[Federal Register Volume 81, Number 91 (Wednesday, May 11, 2016)]
[Rules and Regulations]
[Pages 29142-29145]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-11204]
[[Page 29142]]
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DEPARTMENT OF JUSTICE
Drug Enforcement Administration
21 CFR Part 1308
[Docket No. DEA-417]
Schedules of Controlled Substances: Placement of UR-144, XLR11,
and AKB48 into Schedule I
AGENCY: Drug Enforcement Administration, Department of Justice.
ACTION: Final rule.
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SUMMARY: With the issuance of this final rule, the Drug Enforcement
Administration places (1-pentyl-1H-indol-3-yl)(2,2,3,3-
tetramethylcyclopropyl)methanone (UR-144), [1-(5-fluoro-pentyl)-1H-
indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (5-fluoro-UR-144,
XLR11), and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide
(APINACA, AKB48), including their salts, isomers, and salts of isomers
whenever the existence of such salts, isomers, and salts of isomers is
possible, into schedule I of the Controlled Substances Act. This
scheduling action is pursuant to the Controlled Substances Act which
requires that such actions be made on the record after opportunity for
a hearing through formal rulemaking. This action imposes the regulatory
controls and administrative, civil, and criminal sanctions applicable
to schedule I controlled substances on persons who handle (manufacture,
distribute, reverse distribute, import, export, engage in research,
conduct instructional activities or chemical analysis, or possess), or
propose to handle UR-144, XLR11, or AKB48.
DATES: Effective: May 11, 2016.
FOR FURTHER INFORMATION CONTACT: Barbara J. Boockholdt, Office of
Diversion Control, Drug Enforcement Administration; Mailing Address:
8701 Morrissette Drive, Springfield, Virginia 22152; Telephone: (202)
598-6812.
SUPPLEMENTARY INFORMATION:
Legal Authority
The Drug Enforcement Administration (DEA) implements and enforces
titles II and III of the Comprehensive Drug Abuse Prevention and
Control Act of 1970, as amended. 21 U.S.C. 801-971. Titles II and III
are referred to as the ``Controlled Substances Act'' and the
``Controlled Substances Import and Export Act,'' respectively, and are
collectively referred to as the ``Controlled Substances Act'' or the
``CSA'' for the purposes of this action. 21 U.S.C. 801-971. The DEA
publishes the implementing regulations for these statutes in title 21
of the Code of Federal Regulations (CFR), chapter II.
The CSA and its implementing regulations are designed to prevent,
detect, and eliminate the diversion of controlled substances and listed
chemicals into the illicit market while ensuring an adequate supply is
available for the legitimate medical, scientific, research, and
industrial needs of the United States. Controlled substances have the
potential for abuse and dependence and are controlled to protect the
public health and safety.
Under the CSA, each controlled substance is classified into one of
five schedules based upon its potential for abuse, its currently
accepted medical use in treatment in the United States, and the degree
of dependence the substance may cause. 21 U.S.C. 812. The initial
schedules of controlled substances established by Congress are found at
21 U.S.C. 812(c) and the current list of scheduled substances is
published at 21 CFR part 1308. 21 U.S.C. 812(a).
Pursuant to 21 U.S.C. 811(a)(1), the Attorney General may, by rule,
``add to such a schedule or transfer between such schedules any drug or
other substance if he . . . finds that such drug or other substance has
a potential for abuse, and . . . makes with respect to such drug or
other substance the findings prescribed by subsection (b) of section
812 of this title for the schedule in which such drug is to be placed .
. . .'' The Attorney General has delegated scheduling authority under
21 U.S.C. 811 to the Administrator of the DEA, 28 CFR 0.100, who in
turn has redelegated that authority to the Deputy Administrator of the
DEA, 28 CFR part 0, appendix to subpart R.
The CSA provides that proceedings for the issuance, amendment, or
repeal of the scheduling of any drug or other substance may be
initiated by the Attorney General (1) on her own motion; (2) at the
request of the Secretary of the Department of Health and Human Services
(HHS); \1\ or (3) on the petition of any interested party. 21 U.S.C.
