[Federal Register Volume 84, Number 165 (Monday, August 26, 2019)]
[Notices]
[Pages 44637-44639]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-18322]


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DEPARTMENT OF JUSTICE

Drug Enforcement Administration

[Docket No. DEA-392]


Bulk Manufacturer of Controlled Substances Application: Cayman 
Chemical Company

ACTION: Notice of application.

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DATES: Registered bulk manufacturers of the affected basic classes, and 
applicants therefore, may file written comments on or objections to the 
issuance of the proposed registration on or before October 25, 2019.

ADDRESSES:  Written comments should be sent to: Drug Enforcement 
Administration, Attention: DEA Federal Register Representative/DRW, 
8701 Morrissette Drive, Springfield, Virginia 22152.

SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 1301.33(a), this 
is notice that on July 25, 2018, Cayman Chemical Company, 1180 East 
Ellsworth Road, Ann Arbor, Michigan 48108 applied to be registered as a 
bulk manufacturer of the following basic classes of controlled 
substances:

------------------------------------------------------------------------
                                           Drug
          Controlled substance             code          Schedule
------------------------------------------------------------------------
3-Fluoro-N-methylcathinone (3-FMC).....     1233  I
Cathinone..............................     1235  I
Methcathinone..........................     1237  I
4-Fluoro-N-methylcathinone (4-FMC).....     1238  I
Pentedrone ([alpha]-                        1246  I
 methylaminovalerophenone).
Mephedrone (4-Methyl-N-methylcathinone)     1248  I
4-Methyl-N-ethylcathinone (4-MEC)......     1249  I
Naphyrone..............................     1258  I
N-Ethylamphetamine.....................     1475  I
N,N-Dimethylamphetamine................     1480  I
Fenethylline...........................     1503  I
Aminorex...............................     1585  I
4-Methylaminorex (cis isomer)..........     1590  I
Gamma Hydroxybutyric Acid..............     2010  I
Methaqualone...........................     2565  I
Mecloqualone...........................     2572  I
JWH-250 (1-Pentyl-3-(2-                     6250  I
 methoxyphenylacetyl) indole).
SR-18 (Also known as RCS-8) (1-             7008  I
 Cyclohexylethyl-3-(2-
 methoxyphenylacetyl) indole).
ADB-FUBINACA (n-(1-amino-3,3-dimethyl-1-    7010  I
 oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-
 indazole-3-carboxamide).
5-Flouro-UR-144 and XLR11 [1-(5-Fluoro-     7011  I
 pentyl)1H-indol-3-yl](2,2,3,3-
 tetramethylcyclopropyl)methanone.
AB-FUBINACA (N-(1-amino-3-methyl-1-         7012  I
 oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-
 indazole-3-carboxamide).
JWH-019 (1-Hexyl-3-(1-naphthoyl)indole)     7019  I
MDMB-FUBINACA (Methyl 2-(1-4-               7020  I
 fluorobenzyl)-1H-indazole-3-
 carboxamido)-3,3-dimethylbutanoate).
2-(1-(4-fluorobenzyl)-1Hindazole-3-         7021  I
 carboxamido)-3-methylbutanoate.
AB-PINACA (N-(1-amino-3-methyl-1-           7023  I
 oxobutan-2-yl)-1-pentyl-1H-indazole-3-
 carboxamide).
THJ-2201 [1-(5-fluoropentyl)-1H-indazol-    7024  I
 3-yl](naphthalen-1-yl)methanone.
AB-CHMINACA (N-(1-amino-3-methyl-1-         7031  I
 oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-
 indazole-3-carboxamide.
MAB-CHMINACA (N-(1-amino-3,3dimethyl-1-     7032  I
 oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-
 indazole-3-carboxamide).
5F-AMB (Methyl 2-(1-(5-fluoropentyl)-1H-    7033  I
 indazola-3-carboxamido)-3-
 methylbutanoate).
5F-ADB; 5F-MDMB-PINACA (Methyl 2-(1-        7034  I
 (5fluoropentyl)-1H-indazole-3-
 carboxamido)-3,3dimethylbutanoate).
ADB-PINACA (N-(1-amino-3,3-dimethyl-1-      7035  I
 oxobutan-2-yl)-1-pentyl-1H-indazole-3-
 carboxamide).
MDMB-CHMICA, MMB-CHMINACA (Methyl 2-(1-     7042  I
 (cyclohenxylmethyl)-1H-indole-3-
 carboxamido)-3,3-dimethylbutanote)-.
APINACA and AKB48 N-(1-Adamantyl)-1-        7048  I
 pentyl-1H-indazole-3-carboxamide.
5F-APINACA, 5F-AKB48 (N-(adamantan-1-       7049  I
 yl)-1-(5fluoropentyl)-1H-indazole-3-
 carboxamide).
JWH-081 (1-Pentyl-3-(1-(4-                  7081  I
 methoxynaphthoyl) indole).
SR-19 (Also known as RCS-4) (1-Pentyl-3-    7104  I
 [(4-methoxy)-benzoyl] indole.
JWH-018 (also known as AM678) (1-Pentyl-    7118  I
 3-(1-naphthoyl)indole).
JWH-122 (1-Pentyl-3-(4-methyl-1-            7122  I
 naphthoyl) indole).
UR-144 (1-Pentyl-1H-indol-3-yl)(2,2,3,3-    7144  I
 tetramethylcyclopropyl)methanone.
JWH-073 (1-Butyl-3-(1-naphthoyl)indole)     7173  I
JWH-200 (1-[2-(4-Morpholinyl)ethyl]-3-      7200  I
 (1-naphthoyl)indole).
AM2201 (1-(5-Fluoropentyl)-3-(1-            7201  I
 naphthoyl) indole).
JWH-203 (1-Pentyl-3-(2-                     7203  I
 chlorophenylacetyl) indole).
PB-22 (Quinolin-8-yl 1-pentyl-1H-indole-    7222  I
 3-carboxylate).
5F-PB-22 (Quinolin-8-yl 1-(5-               7225  I
 fluoropentyl)-1H-indole-3-carboxylate).
Alpha-ethyltryptamine..................     7249  I
Ibogaine...............................     7260  I

