[Federal Register Volume 84, Number 179 (Monday, September 16, 2019)]
[Notices]
[Page 48630]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-19951]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: The inventions listed below are owned by an agency of the U.S. 
Government and are available for licensing in the U.S. to achieve 
expeditious commercialization of results of federally-funded research 
and development.

FOR FURTHER INFORMATION CONTACT: Licensing information may be obtained 
by emailing the indicated licensing contact at the National Heart, 
Lung, and Blood, Office of Technology Transfer and Development Office 
of Technology Transfer, 31 Center Drive Room 4A29, MSC2479, Bethesda, 
MD 20892-2479; telephone: 301-402-5579. A signed Confidential 
Disclosure Agreement may be required to receive any unpublished 
information.

SUPPLEMENTARY INFORMATION: Technology description follows.

PET Imaging of fungal infections

    Available for licensing and commercial development are patent 
rights covering a PET imaging method for fungal infections, for 
example, Aspergillus fumigatus. Currently, there is a lack of imaging 
agents specific for fungal infections. L-Rhamnose is selectively 
uptaken by live A. fumigatus. PET imaging experiments showed a 39% 
increase in uptake by infected mice as opposed to control mice when 
administered 18F-deoxyrhamnose. As such, the instant imaging agent has 
potential as a fungal infection diagnostic imaging agent.
    Potential Commercial Applications:

 Imaging of live fungal infections
 Imaging of live infections of A. fumigatus

    Development Stage:

 Preclinical
 Mouse data
    Inventors: Dima Hammoud (NIHCC), Rolf Swenson (NHLBI), Xiang (Sean) 
Zhang (NHLBI), Swati Shah (CC) and Peter Richard Williamson (NIAID).
    Intellectual Property: HHS Reference No. E-163-2019-0-US-01 ; U.S 
Patent Applications 62/882,023 filed August 2, 2019; Klarquist Ref. No. 
4239-103017-01.
    Licensing Contact: Michael Shmilovich, Esq, CLP; 301-435-5019; 
[email protected].

    Dated: September 3, 2019.
Michael A. Shmilovich,
Senior Licensing and Patenting Manager, National Heart, Lung, and Blood 
Institute, Office of Technology Transfer and Development.
[FR Doc. 2019-19951 Filed 9-13-19; 8:45 am]
 BILLING CODE 4140-01-P