[Federal Register Volume 85, Number 174 (Tuesday, September 8, 2020)]
[Notices]
[Pages 55493-55497]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2020-19805]


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DEPARTMENT OF JUSTICE

Drug Enforcement Administration

[Docket No. DEA-708]


Bulk Manufacturer of Controlled Substances Application: Cayman 
Chemical Company

AGENCY: Drug Enforcement Administration, Justice.

[[Page 55494]]


ACTION: Notice of application.

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SUMMARY: Cayman Chemical Company has applied to be registered as a bulk 
manufacturer of basic class(es) controlled substances. Refer to 
Supplemental Information listed below for further drug information.

DATES: Registered bulk manufacturers of the affected basic class(es), 
and applicants therefore, may file written comments on or objections to 
the issuance of the proposed registration on or before November 9, 
2020. Such persons may also file a written request for a hearing on the 
application on or before November 9, 2020.

ADDRESSES: Written comments should be sent to: Drug Enforcement 
Administration, Attention: DEA Federal Register Representative/DPW, 
8701 Morrissette Drive, Springfield, Virginia 22152. All requests for a 
hearing must be sent to: Drug Enforcement Administration, Attn: 
Administrator, 8701 Morrissette Drive, Springfield, Virginia 22152. All 
requests for a hearing should also be sent to: (1) Drug Enforcement 
Administration, Attn: Hearing Clerk/OALJ, 8701 Morrissette Drive, 
Springfield, Virginia 22152; and (2) Drug Enforcement Administration, 
Attn: DEA Federal Register Representative/DPW, 8701 Morrissette Drive, 
Springfield, Virginia 22152.

SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 1301.33(a), this 
is notice that on July 17, 2020, Cayman Chemical Company, 1180 East 
Ellsworth Road, Ann Arbor, Michigan 48108-2419, applied to be 
registered as a bulk manufacturer of the following basic class(es) of 
controlled substances:

