describe 
any supporting data that are not publicly available.
    EPA welcomes specific input on each section of the draft risk 
evaluation for each chemical, and is particularly interested in 
comments and information related to the following topics:
     Information on the use of personal protective equipment 
(PPE) and engineering controls during the manufacture, processing, and 
use of DBP and DEHP for each condition of use.
     Information that could be used to replace upper-bound or 
screening level assumptions, particularly for the conditions of use 
that may significantly contribute to unreasonable risk;
     Application of the Revised Draft Technical Support 
Document for the Cumulative Risk Analysis (CRA) within the individual 
chemical risk evaluations;
     The use of transcriptomics data in the weight of 
scientific evidence for environmental hazard assessment of DBP and the 
environmental hazard assessment of DEHP;
     The human health and environmental hazard endpoints used 
in the risk characterizations;
     Application of a flux-limited approach to estimating 
dermal absorption; and
     Approaches used to estimate chemical migration rate for 
ingestion via mouthing in the consumer exposure assessments.

IV. Next Steps

    After consideration of comments received from the public and the 
SACC on the draft risk evaluations, EPA will issue final risk 
evaluations for DBP and DEHP. A separate forthcoming Federal Register 
notice will announce the peer review by the SACC.
    Under TSCA section 6, EPA must determine in the final risk 
evaluations, based on the weight of scientific evidence, whether or not 
the chemicals present an unreasonable risk to health or the environment 
under the chemical's conditions of use. This includes consideration of 
risks to potentially exposed susceptible subpopulations (PESS) who may 
be at greater risks than the general population, such as children and 
workers. TSCA prohibits EPA from considering non-risk factors (e.g., 
costs/benefits) during risk evaluation.
    If EPA determines that a chemical presents an unreasonable risk to 
health or the environment, the chemical will move to risk management 
action under TSCA section 6(a) for the relevant conditions of use. EPA 
is required to implement, via regulation, regulatory restrictions on 
the manufacture (including import), processing, distribution, use or 
disposal of the chemical to eliminate the identified unreasonable risk. 
EPA is given a range of risk management options under TSCA, including 
labeling, recordkeeping or notice requirements, actions to reduce human 
exposure or environmental release, and a ban of the chemical or of 
certain uses. Like the prioritization and risk evaluation processes, 
there is an opportunity for public comment on any proposed risk 
management actions.
    For more information about the TSCA risk evaluation process for 
existing chemicals, go to https://www.epa.gov/assessing-and-managing-chemicals-under-tsca.

V. References

    The following is a listing of the documents that are specifically 
referenced in this document. The docket includes these documents and 
other information considered by EPA, including documents that are 
referenced within the documents that are included in the docket, even 
if the referenced document is not physically located in the docket. For 
assistance in locating these other documents, please consult the person 
listed under FOR FURTHER INFORMATION CONTACT.

1. EPA. High-Priority Substance Designations Under the Toxic 
Substances Control Act (TSCA) and Initiation of Risk Evaluation on 
High-Priority Substances; Notice of Availability. Federal Register. 
84 FR 71924, December 30, 2019 (FRL-10003-15).
2. EPA. Draft Scopes of the Risk Evaluations To Be Conducted for 
Seven Chemical Substances Under the Toxic Substances Control Act; 
Notice of Availability. Federal Register. 85 FR 22733, April 23, 
2020 (FRL-10008-05).
3. EPA. Final Scopes of the Risk Evaluations To Be Conducted for 
Twenty Chemical Substances Under the Toxic Substances Control Act; 
Notice of Availability. Federal Register. 85 FR 55281, September 4, 
2020 (FRL-10013-90).

    Authority: 15 U.S.C. 2601 et seq.

    Dated: May 30, 2025.
Nancy B. Beck,
Principal Deputy Assistant Administrator, Office of Chemical Safety and 
Pollution Prevention.
[FR Doc. 2025-10200 Filed 6-4-25; 8:45 am]
BILLING CODE 6560-50-P