[Federal Register Volume 89, Number 120 (Friday, June 21, 2024)]
[Rules and Regulations]
[Pages 51978-51981]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2024-13588]


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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 180

[EPA-HQ-OPP-2023-0608; FRL-12022-01-OCSPP]


Poly(oxy-1,2-ethanediyl), Polymer With 1,2-ethandiol, 2-methyl-
1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-
benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-
ethyl-2-(hydroxymethyl)-1,3-propanediol in Pesticide Formulations; 
Tolerance Exemption

AGENCY: Environmental Protection Agency (EPA).

ACTION: Final rule.

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SUMMARY: This regulation establishes an exemption from the requirement 
of a tolerance for residues of poly(oxy-1,2-ethanediyl), polymer with 
1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-
benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol, with a minimum number average molecular weight (in amu) of 
1400, (No CAS Reg. No.), when used as an inert ingredient in a 
pesticide chemical formulation. Pyxis Regulatory Consulting Inc., on 
behalf of Tessara PTY Ltd., submitted a petition to EPA under the 
Federal Food, Drug, and Cosmetic Act (FFDCA), requesting an exemption 
from the requirement of a tolerance. This regulation eliminates the 
need to establish a maximum permissible level for residues of poly(oxy-
1,2-ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, 
hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic 
acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-ethyl-2-
(hydroxymethyl)-1,3-propanediol on food or feed commodities when used 
in accordance with these exemptions.

DATES: This regulation is effective June 21, 2024. Objections and 
requests for hearings must be received on or before August 20, 2024 and 
must be filed in accordance with the instructions provided in 40 CFR 
part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).

ADDRESSES: The docket for this action, identified by docket 
identification (ID) number EPA-HQ-OPP-2023-0608, is available at 
https://www.regulations.gov or at the Office of Pesticide Programs 
Regulatory Public Docket (OPP Docket) in the Environmental Protection 
Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., 
Rm. 3334, 1301 Constitution Ave. NW, Washington, DC 20460-0001. The 
Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room and the OPP Docket is (202) 566-1744. Please review the 
visitor instructions and additional information about the docket 
available at https://www.epa.gov/dockets.

FOR FURTHER INFORMATION CONTACT: Charles Smith, Director, Registration 
Division (7505T), Office of Pesticide Programs, Environmental 
Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-
0001; main telephone number: (202) 566-1030; email address: 
[email protected].

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this action apply to me?

    You may be potentially affected by this action if you are an 
agricultural producer, food manufacturer, or pesticide manufacturer. 
The following list of North American Industrial Classification System 
(NAICS) codes is not intended to be exhaustive, but rather provides a 
guide to help readers determine whether this document applies to them. 
Potentially affected entities may include:
     Crop production (NAICS code 111).
     Animal production (NAICS code 112).
     Food manufacturing (NAICS code 311).
     Pesticide manufacturing (NAICS code 32532).

B. How can I get electronic access to other related information?

    You may access a frequently updated electronic version of 40 CFR 
part 180 through the Office of the Federal Register's e-CFR site at 
https://www.ecfr.gov/current/title-40.