811(a). This action was initiated by the former DEA Administrator on
her own motion and is supported by a recommendation from the Assistant
Secretary of the HHS and an evaluation of all other relevant data by
the DEA. This action imposes the regulatory controls and
administrative, civil, and criminal sanctions of schedule I controlled
substances on any person who handles, or proposes to handle, UR-144,
XLR11, or AKB48.
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\1\ As set forth in a memorandum of understanding entered into
by the Food and Drug Administration (FDA) and the National Institute
on Drug Abuse (NIDA), the FDA acts as the lead agency within the HHS
in carrying out the Secretary's scheduling responsibilities under
the CSA, with the concurrence of NIDA. 50 FR 9518, Mar. 8, 1985. The
Secretary of the HHS has delegated to the Assistant Secretary for
Health of the HHS the authority to make domestic drug scheduling
recommendations. 58 FR 35460, July 1, 1993. Accordingly, all
subsequent references to ``Secretary'' have been replaced with
``Assistant Secretary.''
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Background
On April 12, 2013, the DEA published a notice of intent to
temporarily place (1-pentyl-1H-indol-3-yl)(2,2,3,3-
tetramethylcyclopropyl)methanone (UR-144), [1-(5-fluoro-pentyl)-1H-
indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (5-fluoro-UR-144,
XLR11), and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide
(APINACA, AKB48) into schedule I pursuant to the temporary scheduling
provisions of the CSA. 78 FR 21858. On May 16, 2013, the DEA published
a final order amending 21 CFR 1308.11(h) to temporarily place these
three synthetic cannabinoids into schedule I of the CSA pursuant to the
temporary scheduling provisions of 21 U.S.C. 811(h). 78 FR 28735. That
final order was effective on the date of publication, and was based on
findings by the DEA that the temporary scheduling of these three
synthetic cannabinoids was necessary to avoid an imminent hazard to the
public safety pursuant to 21 U.S.C. 811(h)(1). Section 201(h)(2) of the
CSA requires that the temporary control of these substances expire two
years from the effective date of the scheduling order, or on May 15,
2015. 21 U.S.C. 811(h)(2). However, the CSA also provides that the
temporary scheduling may be extended for up to one year during the
pendency of proceedings under 21 U.S.C. 811(a)(1). Id. Accordingly, on
May 14, 2015, the DEA published a notice of proposed rulemaking (NPRM)
to permanently control UR-144, XLR11, and AKB48 in schedule I of the
CSA. 80 FR 27611. Specifically, the DEA proposed to add these
substances to 21 CFR 1308.11(g), cannabimimetic agents. On May 15,
2015, the DEA extended the temporary scheduling of UR-144, XLR11, and
AKB48 by one year, until May 15, 2016. 80 FR 27854. On March 22, 2016,
the DEA published a corrected notice of proposed rulemaking, proposing
the placement of these substances as hallucinogenic substances under 21
CFR 1308.11(d), and providing an opportunity to comment on this
proposed change. 81 FR 15188.
[[Page 29143]]
DEA and HHS Eight Factor Analyses
On May 11, 2015, the HHS provided the DEA with three scientific and
medical evaluation documents prepared by the FDA entitled ``Basis for
the recommendation to place 1-pentyl-1H-indol-3-yl-2,2,3,3-
tetramethylcyclopropyl methanone (UR-144) and its salts in Schedule 1
of the Controlled Substances Act (CSA);'' ``Basis for the
recommendation to place 1-(5-fluoro-pentyl)-1H-indol-3-yl 2,2,3,3-
tetramethylcyclopropyl methanone (XLR11) and its salts in Schedule 1 of
the Controlled Substances Act (CSA);'' and ``Basis for the
recommendation to place (N-(1-adamantyl)-1-pentyl-1H-indazole-3-
carboxamide) (AKB48; APINACA) and its salts in Schedule 1 of the
Controlled Substances Act (CSA).'' After considering the eight factors
in 21 U.S.C. 811(c), including consideration of each substance's abuse
potential, legitimate medical use, and dependence liability, the
Assistant Secretary of the HHS recommended that UR-144, XLR11, and
AKB48 be controlled in schedule I of the CSA. In response, the DEA
conducted its own eightfactor analysis of UR-144, XLR11, and AKB48. The
DEA and HHS analyses are available in their entirety in the public
docket for this rule (DEA-2015-0007/agency Docket Number DEA-417) at
http://www.regulations.gov under ``Supporting Documents.''