------------------------------------------------------------------------
                                                       Drug
                Controlled substance                   code    Schedule
------------------------------------------------------------------------
3-Fluoro-N-methylcathinone (3-FMC); 1-(3-               1233          I
 Fluorophenyl)-2-(Methylamino)Propan-1-one)........
Cathinone..........................................     1235          I
Methcathinone......................................     1237          I
4-Fluoro-N-methylcathinone (4-FMC); Flephedrone; 1-     1238          I
 ( 4-Fluorophenyl)-2-(Methylamino)Propan-1-one)....
Pentedrone ([alpha]-methylaminovalerophenone), its      1246          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
Mephedrone (4-Methyl-N-methylcathinone)............     1248          I
4-Methyl-N-ethylcathinone (4-MEC)..................     1249          I
Naphyrone, its optical, positional and geometric        1258          I
 isomers, salts and salts of isomers...............
N-Ethylamphetamine.................................     1475          I
N,N-Dimethylamphetamine............................     1480          I
Fenethylline.......................................     1503          I
Aminorex...........................................     1585          I
4-Methylaminorex (cis isomer)......................     1590          I
Gamma Hydroxybutyric Acid..........................     2010          I
Methaqualone.......................................     2565          I
Mecloqualone.......................................     2572          I
JWH-250 (1-Pentyl-3-(2-methoxyphenylacetyl) indole)     6250          I
SR-18 (Also known as RCS-8) (1-Cyclohexylethyl-3-(2-    7008          I
 methoxyphenylacetyl) indole)......................
ADB-FUBINACA (n-(1-amino-3,3-dimethyl-1-oxobutan-2-     7010          I
 yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide).
5-Flouro-UR-144 and XLR11 [1-(5-Fluoro-pentyl)1H-       7011          I
 indol-3-yl](2,2,3,3-
 tetramethylcyclopropyl)methanone..................
AB-FUBINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-    7012          I
 (4-fluorobenzyl)-1H-indazole-3-carboxamide).......
FUB-144............................................     7014          I
JWH-019 (1-Hexyl-3-(1-naphthoyl)indole)............     7019          I
MDMB-FUBINACA (Methyl 2-(1-4-fluorobenzyl)-1H-          7020          I
 indazole-3-carboxamido)-3,3-dimethylbutanoate)....
2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3-      7021          I
 methylbutanoate...................................
AB-PINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-      7023          I
 pentyl-1H-indazole-3-carboxamide).................
THJ-2201 [1-(5-fluoropentyl)-1H-indazol-3-              7024          I
 yl](naphthalen-1-yl)methanone.....................
5F-AB-PINACA.......................................     7025          I
AB-CHMINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-    7031          I
 (cyclohexylmethyl)-1H-indazole-3-carboxamide......
MAB-CHMINACA (N-(1-amino-3,3dimethyl-1-oxobutan-2-      7032          I
 yl)-1-(cyclohexylmethyl)-1H-indazole-3-
 carboxamide)......................................
5F-AMB (Methyl 2-(1-(5-fluoropentyl)-1H-indazola-3-     7033          I
 carboxamido)-3-methylbutanoate)...................
5F-ADB; 5F-MDMB-PINACA (Methyl 2-(1-(5fluoropentyl)-    7034          I
 1H-indazole-3-carboxamido)-3,3dimethylbutanoate)..
ADB-PINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-       7035          I
 yl)-1-pentyl-1H-indazole-3-carboxamide)...........
5F-EDMB-PINACA.....................................     7036          I
5F-MDMB-PICA)......................................     7041          I
MDMB-CHMICA, MMB-CHMINACA (Methyl 2-(1-                 7042          I
 (cyclohenxylmethyl)-1H-indole-3-carboxamido)-3,3-
 dimethylbutanote)-................................
MMB-CHMICA.........................................     7044          I
FUB-AKB48;FUB-APINACA; AKB48 N-(4-Fluorobenzyl)....     7047          I
APINACA and AKB48 N-(1-Adamantyl)-1-pentyl-1H-          7048          I
 indazole-3-carboxamide............................
5F-APINACA, 5F-AKB48 (N-(adamantan-1-yl)-1-             7049          I
 (5fluoropentyl)-1H-indazole-3-carboxamide)........
JWH-081 (1-Pentyl-3-(1-(4-methoxynaphthoyl) indole)     7081          I
5F-CUMYL-PINACA;SGT-25.............................     7083          I
5F-CUMYL-P7AICA....................................     7085          I
4-CN-CUMYL-BUTINACA................................     7089          I
SR-19 (Also known as RCS-4) (1-Pentyl-3-[(4-            7104          I
 methoxy)-benzoyl] indole..........................
JWH-018 (also known as AM678) (1-Pentyl-3-(1-           7118          I
 naphthoyl)indole).................................
JWH-122 (1-Pentyl-3-(4-methyl-1-naphthoyl) indole).     7122          I
UR-144 (1-Pentyl-1H-indol-3-yl)(2,2,3,3-                7144          I
 tetramethylcyclopropyl)methanone..................
JWH-073 (1-Butyl-3-(1-naphthoyl)indole)............     7173          I
JWH-200 (1-[2-(4-Morpholinyl)ethyl]-3-(1-               7200          I
 naphthoyl)indole).................................
AM2201 (1-(5-Fluoropentyl)-3-(1-naphthoyl) indole).     7201          I
JWH-203 (1-Pentyl-3-(2-chlorophenylacetyl) indole).     7203          I
NM2201.............................................     7221          I
PB-22 (Quinolin-8-yl 1-pentyl-1H-indole-3-              7222          I
 carboxylate)......................................
5F-PB-22 (Quinolin-8-yl 1-(5-fluoropentyl)-1H-          7225          I
 indole-3-carboxylate).............................
4-Methyl-Alpha-Ethylaminopentiophennone............     7245          I

[[Page 55495]]