C. Can I file an objection or hearing request?

    Under FFDCA section 408(g), 21 U.S.C. 346a(g), any person may file 
an objection to any aspect of this regulation and may also request a 
hearing on those objections. You must file your objection or request a 
hearing on this regulation in accordance with the instructions provided 
in 40 CFR part 178. To ensure proper receipt by EPA, you must identify 
docket ID number: EPA-HQ-OPP-2023-0608 in the subject line on the first 
page of your submission. All objections and requests for a hearing must 
be in writing and must be received by the Hearing Clerk on or before 
August 20, 2024. Addresses for mail and hand delivery of objections and 
hearing requests are provided in 40 CFR 178.25(b), although the Office 
of the Administrative Law Judges, which houses the Hearing Clerk, 
encourages parties to file objections and hearing requests 
electronically. See https://www.epa.gov/sites/default/files/2020-05/documents/2020-04-10_-_order_urging_electronic_service_and_filing.pdf.
    In addition to filing an objection or hearing request with the 
Hearing Clerk as described in 40 CFR part 178, please submit a copy of 
the filing (excluding any Confidential Business Information (CBI)) for 
inclusion in the public docket. Information not marked confidential 
pursuant to 40 CFR part 2 may be disclosed publicly by EPA without 
prior notice. Submit the non-CBI copy of your objection or hearing 
request, identified by docket ID number EPA-HQ-OPP-2023-0608, by one of 
the following methods.
     Federal eRulemaking Portal: https://www.regulations.gov. 
Follow the online instructions for submitting comments. Do not submit 
electronically any information you consider to be CBI or other 
information whose disclosure is restricted by statute.
     Mail: OPP Docket, Environmental Protection Agency Docket 
Center (EPA/DC), (28221T), 1200 Pennsylvania Ave. NW, Washington, DC 
20460-0001.
     Hand Delivery: To make special arrangements for hand 
delivery or delivery of boxed information, please follow the 
instructions at https://www.epa.gov/dockets/where-send-comments-epa-dockets#express.
    Additional instructions on commenting or visiting the docket, along 
with more information about dockets generally, is available at https://www.epa.gov/dockets.

II. Background and Statutory Findings

    In the Federal Register of March 22, 2024 (89 FR 20410) (FRL-11682-
02-OCSPP), EPA issued a document pursuant to FFDCA section 408, 21 
U.S.C. 346a, announcing the receipt of a pesticide petition (PP IN-
11735) filed

[[Page 51979]]

by poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-
propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-
benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-
ethyl-2-(hydroxymethyl)-1,3-propanediol with a minimum number average 
molecular weight (in amu) of 1400, (No CAS Reg. No.), Pyxis Regulatory 
Consulting Inc., 4110 136th St., Ct., NW, Gig Harbor, WA 98332, on 
behalf of Tessara PTY Ltd., 35 Kimball Avenue Epping 2 Cape Town 7460 
S. Africa. The petition requested that 40 CFR 180.960 be amended by 
establishing an exemption from the requirement of a tolerance for 
residues of poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 2-
methyl-1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 
1,3-benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] 
and 2-ethyl-2-(hydroxymethyl)-1,3-propanediol with a minimum number 
average molecular weight (in amu) of 1400, (No CAS Reg. No.). That 
document included a summary of the petition prepared by the petitioner 
and solicited comments on the petitioner's request. The Agency did not 
receive any comments.
    Section 408(c)(2)(A)(i) of FFDCA allows EPA to establish an 
exemption from the requirement for a tolerance (the legal limit for a 
pesticide chemical residue in or on a food) only if EPA determines that 
the exemption is ``safe.'' Section 408(c)(2)(A)(ii) of FFDCA defines 
``safe'' to mean that ``there is a reasonable certainty that no harm 
will result from aggregate exposure to the pesticide chemical residue, 
including all anticipated dietary exposures and all other exposures for 
which there is reliable information.'' This includes exposure through 
drinking water and use in residential settings but does not include 
occupational exposure. Section 408(b)(2)(C) of FFDCA requires EPA to 
give special consideration to exposure of infants and children to the 
pesticide chemical residue in establishing an exemption from the 
requirement of a tolerance and to ``ensure that there is a reasonable 
certainty that no harm will result to infants and children from 
aggregate exposure to the pesticide chemical residue . . .'' and 
specifies factors EPA is to consider in establishing an exemption.

