[Federal Register Volume 84, Number 51 (Friday, March 15, 2019)]
[Notices]
[Pages 9524-9525]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-04794]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[Docket Number CDC-2019-0015, NIOSH-153-E]


Request for the Technical Review of 10 Draft Skin Notation 
Assignments and Skin Notation Profiles

AGENCY: National Institute for Occupational Safety and Health (NIOSH) 
of the Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (HHS).

ACTION: Request for information and comment.

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SUMMARY: The National Institute for Occupational Safety and Health of 
the Centers for Disease Control and Prevention announces the 
availability of 10 draft skin notation profile documents now available 
for public comment entitled:

Skin notation profile: Cyclohexanol
Skin notation profile: Cyclohexanone
Skin notation profile: Cyclonite
Skin notation profile: Diacetyl and 2,3-Pentanedione
Skin notation profile: Diethylenetriamine
Skin notation profile: beta-Chloroprene
Skin notation profile: Chlorodiphenyl 42% Chlorine
Skin notation profile: Chlorodiphenyl 54% Chlorine
Skin notation profile: Dioxane
Skin notation profile: 2,4-Toluene diisocyanate, 2,6-Toluene 
diisocyanate, and the mixture of 2,4- and 2,6-Toluene diisocyanate
To view the notice and related materials, visit https://www.regulations.gov and enter CDC-2019-0015 in the search field and 
click ``Search.''

DATES: Electronic or written comments must be received by May 14, 2019.

ADDRESSES: You may submit comments, identified by CDC-2019-0015 and 
docket number NIOSH-153-E, by any of the following methods:
     Federal eRulemaking Portal: https://www.regulations.gov. 
Follow the instructions for submitting comments.
     Mail: National Institute for Occupational Safety and 
Health, NIOSH Docket Office, 1090 Tusculum Avenue, MS C-34, Cincinnati, 
Ohio 45226-1998.
    Instructions: All information received in response to this notice 
must include the agency name and docket number [CDC-2019-0015; NIOSH-
153-E]. All relevant comments received will be posted without change to 
https://www.regulations.gov, including any personal information 
provided. All electronic comments should be formatted as Microsoft 
Word. For access to the docket to read background documents or comments 
received, go to https://www.regulations.gov. All information received 
in response to this notice will also be available for public 
examination and copying at the NIOSH Docket Office, 1150 Tusculum 
Avenue, Room 155, Cincinnati, OH 45226-1998.

FOR FURTHER INFORMATION CONTACT: Naomi Hudson, NIOSH/EID, Robert A. 
Taft Laboratories, 1090 Tusculum Avenue, MS-C32, Cincinnati, OH 45226. 
Telephone: (513) 533-8388 (not a toll free number).

SUPPLEMENTARY INFORMATION: The National Institute for Occupational 
Safety and Health (NIOSH) of the Centers for Disease Control and 
Prevention (CDC) is conducting a public review of the draft skin 
notations and support technical documents, entitled Skin Notations 
Profiles, for 10 chemicals. NIOSH is requesting technical reviews of 
the draft Skin Notation Profiles.
    Background: In 2009, NIOSH published Current Intelligence Bulletin 
(CIB) 61--A Strategy for Assigning New NIOSH Skin Notations [NIOSH 
2009-147; http://www.cdc.gov/niosh/docs/2009-147/pdfs/2009-147.pdf]. 
The CIB presents a strategic framework that is a form of hazard 
identification designed to do the following:
    1. Ensure that the assigned skin notations reflect the contemporary 
state of scientific knowledge.
    2. Provide transparency behind the assignment process.
    3. Communicate the hazards of chemical exposures of the skin.
    4. Meet the needs of health professionals, employers, and other 
interested parties in protecting workers from chemical contact with the 
skin.

This strategy involves the assignment of multiple skin notations for 
distinguishing systemic (SYS), direct (DIR), and sensitizing (SEN) 
effects caused by exposure of skin (SK) to chemicals.
    Information Needs: To facilitate the review of these documents, 
NIOSH requests that the following questions be taken into 
consideration:
    1. Does this document clearly outline the systemic health hazards 
associated with exposures of the skin to the chemical? If not, what 
specific information is missing from the document?
    2. If the SYS or SYS (FATAL) notations are assigned, are the 
rationale

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and logic behind the assignment clear? If not assigned, is the logic 
clear why it was not (e.g., insufficient data, no identified health 
hazard)?
    3. Does this document clearly outline the direct (localized) health 
hazards associated with exposures of the skin to the chemical? If not, 
what specific information is missing from the document?
    4. If the DIR, DIR (IRR), or DIR (COR) notations are assigned, are 
the rationale and logic behind the assignment clear? If not assigned, 
is the logic clear why it was not (e.g., insufficient data, no 
identified health hazard)?
    5. Does this document clearly outline the immune-mediated responses 
(allergic response) as health hazards associated with exposures of the 
skin to the chemical? If not, what specific information is missing from 
the document?
    6. If the SEN notation is assigned, are the rationale and logic 
behind the assignment clear? If not assigned, is the logic clear why it 
was not (e.g., insufficient data, no identified health hazard)?
    7. If the ID (SK) or SK were assigned, are the rationale and logic 
outlined within the document?
    8. Are the conclusions supported by the data?
    9. Are the tables clear and appropriate?
    10. Is the document organized appropriately? If not, what 
improvements are needed?
    11. Are you aware of any scientific data reported in governmental 
publications, databases, peer-reviewed journals, or other sources that 
should be included within this document?

References:

Current Intelligence Bulletin 61: A Strategy for Assigning New NIOSH 
Skin Notations [https://www.cdc.gov/niosh/docs/2009-147/]

    Dated: March 11, 2019.
Frank J. Hearl,
Chief of Staff, National Institute for Occupational Safety and Health, 
Centers for Disease Control and Prevention.
[FR Doc. 2019-04794 Filed 3-14-19; 8:45 am]
 BILLING CODE 4163-19-P