 
N-Ethylhexedrone, its optical, positional and           7246          I
 geometric isomers, salts and salts of isomers.....
Alpha-ethyltryptamine..............................     7249          I
Ibogaine...........................................     7260          I
CP-47,497 (5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-         7297          I
 hydroxycyclohexyl-phenol).........................
CP-47,497 C8 Homologue (5-(1,1-Dimethyloctyl)-2-        7298          I
 [(1R,3S)3-hydroxycyclohexyl-phenol)...............
Lysergic acid diethylamide.........................     7315          I
2,5-Dimethoxy-4-(n)-propylthiophenethylamine (2C-T-     7348          I
 7)................................................
Marihuana..........................................     7360          I
Tetrahydrocannabinols..............................     7370          I
Mescaline..........................................     7381          I
2-(4-Ethylthio-2,5-dimethoxyphenyl) ethanamine (2C-     7385          I
 T-2 ).............................................
3,4,5-Trimethoxyamphetamine........................     7390          I
4-Bromo-2,5-dimethoxyamphetamine...................     7391          I
4-Bromo-2,5-dimethoxyphenethylamine................     7392          I
4-Methyl-2,5-dimethoxyamphetamine..................     7395          I
2,5-Dimethoxyamphetamine...........................     7396          I
JWH-398 (1-Pentyl-3-(4-chloro-1-naphthoyl) indole).     7398          I
2,5-Dimethoxy-4-ethylamphetamine...................     7399          I
3,4-Methylenedioxyamphetamine......................     7400          I
5-Methoxy-3,4-methylenedioxyamphetamine............     7401          I
N-Hydroxy-3,4-methylenedioxyamphetamine............     7402          I
3,4-Methylenedioxy-N-ethylamphetamine..............     7404          I
3,4-Methylenedioxymethamphetamine..................     7405          I
4-Methoxyamphetamine...............................     7411          I
5-Methoxy-N-N-dimethyltryptamine...................     7431          I
Alpha-methyltryptamine.............................     7432          I
Bufotenine.........................................     7433          I
Diethyltryptamine..................................     7434          I
Dimethyltryptamine.................................     7435          I
Psilocybin.........................................     7437          I
Psilocyn...........................................     7438          I
5-Methoxy-N,N-diisopropyltryptamine................     7439          I
4-CHLORO-ALPHA-Pyrrolidinovalerophenone, its            7443          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
4-METHYL-ALPHA-Pyrrolidinohexiophenone, its             7446          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
N-Ethyl-1-phenylcyclohexylamine....................     7455          I
1-(1-Phenylcyclohexyl)pyrrolidine..................     7458          I
1-[1-(2-Thienyl)cyclohexyl]piperidine..............     7470          I
1-[1-(2-Thienyl)cyclohexyl]pyrrolidine.............     7473          I
N-Benzylpiperazine.................................     7493          I
4-Methyl-Alpha-pyrrolidinopropiophenone, its            7498          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
2-(2,5-Dimethoxy-4-methylphenyl) ethanamine (2C-D).     7508          I
2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine (2C-E ).     7509          I
2-(2,5-Dimethoxyphenyl) ethanamine (2C-H)..........     7517          I
2-(4-iodo-2,5-dimethoxyphenyl) ethanamine (2C-I)...     7518          I
2-(4-Chloro-2,5-dimethoxyphenyl) ethanamine (2C-C).     7519          I
2-(2,5-Dimethoxy-4-nitro-phenyl) ethanamine (2C-N).     7521          I
2-(2,5-Dimethoxy-4-(n)-propylphenyl) ethanamine (2C-    7524          I
 P)................................................
2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]               7532          I
 ethanamine (2C-T-4 )..............................
MDPV (3,4-Methylenedioxypyrovalerone)..............     7535          I
2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)     7536          I
 ethanamine (25B-NBOMe)............................
2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-                  7537          I
 methoxybenzyl)ethanamine (25C-NBOMe)..............
2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)      7538          I
 ethanamine (25I-NBOMe)............................
Methylone (3,4-Methylenedioxy-N-methylcathinone)...     7540          I
Butylone, its optical, positional and geometric         7541          I
 isomers, salts and salts of isomers...............
Pentylone, its optical, positional and geometric        7542          I
 isomers, salts and salts of isomers...............
N-Ethylpentylone, or Ephylone......................     7543          I
ALPHA-Pyrrolidinohexanophenone.....................     7544          I
alpha-pyrrolidinopentiophenone ([alpha]-PVP), its       7545          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
alpha-pyrrolidinobutiophenone ([alpha]-PBP), its        7546          I
 optical, positional and geometric isomers, salts
 and salts of isomers..............................
Ethylone...........................................     7547          I
ALPHA-Pyrrolidinoheptaphenone, its optical,             7548          I
 positional and geometric isomers, salts and salts
 of isomers........................................
AM-694 (1-(5-Fluoropentyl)-3-(2-iodobenzoyl)            7694          I
 indole)...........................................
Acetyldihydrocodeine...............................     9051          I
Benzylmorphine.....................................     9052          I
Codeine-N-oxide....................................     9053          I
Desomorphine.......................................     9055          I
Etorphine (except HCl).............................     9056          I
Codeine methylbromide..............................     9070          I
Dihydromorphine....................................     9145          I
Heroin.............................................     9200          I
Morphine-N-oxide...................................     9307          I
Normorphine........................................     9313          I
U-47700 (3,4-dichloro-N-[2-                             9547          I
 (dimethylamino)cyclohexyl]-N-methylbenzamide).....