[[Page 44638]]

 
CP-47,497 (5-(1,1-Dimethylheptyl)-2-        7297  I
 [(1R,3S)-3-hydroxycyclohexyl-phenol).
CP-47,497 C8 Homologue (5-(1,1-             7298  I
 Dimethyloctyl)-2-[(1R,3S)3-
 hydroxycyclohexyl-phenol).
Lysergic acid diethylamide.............     7315  I
2,5-Dimethoxy-4-(n)-                        7348  I
 propylthiophenethylamine (2C-T-7).
Marihuana..............................     7360  I
Tetrahydrocannabinols..................     7370  I
Mescaline..............................     7381  I
2-(4-Ethylthio-2,5-dimethoxyphenyl)         7385  I
 ethanamine (2C-T-2 ).
3,4,5-Trimethoxyamphetamine............     7390  I
4-Bromo-2,5-dimethoxyamphetamine.......     7391  I
4-Bromo-2,5-dimethoxyphenethylamine....     7392  I
4-Methyl-2,5-dimethoxyamphetamine......     7395  I
2,5-Dimethoxyamphetamine...............     7396  I
JWH-398 (1-Pentyl-3-(4-chloro-1-            7398  I
 naphthoyl) indole).
2,5-Dimethoxy-4-ethylamphetamine.......     7399  I
3,4-Methylenedioxyamphetamine..........     7400  I
5-Methoxy-3,4-methylenedioxyamphetamine     7401  I
N-Hydroxy-3,4-methylenedioxyamphetamine     7402  I
3,4-Methylenedioxy-N-ethylamphetamine..     7404  I
3,4-Methylenedioxymethamphetamine......     7405  I
4-Methoxyamphetamine...................     7411  I
5-Methoxy-N-N-dimethyltryptamine.......     7431  I
Alpha-methyltryptamine.................     7432  I
Diethyltryptamine......................     7434  I
Dimethyltryptamine.....................     7435  I
Psilocybin.............................     7437  I
Psilocyn...............................     7438  I
5-Methoxy-N,N-diisopropyltryptamine....     7439  I
N-Ethyl-1-phenylcyclohexylamine........     7455  I
1-(1-Phenylcyclohexyl)pyrrolidine......     7458  I
1-[1-(2-Thienyl)cyclohexyl]piperidine..     7470  I
1-[1-(2-Thienyl)cyclohexyl]pyrrolidine.     7473  I
N-Benzylpiperazine.....................     7493  I
2-(2,5-Dimethoxy-4-methylphenyl)            7508  I
 ethanamine (2C-D).
2-(2,5-Dimethoxy-4-ethylphenyl)             7509  I
 ethanamine (2C-E ).
2-(2,5-Dimethoxyphenyl) ethanamine (2C-     7517  I
 H).
2-(4-iodo-2,5-dimethoxyphenyl)              7518  I
 ethanamine (2C-I).
2-(4-Chloro-2,5-dimethoxyphenyl)            7519  I
 ethanamine (2C-C).
2-(2,5-Dimethoxy-4-nitro-phenyl)            7521  I
 ethanamine (2C-N).
2-(2,5-Dimethoxy-4-(n)-propylphenyl)        7524  I
 ethanamine (2C-P).
2-(4-Isopropylthio)-2,5-                    7532  I
 dimethoxyphenyl) ethanamine (2C-T-4 ).
MDPV (3,4-Methylenedioxypyrovalerone)..     7535  I
2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-       7536  I
 methoxybenzyl) ethanamine (25B-NBOMe).
2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-      7537  I
 methoxybenzyl) ethanamine (25C-NBOMe).
2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-        7538  I
 methoxybenzyl) ethanamine (25I-NBOMe).
Methylone (3,4-Methylenedioxy-N-            7540  I
 methylcathinone).
Butylone...............................     7541  I
Pentylone..............................     7542  I
alpha-pyrrolidinopentiophenone ([alpha]-    7545  I
 PVP).
alpha-pyrrolidinobutiophenone ([alpha]-     7546  I
 PBP).
AM-694 (1-(5-Fluoropentyl)-3-(2-            7694  I
 iodobenzoyl) indole).
Acetyldihydrocodeine...................     9051  I
Benzylmorphine.........................     9052  I
Codeine-N-oxide........................     9053  I
Desomorphine...........................     9055  I
Etorphine (except HCl).................     9056  I
Codeine methylbromide..................     9070  I
Dihydromorphine........................     9145  I
Heroin.................................     9200  I
Morphine-N-oxide.......................     9307  I
Normorphine............................     9313  I
U-47700 (3,4-dichloro-N-[2-                 9547  I
 (dimethylamino)cyclohexyl]-N-
 methylbenzamide).
MT-45 (1-cyclohexyl-4-(1,2-                 9560  I
 diphenylethyl)piperazine)).
Tilidine...............................     9750  I
Acryl fentanyl (N-(1-phenethylpiperidin-    9811  I
 4-yl)-N-phenylacrylamide).
Para-Fluorofentanyl....................     9812  I
3-Methylfentanyl.......................     9813  I
Alpha-methylfentanyl...................     9814  I
Acetyl-alpha-methylfentanyl............     9815  I
N-(2-fluorophenyl)-N-(1-                    9816  I
 phenethylpiperidin-4-yl)propionamide.
Acetyl Fentanyl (N-(1-                      9821  I
 phenethylpiperidin-4-yl)-N-
 phenylacetamide).
Butyryl Fentanyl.......................     9822  I
Para-fluorobutyryl fentanyl............     9823  I

