[Federal Register Volume 86, Number 244 (Thursday, December 23, 2021)]
[Notices]
[Page 72988]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2021-27910]



[[Page 72988]]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Announcement of Availability of the Fifteenth Report on 
Carcinogens

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: The Department of Health and Human Services released the 15th 
Report on Carcinogens (RoC) to the public on December 21, 2021. The 
report is available on the RoC website at: https://ntp.niehs.nih.gov/go/roc or from the Office of the RoC (see ADDRESSES below).

DATES: The 15th RoC is available to the public on December 21, 2021.

ADDRESSES: Dr. Ruth Lunn, Integrated Health Effects Branch, Division of 
the NTP, NIEHS, P.O. Box 12233, MD K2-14, Research Triangle Park, NC 
27709; telephone: (919) 316-4637; FAX: (301) 480-2970; 
[email protected].

FOR FURTHER INFORMATION CONTACT: Questions or comments concerning the 
15th RoC should be directed to Dr. Ruth Lunn (telephone: 919-316-4637 
or [email protected]).

SUPPLEMENTARY INFORMATION:

Background Information on the RoC

    This notice is in accordance with the Public Health Service Act 
Section 301(b)(4). The Report on Carcinogens (RoC) is a Congressionally 
mandated document that identifies and discusses agents, substances, 
mixtures, or exposure circumstances (collectively referred to as 
``substances'') that may pose a hazard to human health because of their 
carcinogenicity. Substances are listed in the report as either known or 
reasonably anticipated to be human carcinogens. The listing of a 
substance in the RoC indicates a potential hazard; it does not 
establish the exposure conditions that pose a cancer hazard to 
individuals in their daily lives. For each listed substance, the RoC 
provides information from cancer studies that support the listing, as 
well as information about potential sources of exposure and current 
federal regulations to limit exposures. Each edition of the RoC is 
cumulative, that is, it lists newly reviewed substances in addition to 
substances listed in the previous edition. Information about the RoC is 
available on the RoC website (http://ntp.niehs.nih.gov/go/roc) or by 
contacting Dr. Lunn (see ADDRESSES above).
    The National Institute of Environmental Health Science, National 
Toxicology Program (NTP) prepares the RoC on behalf of the Secretary of 
Health and Human Services. For the 15th RoC, NTP followed an 
established, multi-step process with multiple opportunities for public 
input, and used established criteria to evaluate the scientific 
evidence on each candidate substance under review (http://ntp.niehs.nih.gov/go/rocprocess).

New Listings in the 15th RoC

    The 15th RoC contains 256 listings, some of which consist of a 
class of structurally related chemicals or agents. There are eight new 
listings in this edition. The new listing in the category of known to 
be a human carcinogen is Helicobacter pylori (chronic infection). Seven 
of the new listings are in the category of reasonably anticipated to be 
a human carcinogen: Antimony trioxide and six haloacetic acids found as 
water disinfection by-products, including bromochloroacetic acid, 
bromodichloroacetic acid, chlorodibromoacetic acid, dibromoacetic acid, 
dichloroacetic acid, and tribromoacetic acid.

    Dated: December 20, 2021.
Richard P. Woychik,
Director, National Institute of Environmental Health Science and 
National Toxicology Program.
[FR Doc. 2021-27910 Filed 12-22-21; 8:45 am]
BILLING CODE 4140-01-P