[[Page 55496]]

 
AH-7921............................................     9551          I
MT-45 (1-cyclohexyl-4-(1,2-                             9560          I
 diphenylethyl)piperazine))........................
Etonitazene........................................     9624          I
Ketobemidone.......................................     9628          I
Tilidine...........................................     9750          I
Acryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-        9811          I
 phenylacrylamide).................................
Para-Fluorofentanyl................................     9812          I
3-Methylfentanyl...................................     9813          I
Alpha-methylfentanyl...............................     9814          I
Acetyl-alpha-methylfentanyl........................     9815          I
N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-           9816          I
 yl)propionamide...................................
Acetyl Fentanyl (N-(1-phenethylpiperidin-4-yl)-N-       9821          I
 phenylacetamide)..................................
Butyryl Fentanyl...................................     9822          I
Para-fluorobutyryl fentanyl........................     9823          I
4-Fluoroisobutyryl fentanyl (N-(4-fluorophenyl)-N-      9824          I
 (1phenethylpiperidin-4-yl)isobutyramide)..........
2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-              9825          I
 phenylacetamide...................................
Para-chloroisobutyryl fentanyl.....................     9826          I
Isobutyryl fentanyl................................     9827          I
Beta-hydroxyfentanyl...............................     9830          I
Beta-hydroxy-3-methylfentanyl......................     9831          I
Alpha-methylthiofentanyl...........................     9832          I
3-Methylthiofentanyl...............................     9833          I
Furanyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-      9834          I
 phenylfuran-2-carboxamide)........................
Thiofentanyl.......................................     9835          I
Beta-hydroxythiofentanyl...........................     9836          I
Para-methoxybutyryl fentanyl.......................     9837          I
Ocfentanil.........................................     9838          I
Valeryl fentanyl...................................     9840          I
N-(1-phenethylpiperidin-4-yl)-N-                        9843          I
 phenyltetrahydrofuran-2-carboxamide...............
Cyclopropyl Fentanyl...............................     9845          I
Cyclopentyl fentanyl...............................     9847          I
Fentanyl related-compounds as defined in 21 CFR         9850          I
 1308.11(h)........................................
Amphetamine........................................     1100         II
Methamphetamine....................................     1105         II
Lisdexamfetamine...................................     1205         II
Phenmetrazine......................................     1631         II
Methylphenidate....................................     1724         II
Amobarbital........................................     2125         II
Pentobarbital......................................     2270         II
Secobarbital.......................................     2315         II
Glutethimide.......................................     2550         II
1-Phenylcyclohexylamine............................     7460         II
Phencyclidine......................................     7471         II
4-Anilino-N-phenethyl-4-piperidine (ANPP)..........     8333         II
Norfentanyl........................................     8366         II
Phenylacetone......................................     8501         II
1-Piperidinocyclohexanecarbonitrile................     8603         II
Cocaine............................................     9041         II
Codeine............................................     9050         II
Etorphine HCl......................................     9059         II
Dihydrocodeine.....................................     9120         II
Oxycodone..........................................     9143         II
Hydromorphone......................................     9150         II
Ecgonine...........................................     9180         II
Ethylmorphine......................................     9190         II
Hydrocodone........................................     9193         II
Levomethorphan.....................................     9210         II
Levorphanol........................................     9220         II
Isomethadone.......................................     9226         II
Meperidine.........................................     9230         II
Meperidine intermediate-B..........................     9233         II
Methadone..........................................     9250         II
Dextropropoxyphene, bulk (non-dosage forms)........     9273         II
Morphine...........................................     9300         II
Thebaine...........................................     9333         II
Oxymorphone........................................     9652         II
Thiafentanil.......................................     9729         II
Alfentanil.........................................     9737         II
Remifentanil.......................................     9739         II
Sufentanil.........................................     9740         II
Carfentanil........................................     9743         II
Tapentadol.........................................     9780         II
Fentanyl...........................................     9801         II
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[[Page 55497]]

    The company plans to bulk manufacture the listed controlled 
substances to produce forensic and research of analytical reference 
standards for distribution to its customers. In reference to Marihuana 
(7360) and Tetrahydrocannabinols (7370) the company will manufacture as 
synthetics only. No other activities for these drug codes are 
authorized for this registration.

William T. McDermott,
Assistant Administrator.
[FR Doc. 2020-19805 Filed 9-4-20; 8:45 am]
BILLING CODE 4410-09-P