III. Risk Assessment and Statutory Findings

    EPA establishes exemptions from the requirement of a tolerance only 
in those cases where it can be shown that the risks from aggregate 
exposure to pesticide chemical residues under reasonably foreseeable 
circumstances will pose no appreciable risks to human health. In order 
to determine the risks from aggregate exposure to pesticide inert 
ingredients, the Agency considers the toxicity of the inert in 
conjunction with possible exposure to residues of the inert ingredient 
through food, drinking water, and through other exposures that occur as 
a result of pesticide use in residential settings. If EPA is able to 
determine that a finite tolerance is not necessary to ensure that there 
is a reasonable certainty that no harm will result from aggregate 
exposure to the inert ingredient, an exemption from the requirement of 
a tolerance may be established.
    Consistent with FFDCA section 408(b)(2)(D), EPA has reviewed the 
available scientific data and other relevant information in support of 
this action and considered its validity, completeness and reliability 
and the relationship of this information to human risk. EPA has also 
considered available information concerning the variability of the 
sensitivities of major identifiable subgroups of consumers, including 
infants and children. In the case of certain chemical substances that 
are defined as polymers, the Agency has established a set of criteria 
to identify categories of polymers expected to present minimal or no 
risk. The definition of a polymer is given in 40 CFR 723.250(b) and the 
exclusion criteria for identifying these low-risk polymers are 
described in 40 CFR 723.250(d). Poly(oxy-1,2-ethanediyl), polymer with 
1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-
benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol, conforms to the definition of a polymer given in 40 CFR 
723.250(b) and meets the following criteria that are used to identify 
low-risk polymers.
    1. The polymer is not a cationic polymer nor is it reasonably 
anticipated to become a cationic polymer in a natural aquatic 
environment.
    2. The polymer does contain as an integral part of its composition 
at least two of the atomic elements carbon, hydrogen, nitrogen, oxygen, 
silicon, and sulfur.
    3. The polymer does not contain as an integral part of its 
composition, except as impurities, any element other than those listed 
in 40 CFR 723.250(d)(2)(ii).
    4. The polymer is neither designed nor can it be reasonably 
anticipated to substantially degrade, decompose, or depolymerize. An 
available biodegradation study supports that poly(oxy-1,2-ethanediyl), 
polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 
1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol with a minimum number average molecular weight (in amu) of 
1400, (No CAS Reg. No.), is not readily biodegradable (MRID: 52034702).
    5. The polymer is manufactured or imported from monomers and/or 
reactants that are already included on the TSCA Chemical Substance 
Inventory or manufactured under an applicable TSCA section 5 exemption.
    6. The polymer is not a water absorbing polymer with a number 
average molecular weight (MW) greater than or equal to 10,000 Daltons.
    7. The polymer does not contain certain perfluoroalkyl moieties 
consisting of a CF3- or longer chain length as listed in 40 CFR 
723.250(d)(6). Additionally, the polymer also meets as required the 
following exemption criteria: specified in 40 CFR 723.250(e): The 
polymer's number average MW of 1400 Daltons is greater than 1,000, and 
less than 10,000 Daltons. However, the polymer contains less than 10% 
oligomeric material below MW 500, and less than 25% oligomeric material 
below MW 1,000, and the polymer has a combined (total) reactive group 
equivalent weight greater than or equal to 1,000 for the reactive 
functional groups listed in 40 CFR 723.250(e)(1)(ii)(B).
    Thus, poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 2-
methyl-1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 
1,3-benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] 
and 2-ethyl-2-(hydroxymethyl)-1,3-propanediol, meets the criteria for a 
polymer to be considered low risk under 40 CFR 723.250. Based on its 
conformance to the criteria in this unit, no mammalian toxicity is 
anticipated from dietary, inhalation, or dermal exposure to poly(oxy-
1,2-ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, 
hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic 
acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-ethyl-2-
(hydroxymethyl)-1,3-propanediol.

IV. Aggregate Exposures

    For the purposes of assessing potential exposure under this 
exemption, EPA considered that poly(oxy-1,2-ethanediyl), polymer with 
1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-

[[Page 51980]]

benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol could be present in all raw and processed agricultural 
commodities and drinking water, and that non-occupational non-dietary 
exposure was possible. The number average MW of poly(oxy-1,2-
ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, 
hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic 
acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-ethyl-2-
(hydroxymethyl)-1,3-propanediol is 1400 Daltons. Generally, a polymer 
of this size would be poorly absorbed through the intact 
gastrointestinal tract or through intact human skin. Since poly(oxy-
1,2-ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, 
hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic 
acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-ethyl-2-
(hydroxymethyl)-1,3-propanediol conforms to the criteria that identify 
a low-risk polymer, there are no concerns for risks associated with any 
potential exposure scenarios that are reasonably foreseeable. The 
Agency has determined that a tolerance is not necessary to protect the 
public health.

