[Federal Register Volume 81, Number 213 (Thursday, November 3, 2016)]
[Notices]
[Page 76621]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-26604]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Announcement of Availability of the Fourteenth Report on 
Carcinogens

SUMMARY: The Department of Health and Human Services released the 14th 
Report on Carcinogens (RoC) to the public on November 3, 2016. The 
report is available on the RoC Web site at: http://ntp.niehs.nih.gov/go/roc or from the Office of the RoC (see ADDRESSES).

DATES: The 14th RoC is available to the public on November 3, 2016.

ADDRESSES: Dr. Ruth Lunn, Director, Office of the RoC, National 
Toxicology Program (NTP), National Institute of Environmental Health 
Sciences (NIEHS), P.O. Box 12233, MD K2-14, Research Triangle Park, NC 
27709; telephone: (919) 316-4637; FAX: (301) 480-2970; 
[email protected].

FOR FURTHER INFORMATION CONTACT: Questions or comments concerning the 
14th RoC should be directed to Dr. Lunn (see ADDRESSES).

SUPPLEMENTARY INFORMATION: 

Background Information on the RoC

    The RoC is a congressionally mandated document that identifies and 
discusses agents, substances, mixtures, or exposure circumstances 
(collectively referred to as ``substances'') that may pose a hazard to 
human health because of their carcinogenicity. Substances are listed in 
the report as either known or reasonably anticipated to be human 
carcinogens. The listing of a substance in the RoC indicates a 
potential hazard, but does not establish the exposure conditions that 
pose a cancer hazard to individuals in their daily lives. For each 
listed substance, the RoC provides information from cancer studies that 
support the listing, as well as information about potential sources of 
exposure and current federal regulations to limit exposures. Each 
edition of the RoC is cumulative, that is, it lists newly reviewed 
substances in addition to substances listed in the previous edition. 
Information about the RoC is available on the RoC Web site (http://ntp.niehs.nih.gov/go/roc) or by contacting Dr. Lunn (see ADDRESSES).
    NTP prepares the RoC on behalf of the Secretary of Health and Human 
Services. For the 14th RoC, NTP followed an established, multi-step 
process with multiple opportunities for public input, and used 
established criteria to evaluate the scientific evidence on each 
candidate substance under review (http://ntp.niehs.nih.gov/go/rocprocess).
    New Listings in the 14th RoC: The 14th RoC contains 248 listings, 
some of which consist of a class of structurally related chemicals or 
agents. There are six new listings and one revised listing in this 
edition. The revised listing is for trichloroethylene, which was 
previously listed as reasonably anticipated to be a human carcinogen 
and is now listed as known to be a human carcinogen. Five of the new 
listings are in the category of known to be a human carcinogen: Epstein 
Bar virus, Kaposi sarcoma-associated herpesvirus, human T-cell 
lymphotropic virus type 1, human immunodeficiency virus-type 1, and 
Merkel cell polyomavirus. The new listing in the category of reasonably 
anticipated to be a human carcinogen is for cobalt and cobalt compounds 
that release cobalt ions in vivo.

    Dated: October 25, 2016.
Linda S. Birnbaum,
Director, National Institute of Environmental Health Science and 
National Toxicology Program.
[FR Doc. 2016-26604 Filed 11-2-16; 8:45 am]
 BILLING CODE 4140-01-P