[[Page 44639]]

 
4-Fluoroisobutyryl fentanyl (N-(4-          9824  I
 fluorophenyl)-N-(1phenethylpiperidin-4-
 yl)isobutyramide).
2-methoxy-N-(1-phenethylpiperidin-4-yl)-    9825  I
 N-phenylacetamide.
Para-chloroisobutyryl fentanyl.........     9826  I
Isobutyryl fentanyl....................     9827  I
Beta-hydroxyfentanyl...................     9830  I
Beta-hydroxy-3-methylfentanyl..........     9831  I
Alpha-methylthiofentanyl...............     9832  I
3-Methylthiofentanyl...................     9833  I
Furanyl fentanyl (N-(1-                     9834  I
 phenethylpiperidin-4-yl)-N-phenylfuran-
 2-carboxamide).
Thiofentanyl...........................     9835  I
Beta-hydroxythiofentanyl...............     9836  I
Para-methoxybutyryl fentanyl...........     9837  I
Ocfentanil.............................     9838  I
Valeryl fentanyl.......................     9840  I
N-(1-phenethylpiperidin-4-yl)-N-            9843  I
 phenyltetrahydrofuran-2-carboxamide.
Cyclopropyl Fentanyl...................     9845  I
Cyclopentyl fentanyl...................     9847  I
Fentanyl related-compounds as defined       9850  I
 in 21 CFR 1308.11(h).
Amphetamine............................     1100  II
Methamphetamine........................     1105  II
Lisdexamfetamine.......................     1205  II
Phenmetrazine..........................     1631  II
Methylphenidate........................     1724  II
Amobarbital............................     2125  II
Pentobarbital..........................     2270  II
Secobarbital...........................     2315  II
Phencyclidine..........................     7471  II
4-Anilino-N-phenethyl-4-piperidine          8333  II
 (ANPP).
Phenylacetone..........................     8501  II
1-Piperidinocyclohexanecarbonitrile....     8603  II
Cocaine................................     9041  II
Codeine................................     9050  II
Etorphine HCl..........................     9059  II
Dihydrocodeine.........................     9120  II
Oxycodone..............................     9143  II
Hydromorphone..........................     9150  II
Ecgonine...............................     9180  II
Ethylmorphine..........................     9190  II
Hydrocodone............................     9193  II
Levomethorphan.........................     9210  II
Levorphanol............................     9220  II
Isomethadone...........................     9226  II
Meperidine.............................     9230  II
Meperidine intermediate-B..............     9233  II
Methadone..............................     9250  II
Dextropropoxyphene, bulk (non-dosage        9273  II
 forms).
Morphine...............................     9300  II
Thebaine...............................     9333  II
Oxymorphone............................     9652  II
Thiafentanil...........................     9729  II
Alfentanil.............................     9737  II
Remifentanil...........................     9739  II
Sufentanil.............................     9740  II
Carfentanil............................     9743  II
Tapentadol.............................     9780  II
Fentanyl...............................     9801  II
------------------------------------------------------------------------

    The company plans to bulk manufacture the listed controlled 
substances to produce forensic and research of analytical reference 
standards for distribution to its customers. In reference to marihuana 
(7360) and tetrahydrocannabinols (7370) the company will manufacture as 
synthetics only. No other activities for these drug codes are 
authorized for this registration.

    Dated: August 9, 2019.
Neil D. Doherty,
Acting Assistant Administrator.
[FR Doc. 2019-18322 Filed 8-23-19; 8:45 am]
 BILLING CODE 4410-09-P