V. Cumulative Effects From Substances With a Common Mechanism of 
Toxicity

    Section 408(b)(2)(D)(v) of FFDCA requires that, when considering 
whether to establish, modify, or revoke a tolerance, the Agency 
consider ``available information'' concerning the cumulative effects of 
a particular pesticide's residues and ``other substances that have a 
common mechanism of toxicity.''
    EPA has not found poly(oxy-1,2-ethanediyl), polymer with 1,2-
ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-
benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol to share a common mechanism of toxicity with any other 
substances, and poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 
2-methyl-1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic 
acid, 1,3-benzenedicarboxylic acid, 1,1'-methylenebis[4-
isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-propanediol does 
not appear to produce a toxic metabolite produced by other substances. 
For the purposes of this tolerance exemption, therefore, EPA has 
assumed that poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 2-
methyl-1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 
1,3-benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] 
and 2-ethyl-2-(hydroxymethyl)-1,3-propanediol does not have a common 
mechanism of toxicity with other substances. For information regarding 
EPA's efforts to determine which chemicals have a common mechanism of 
toxicity and to evaluate the cumulative effects of such chemicals, see 
EPA's website at https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/cumulative-assessment-risk-pesticides.

VI. Additional Safety Factor for the Protection of Infants and Children

    Section 408(b)(2)(C) of FFDCA provides that EPA shall apply an 
additional tenfold (10X) margin of safety for infants and children in 
the case of threshold effects to account for prenatal and postnatal 
toxicity and the completeness of the database on toxicity and exposure 
unless EPA determines based on reliable data that a different margin of 
safety will be safe for infants and children. Due to the expected low 
toxicity of poly(oxy-1,2-ethanediyl), polymer with 1,2-ethandiol, 2-
methyl-1,3-propanediol, hexanedioic acid, 1,4-benzenedicarboxylic acid, 
1,3-benzenedicarboxylic acid, 1,1'-methylenebis[4-isocyanatobenzene] 
and 2-ethyl-2-(hydroxymethyl)-1,3-propanediol, EPA has not used a 
safety factor analysis to assess the risk. For the same reasons no 
additional safety factor is needed for assessing risk to infants and 
children.

VII. Determination of Safety

    Based on the conformance to the criteria used to identify a low-
risk polymer, EPA concludes that there is a reasonable certainty of no 
harm to the U.S. population, including infants and children, from 
aggregate exposure to residues of poly(oxy-1,2-ethanediyl), polymer 
with 1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-
benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol.

VIII. Other Considerations

Analytical Enforcement Methodology

    An analytical method is not required for enforcement purposes since 
the Agency is establishing an exemption from the requirement of a 
tolerance without any numerical limitation.

IX. Conclusion

    Accordingly, EPA finds that exempting residues of poly(oxy-1,2-
ethanediyl), polymer with 1,2-ethandiol, 2-methyl-1,3-propanediol, 
hexanedioic acid, 1,4-benzenedicarboxylic acid, 1,3-benzenedicarboxylic 
acid, 1,1'-methylenebis[4-isocyanatobenzene] and 2-ethyl-2-
(hydroxymethyl)-1,3-propanediol from the requirement of a tolerance 
will be safe.