Determination To Schedule UR-144, XLR11, and AKB48
After a review of the available data, including the scientific and
medical evaluations and the scheduling recommendations from the HHS,
the DEA published an NPRM entitled ``Schedules of Controlled
Substances: Placement of UR-144, XLR11, and AKB48 into Schedule I,''
proposing to control UR-144, XLR11, and AKB48 in schedule I of the CSA.
80 FR 27611, May 14, 2015. The proposed rule provided an opportunity
for interested persons to file a request for hearing in accordance with
the DEA regulations on or before June 15, 2015. No requests for such a
hearing were received by the DEA. The NPRM also provided an opportunity
for interested persons to submit written comments on the proposal on or
before June 15, 2015.
Comments Received
The DEA received three comments on the proposed rule to control UR-
144, XLR11, and AKB48 in schedule I of the CSA. One commenter stated
that the ``longwinded and unnecessarily difficult names of the chemical
substances mentioned'' were offensive and that they should be changed
``in the name of a truly transparent government.'' A second commenter
questioned the safety of methadone, and the third commenter opposed the
control of UR-144, XLR11, and AKB48.
Two comments were received in response to the publication of the
NPRM correction, for which comments were to be limited to addressing
the change in the proposed placement in the CFR for the substances as
hallucinogenic substances rather than cannabimimetic agents Both
comments addressed whether or not these substances should be scheduled,
with one commenter supporting scheduling and the other opposing. Thus,
both comments were outside the scope for which comments were being
accepted.
Comments Received in Response to NPRM.
Request to Shorten Chemical Names. One commenter stated that the
chemical names for UR-144, XLR11, and AKB48 were unnecessarily
difficult to understand and requested they be shortened.
DEA Response: In order to ensure the public is aware of the
specific substances that were proposed to be controlled, and are
controlled, as schedule I substances, the DEA used both the standard
chemical names for UR-144, XLR11, and AKB48 and the common street level
names that correspond to each substance. All names known by the DEA for
UR-144, XLR11, and AKB48 were provided in the NPRM, the NPRM
correction, and in this final rule. In addition, to prevent any
confusion with nomenclature or other references to these substances,
the DEA also used shortened names for these substances, including UR-
144, XLR11, 5-fluoro-UR-144, AKB48, and APINACA. Each of the names
provided in the NPRM, the NPRM correction, and this final rule are
commonly accepted identifiers for the three substances.
Comment Regarding Methadone. One commenter stated that methadone is
very dangerous to use, especially with the consumption of alcohol.
DEA Response: Methadone is a schedule II synthetic opioid and is
not affected by this rule.
Request Not to Control UR-144, XLR11, and AKB48. One commenter
opposed controlling UR-144, XLR11, and AKB48 stating ``there is no
reason to have this law.''
DEA Response: As outlined in detail in the HHS and DEA eight-factor
analyses, there is substantial evidence to support control of UR-144,
XLR11, and AKB48 in schedule I of the CSA.
The use of UR-144, XLR11, and/or AKB48 has been linked to serious
adverse effects including vomiting, nausea, anxiety, agitation,
seizures, hallucinations, tachycardia, and stroke, which require visits
to emergency facilities. In addition to the serious adverse effects,
the misuse and abuse of UR-144, XLR11, and/or AKB48 has been shown to
result in death. As reported by the National Forensic Laboratory
Information System (NFLIS), there have been over 46,000 reports for UR-
144, XLR11, and AKB48 since 2011 in at least 44 states. As determined
by the HHS, there is no accepted medical use for UR-144, XLR11, and
AKB48.
