[Federal Register Volume 89, Number 40 (Wednesday, February 28, 2024)]
[Notices]
[Page 14670]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2024-04060]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: The invention listed below is owned by an agency of the U.S. 
Government and is available for licensing to achieve expeditious 
commercialization of results of federally-funded research and 
development. Foreign patent applications are filed on selected 
inventions to extend market coverage for companies and may also be 
available for licensing.

FOR FURTHER INFORMATION CONTACT: Wade Green at (301) 761-7505 or 
[email protected]. Licensing information may be obtained by communicating 
with the Technology Transfer and Intellectual Property Office, National 
Institute of Allergy and Infectious Diseases, 5601 Fishers Lane, 
Rockville, MD 20852: tel. 301-496-2644. A signed Confidential 
Disclosure Agreement will be required to receive copies of unpublished 
information related to the invention.

SUPPLEMENTARY INFORMATION: Technology description follows:
    An Innovative Adapter for Expedited and Automated Thawing of viably 
Frozen Cells.

Description of Technology

    This technology is a device and system for expediting the thawing 
frozen specimens (e.g., cryopreserved cells) contained in cryo-vials, 
offering a breakthrough solution for researchers seeking efficiency and 
precision in their workflows. The device is equipped with a small 
elongated tubular adaptor that suspends a cryo-vial of frozen cells 
over a centrifuge tube containing culture medium in an inverted 
position. With a focus on speed, efficiency and automation, the adaptor 
dramatically expedites the process of recovering viable cells from 
frozen specimens. It reduces per-sample labor time for thawing from 
several minutes to a few seconds, enabling a single technician to 
simultaneously thaw multiple vials within the capacity of centrifuges. 
The cells, once thawed, are diluted instantly into growth medium 
contained in the centrifuge tubes and spend essentially no time in 
liquid cryopreservative.
    The automated mechanism ensures a precise and controlled thawing 
environment maintaining optimal temperature conditions throughout the 
thawing process.
    Potential Commercial Applications:
     This device can be used in sample preparation and cell 
culturing.
     Applicable for research materials, medical and non-medical 
devices and consumer products.
    Competitive Advantages:
     Provides a faster process of recovering viable cells from 
frozen specimens.
     Eliminates multi-step processes.
     High throughput system with reduced variability.
     Constant environment control.
    Development Stage:
     Prototype
    Inventors: Dr. Mario Roederer, Dr. Pratip Chattopadhyay and 
Margaret Beddall, all of NIAID.
    Publications: n/a.
    Intellectual Property: HHS Reference No. E-080-2015-0-EIR-00 U.S. 
Patent Application No. 14/661,449, filed on March 18, 2015; Published 
Patent Application US20160274004A1 on September 22, 2016; U.S. Patent 
9,663,812 issued May 30, 2017.
    Licensing Contact: To license this technology, please contact Wade 
Green at (301) 761-7505 or [email protected]. and reference E-080-2015.
    Collaborative Research Opportunity: The National Institute of 
Allergy and Infectious Diseases is seeking statements of capability or 
interest from parties interested in collaborative research to further 
develop, evaluate, or commercialize this technology. For collaboration 
opportunities, please contact Wade Green at (301) 761-7505 or 
[email protected].

    Dated: February 7, 2024.
Surekha Vathyam,
Deputy Director, Technology Transfer and Intellectual Property Office, 
National Institute of Allergy and Infectious Diseases.
[FR Doc. 2024-04060 Filed 2-27-24; 8:45 am]
BILLING CODE 4140-01-P