X. Statutory and Executive Order Reviews

    This action establishes a tolerance exemption under FFDCA section 
408(d) in response to a petition submitted to the Agency. The Office of 
Management and Budget (OMB) has exempted these types of actions from 
review under Executive Order 12866, entitled ``Regulatory Planning and 
Review'' (58 FR 51735, October 4, 1993). Because this action has been 
exempted from review under Executive Order 12866, this action is not 
subject to Executive Order 13211, entitled ``Actions Concerning 
Regulations That Significantly Affect Energy Supply, Distribution, or 
Use'' (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled 
``Protection of Children from Environmental Health Risks and Safety 
Risks'' (62 FR 19885, April 23, 1997). This action does not contain any 
information collections subject to OMB approval under the Paperwork 
Reduction Act (PRA) (44 U.S.C. 3501 et seq.), nor does it require any 
special considerations under Executive Order 12898, entitled ``Federal 
Actions to Address Environmental Justice in Minority Populations and 
Low-Income Populations'' (59 FR 7629, February 16, 1994).
    Since tolerances and exemptions that are established on the basis 
of a petition under FFDCA section 408(d), such as the tolerance 
exemption in this final rule, do not require the issuance of a proposed 
rule, the requirements of the Regulatory Flexibility Act (RFA) (5 
U.S.C. 601 et seq.), do not apply.
    This action directly regulates growers, food processors, food 
handlers, and food retailers, not States or Tribes, nor does this 
action alter the relationships or distribution of power and 
responsibilities established by Congress in the preemption provisions 
of FFDCA section 408(n)(4). As such, the Agency has determined that 
this action will not have a substantial direct effect on States or 
Tribal governments, on the relationship between the National Government 
and the States or Tribal governments, or on the distribution of power 
and responsibilities among the various levels of government or between 
the Federal Government and Indian tribes. Thus, the Agency has 
determined that Executive Order 13132, entitled

[[Page 51981]]

``Federalism'' (64 FR 43255, August 10, 1999), and Executive Order 
13175, entitled ``Consultation and Coordination with Indian Tribal 
Governments'' (65 FR 67249, November 9, 2000), do not apply to this 
action. In addition, this action does not impose any enforceable duty 
or contain any unfunded mandate as described under Title II of the 
Unfunded Mandates Reform Act (UMRA) (2 U.S.C. 1501 et seq.).
    This action does not involve any technical standards that would 
require Agency consideration of voluntary consensus standards pursuant 
to section 12(d) of the National Technology Transfer and Advancement 
Act (NTTAA) (15 U.S.C. 272 note).

XI. Congressional Review Act

    Pursuant to the Congressional Review Act (5 U.S.C. 801 et seq.), 
EPA will submit a report containing this rule and other required 
information to the U.S. Senate, the U.S. House of Representatives, and 
the Comptroller General of the United States prior to publication of 
the rule in the Federal Register. This action is not a ``major rule'' 
as defined by 5 U.S.C. 804(2).

List of Subjects in 40 CFR Part 180

    Environmental protection, Administrative practice and procedure, 
Agricultural commodities, Pesticides and pests, Reporting and 
recordkeeping requirements.

    Dated: June 12, 2024.
Charles Smith,
Director, Registration Division, Office of Pesticide Programs.

    Therefore, for the reasons stated in the preamble, EPA is amending 
40 CFR chapter I as follows:

PART 180--TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES 
IN FOOD

0
1. The authority citation for part 180 continues to read as follows:

    Authority: 21 U.S.C. 321(q), 346a and 371.


0
2. In Sec.  180.960, amend table 1 to Sec.  180.960 by adding, in 
alphabetical order, the polymer ``Poly(oxy-1,2-ethanediyl), polymer 
with 1,2-ethandiol, 2-methyl-1,3-propanediol, hexanedioic acid, 1,4-
benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, 1,1'-
methylenebis[4-isocyanatobenzene] and 2-ethyl-2-(hydroxymethyl)-1,3-
propanediol, with a minimum number average molecular weight (in amu) of 
1400'' to read as follows:


Sec.  180.960  Polymers; exemptions from the requirement of a 
tolerance.

* * * * *

                        Table 1 to Sec.   180.960
------------------------------------------------------------------------
                 Polymer                              CAS No.
------------------------------------------------------------------------
 
                              * * * * * * *
Poly(oxy-1,2-ethanediyl), polymer with                            None.
 1,2-ethandiol, 2-methyl-1,3-propanediol,
 hexanedioic acid, 1,4-
 benzenedicarboxylic acid, 1,3-
 benzenedicarboxylic acid, 1,1'-
 methylenebis[4-isocyanatobenzene] and 2-
 ethyl-2-(hydroxymethyl)-1,3-propanediol,
 with a minimum number average molecular
 weight (in amu) of 1400.................
 
                              * * * * * * *
------------------------------------------------------------------------


[FR Doc. 2024-13588 Filed 6-20-24; 8:45 am]
BILLING CODE 6560-50-P