Scheduling Conclusion
After consideration of the relevant matter presented as a result of
public comment, the scientific and medical evaluations and accompanying
recommendations of the HHS, and its own eight-factor analyses, the DEA
finds that these facts and all other relevant data constitute
substantial evidence of potential for abuse of UR-144, XLR11, and
AKB48. As such, the DEA is permanently scheduling UR-144, XLR11, and
AKB48 as controlled substances under the CSA.\2\
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\2\ UR-144, XLR11, and AKB48 were initially proposed to be
scheduled under Sec. 1308.11(g). However, they do not meet the
structural requirement for ``cannabimimetic agents.'' Consistent
with the analysis set forth in the DEA's 8-factor analysis, on March
22, 2016, the DEA published a corrected notice of proposed
rulemaking, with opportunity for comment, proposing the placement of
these substances as hallucinogenic substances under 21 CFR
1308.11(d). 81 FR 15188. The substances are being placed under Sec.
1308.11(d), hallucinogenic substances, under this final rule.
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Determination of Appropriate Schedule
The CSA establishes five schedules of controlled substances known
as schedules I, II, III, IV, and V. The CSA also outlines the findings
required to place a drug or other substance in any particular schedule.
21 U.S.C. 812(b). After consideration of the analyses and
recommendations of the Assistant Secretary for HHS and review of all
other available data, the Administrator of the DEA, pursuant to 21
U.S.C. 811(a) and 21 U.S.C. 812(b)(1), finds that:
(1) (1-pentyl-1H-indol-3-yl)(2,2,3,3-
tetramethylcyclopropyl)methanone (UR-144), [1-(5-fluoro-pentyl)-1H-
indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (5-fluoro-UR-144,
XLR11), and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide
(APINACA, AKB48) have a high potential for abuse that is comparable to
other schedule I substances such as delta-9-
[[Page 29144]]
tetrahydrocannabinol ([Delta]\9\-THC) and JWH-018;
(2) (1-pentyl-1H-indol-3-yl)(2,2,3,3-
tetramethylcyclopropyl)methanone (UR-144), [1-(5-fluoro-pentyl)-1H-
indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (5-fluoro-UR-144,
XLR11), and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide
(APINACA, AKB48) have no currently accepted medical use in treatment in
the United States; and
(3) There is a lack of accepted safety for use of (1-pentyl-1H-
indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (UR-144), [1-(5-
fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone
(5-fluoro-UR-144, XLR11) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-
carboxamide (APINACA, AKB48) under medical supervision.
Based on these findings, the Administrator of the DEA concludes
that (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
(UR-144), [1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-
tetramethylcyclopropyl)methanone (5-fluoro-UR-144, XLR11), and N-(1-
adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA, AKB48)
including their salts, isomers and salts of isomers, whenever the
existence of such salts, isomers, and salts of isomers is possible,
warrant control in schedule I of the CSA. 21 U.S.C. 812(b)(1).
Requirements for Handling UR-144, XLR11, and AKB48
UR-144, XLR11, and AKB48 are currently scheduled on a temporary
basis in schedule I \3\ and therefore continue to be subject to the
regulatory controls and administrative, civil, and criminal sanctions
applicable to the manufacture, distribution, reverse distribution,
importation, exportation, engagement in research and conduct of
instructional activities or chemical analysis, and possession of
schedule I controlled substances, including those listed below. These
controls will continue on a permanent basis:
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\3\ UR-144, XLR11, and AKB48 are currently subject to schedule I
controls on a temporary basis, pursuant to 21 U.S.C. 811(h). 80 FR
27854, May 15, 2016.
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1. Registration. Any person who handles (manufactures, distributes,
reverse distributes, imports, exports, engages in research, or conducts
instructional activities or chemical analysis with, or possesses) UR-
144, XLR11, or AKB48, or who desires to handle UR-144, XLR11, or AKB48
must be registered with the DEA to conduct such activities pursuant to
21 U.S.C. 822, 823, 957, and 958, and in accordance with 21 CFR parts
1301 and 1312.
2. Disposal of Stocks. UR-144, XLR11, and AKB 48 must be disposed
of in accordance with 21 CFR part 1317, in addition to all other
applicable federal, state, local, and tribal laws.
3. Security. UR-144, XLR11, and AKB48 continue to be subject to
schedule I security requirements and must be handled and stored
pursuant to 21 U.S.C. 821, 823, and 871(b), and in accordance with 21
CFR 1301.71-1301.93.
