[Federal Register Volume 84, Number 90 (Thursday, May 9, 2019)]
[Notices]
[Pages 20359-20360]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-09538]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[Docket No. ATSDR-2019-0006]


Availability of Draft Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice with comment period.

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SUMMARY: The Agency for Toxic Substances and Disease Registry (ATSDR), 
within the Department of Health and Human Services (HHS), announces the 
opening of a docket to obtain comments on Draft Toxicological Profiles 
for Dinitrophenols, 2-Butanone, Mirex and Chlordecone, 1,2-
Diphenylhydrazine, 1,2,3-Trichloropropane, Lead, and Endrin. ATSDR has 
updated these profiles based on availability of new health effects 
information since their initial release. On March 21, 2016 ATSDR 
announced that it was preparing to develop Draft Toxicological Profiles 
for public comment release (81 FR 15110), which include those profiles 
mentioned above. All toxicological profiles issued as ``Drafts for 
Public Comment'' represent the result of ATSDR's evidence-based 
evaluations to provide important toxicological information on priority 
hazardous substances. ATSDR is seeking public comments and additional 
information or reports on studies about the health effects of 
dinitrophenols, 2-butanone, mirex and chlordecone, 1,2-
diphenylhydrazine, 1,2,3-trichloropropane, lead, and endrin for review 
and potential inclusion in the profiles. ATSDR considers key studies 
for these substances during the profile development process. This 
document solicits any relevant, additional studies. ATSDR will evaluate 
the quality and relevance of such data or studies for possible 
inclusion into the profile.

DATES: Written comments must be received on or before August 7, 2019.

ADDRESSES: You may submit comments, identified by docket number ATSDR-
2019-0006, by any of the following methods:
     Federal eRulemaking Portal: www.regulations.gov. Follow 
the instructions for submitting comments.
     Mail: Division of Toxicology and Human Health Sciences, 
Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd. NE, 
Mail Stop S102-1, Atlanta, GA, 30329-4027. Attn: Docket No. ATSDR-2019-
0006.
    Instructions: All submissions must include the agency name and 
Docket Number. All relevant comments received will be posted without 
change to http://regulations.gov, including any personal information 
provided. For access to the docket to read background documents or 
comments received, go to http://www.regulations.gov.

FOR FURTHER INFORMATION CONTACT: Susan Ingber, Agency for Toxic 
Substances and Disease Registry, Division of Toxicology and Human 
Health Sciences, 1600 Clifton Rd. NE, Mail Stop S102-1, Atlanta, GA, 
30329-4027, Email: [email protected]; Phone: 1-800-232-4636.

SUPPLEMENTARY INFORMATION:

Public Participation

    Interested persons or organizations are invited to participate by 
submitting written views, information, and data.
    Please note that comments received, including attachments and other 
supporting materials, are part of the public record and are subject to 
public disclosure. Comments will be posted on https://www.regulations.gov. Therefore, do not include any information in your 
comment or supporting materials that you consider confidential or 
inappropriate for public disclosure. If you include your name, contact 
information, or other information that identifies you in the body of 
your comments, that information will be on public display. ATSDR will 
review all submissions and may choose to redact, or withhold, 
submissions containing private or proprietary information such as 
Social Security numbers, medical information, inappropriate language, 
or duplicate/near duplicate examples of a mass-mail campaign. ATSDR 
will carefully consider all comments submitted in preparation of the 
final Toxicological Profiles and may revise the profiles as 
appropriate.

Legislative Background

    The Superfund Amendments and Reauthorization Act of 1986 (SARA) [42

[[Page 20360]]

U.S.C. 9601 et seq.] amended the Comprehensive Environmental Response, 
Compensation, and Liability Act of 1980 (CERCLA or Superfund) [42 
U.S.C. 9601 et seq.] by establishing certain requirements for ATSDR and 
the U.S. Environmental Protection Agency (EPA) regarding hazardous 
substances that are most commonly found at facilities on the CERCLA 
National Priorities List (NPL). Among these statutory requirements is a 
mandate for the Administrator of ATSDR to prepare toxicological 
profiles for each substance included on the priority list of hazardous 
substances [also called the Substance Priority List (SPL)]. This list 
identifies 275 hazardous substances that ATSDR and EPA have determined 
pose the most significant potential threat to human health. The SPL is 
available online at www.atsdr.cdc.gov/spl.
    In addition, CERCLA provides ATSDR with the authority to prepare 
toxicological profiles for substances not found on the SPL. CERCLA 
authorizes ATSDR to establish and maintain an inventory of literature, 
research, and studies on the health effects of toxic substances (CERCLA 
Section 104(i)(1)(B); 42 U.S.C. 9604(i)(1)(B)); to respond to requests 
for health consultations (CERCLA Section 104(i)(4); 42 U.S.C. 
9604(i)(4)); and to support the site-specific response actions 
conducted by the agency.

Availability

    These Draft Toxicological Profiles will be available online at 
http://www.atsdr.cdc.gov/ToxProfiles and at www.regulations.gov, Docket 
No. ATSDR-2019-0006.

Pamela I. Protzel Berman,
Director, Office of Policy, Partnerships and Planning, Agency for Toxic 
Substances and Disease Registry.
[FR Doc. 2019-09538 Filed 5-8-19; 8:45 am]
 BILLING CODE 4163-70-P