[Federal Register Volume 84, Number 51 (Friday, March 15, 2019)]
[Notices]
[Pages 9524-9525]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-04794]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[Docket Number CDC-2019-0015, NIOSH-153-E]
Request for the Technical Review of 10 Draft Skin Notation
Assignments and Skin Notation Profiles
AGENCY: National Institute for Occupational Safety and Health (NIOSH)
of the Centers for Disease Control and Prevention (CDC), Department of
Health and Human Services (HHS).
ACTION: Request for information and comment.
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SUMMARY: The National Institute for Occupational Safety and Health of
the Centers for Disease Control and Prevention announces the
availability of 10 draft skin notation profile documents now available
for public comment entitled:
Skin notation profile: Cyclohexanol
Skin notation profile: Cyclohexanone
Skin notation profile: Cyclonite
Skin notation profile: Diacetyl and 2,3-Pentanedione
Skin notation profile: Diethylenetriamine
Skin notation profile: beta-Chloroprene
Skin notation profile: Chlorodiphenyl 42% Chlorine
Skin notation profile: Chlorodiphenyl 54% Chlorine
Skin notation profile: Dioxane
Skin notation profile: 2,4-Toluene diisocyanate, 2,6-Toluene
diisocyanate, and the mixture of 2,4- and 2,6-Toluene diisocyanate
To view the notice and related materials, visit https://www.regulations.gov and enter CDC-2019-0015 in the search field and
click ``Search.''
DATES: Electronic or written comments must be received by May 14, 2019.
ADDRESSES: You may submit comments, identified by CDC-2019-0015 and
docket number NIOSH-153-E, by any of the following methods:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments.
Mail: National Institute for Occupational Safety and
Health, NIOSH Docket Office, 1090 Tusculum Avenue, MS C-34, Cincinnati,
Ohio 45226-1998.
Instructions: All information received in response to this notice
must include the agency name and docket number [CDC-2019-0015; NIOSH-
153-E]. All relevant comments received will be posted without change to
https://www.regulations.gov, including any personal information
provided. All electronic comments should be formatted as Microsoft
Word. For access to the docket to read background documents or comments
received, go to https://www.regulations.gov. All information received
in response to this notice will also be available for public
examination and copying at the NIOSH Docket Office, 1150 Tusculum
Avenue, Room 155, Cincinnati, OH 45226-1998.
FOR FURTHER INFORMATION CONTACT: Naomi Hudson, NIOSH/EID, Robert A.
Taft Laboratories, 1090 Tusculum Avenue, MS-C32, Cincinnati, OH 45226.
Telephone: (513) 533-8388 (not a toll free number).
SUPPLEMENTARY INFORMATION: The National Institute for Occupational
Safety and Health (NIOSH) of the Centers for Disease Control and
Prevention (CDC) is conducting a public review of the draft skin
notations and support technical documents, entitled Skin Notations
Profiles, for 10 chemicals. NIOSH is requesting technical reviews of
the draft Skin Notation Profiles.
Background: In 2009, NIOSH published Current Intelligence Bulletin
(CIB) 61--A Strategy for Assigning New NIOSH Skin Notations [NIOSH
2009-147; http://www.cdc.gov/niosh/docs/2009-147/pdfs/2009-147.pdf].
The CIB presents a strategic framework that is a form of hazard
identification designed to do the following:
1. Ensure that the assigned skin notations reflect the contemporary
state of scientific knowledge.
2. Provide transparency behind the assignment process.
3. Communicate the hazards of chemical exposures of the skin.
4. Meet the needs of health professionals, employers, and other
interested parties in protecting workers from chemical contact with the
skin.
This strategy involves the assignment of multiple skin notations for
distinguishing systemic (SYS), direct (DIR), and sensitizing (SEN)
effects caused by exposure of skin (SK) to chemicals.
Information Needs: To facilitate the review of these documents,
NIOSH requests that the following questions be taken into
consideration:
1. Does this document clearly outline the systemic health hazards
associated with exposures of the skin to the chemical? If not, what
specific information is missing from the document?
2. If the SYS or SYS (FATAL) notations are assigned, are the
rationale
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and logic behind the assignment clear? If not assigned, is the logic
clear why it was not (e.g., insufficient data, no identified health
hazard)?
3. Does this document clearly outline the direct (localized) health
hazards associated with exposures of the skin to the chemical? If not,
what specific information is missing from the document?
4. If the DIR, DIR (IRR), or DIR (COR) notations are assigned, are
the rationale and logic behind the assignment clear? If not assigned,
is the logic clear why it was not (e.g., insufficient data, no
identified health hazard)?
5. Does this document clearly outline the immune-mediated responses
(allergic response) as health hazards associated with exposures of the
skin to the chemical? If not, what specific information is missing from
the document?
6. If the SEN notation is assigned, are the rationale and logic
behind the assignment clear? If not assigned, is the logic clear why it
was not (e.g., insufficient data, no identified health hazard)?
7. If the ID (SK) or SK were assigned, are the rationale and logic
outlined within the document?
8. Are the conclusions supported by the data?
9. Are the tables clear and appropriate?
10. Is the document organized appropriately? If not, what
improvements are needed?
11. Are you aware of any scientific data reported in governmental
publications, databases, peer-reviewed journals, or other sources that
should be included within this document?
References:
Current Intelligence Bulletin 61: A Strategy for Assigning New NIOSH
Skin Notations [https://www.cdc.gov/niosh/docs/2009-147/]
Dated: March 11, 2019.
Frank J. Hearl,
Chief of Staff, National Institute for Occupational Safety and Health,
Centers for Disease Control and Prevention.
[FR Doc. 2019-04794 Filed 3-14-19; 8:45 am]
BILLING CODE 4163-19-P