4. Labeling and Packaging. All labels, labeling, and packaging for
commercial containers of UR-144, XLR11, and AKB48 must comply with 21
U.S.C. 825 and 958(e), and be in accordance with 21 CFR part 1302.
5. Quota. Only registered manufacturers are permitted to
manufacture UR-144, XLR11, or AKB48 in accordance with a quota assigned
pursuant to 21 U.S.C. 826 and in accordance with 21 CFR part 1303.
6. Inventory. Every DEA registrant required to keep records and who
possesses any quantity of UR-144, XLR11, or AKB48 is required to
maintain an inventory of all stocks of UR-144, XLR11, and/or AKB48 on
hand, pursuant to 21 U.S.C. 827 and 958, and in accordance with 21 CFR
1304.03, 1304.04, and 1304.11.
7. Records and Reports. Every DEA registrant must maintain records
and submit reports pursuant to 21 U.S.C. 827 and 958, and in accordance
with 21 CFR parts 1304, 1312, and 1317. Manufacturers and distributors
must submit reports regarding UR-144, XLR11, and/or AKB48 to the
Automation of Reports and Consolidated Order System (ARCOS) pursuant to
21 U.S.C. 827 and in accordance with 21 CFR 1304 and 1312.
8. Order Forms. Every DEA registrant who distributes UR-144, XLR11,
and/or AKB48 must continue to comply with the order form requirements,
pursuant to 21 U.S.C. 828 and 21 CFR part 1305.
9. Importation and Exportation. All importation and exportation of
UR-144, XLR11, and AKB48 must be in compliance with 21 U.S.C. 952, 953,
957, and 958, and in accordance with 21 CFR part 1312.
10. Liability. Any activity involving UR-144, XLR11, or AKB48 not
authorized by, or in violation of, the CSA or its implementing
regulations continues to be unlawful, and may subject the person to
administrative, civil, and/or criminal sanctions.
Regulatory Analyses
Administrative Procedure Act
The Administrative Procedure Act (APA) generally requires that
rules enacted in accordance with the procedures of 5 U.S.C. 553 to be
effective not less than 30 days after publication of the proposed rule.
5 U.S.C. 553(d). However, the APA provides three exceptions for when an
agency may make a rule effective sooner than 30 days after publication,
including if the agency finds for good cause why the rule should be
effective sooner and publishes those reasons with the rule. 5 U.S.C.
553(d)(3). The DEA finds that there is good cause for this scheduling
action to be immediately effective upon publication. A delay in the
effective date is unnecessary and contrary to the public interest. It
is unnecessary because UR-144, XLR11, and AKB48 are already controlled
under 21 U.S.C. 811(h). Additionally, a delay in the effective date
could potentially temporarily eliminate these substances from being
controlled, thereby resulting in an imminent hazard to the public
safety. As noted above, the use of UR-144, XLR11, and/or AKB48 has been
linked to serious adverse effects including vomiting, nausea, anxiety,
agitation, seizures, hallucinations, tachycardia, and stroke, which
require visits to emergency facilities. In addition to the serious
adverse effects, the misuse and abuse of UR-144, XLR11, and/or AKB48
has been shown to result in death.
Executive Orders 12866 and 13563, Regulatory Planning and Review, and
13563, Improving Regulation and Regulatory Review
In accordance with 21 U.S.C. 811(a), this scheduling action is
subject to formal rulemaking procedures done ``on the record after
opportunity for a hearing,'' which are conducted pursuant to the
provisions of 5 U.S.C. 556 and 557. The CSA sets forth the criteria for
scheduling a drug or other substance. Such actions are exempt from
review by the Office of Management and Budget (OMB) pursuant to section
3(d)(1) of Executive Order 12866 and the principles reaffirmed in
Executive Order 13563.
Executive Order 12988, Civil Justice Reform
This regulation meets the applicable standards set forth in
sections 3(a) and 3(b)(2) of Executive Order 12988 to eliminate
drafting errors and ambiguity, minimize litigation, provide a clear
legal standard for affected conduct, and
[[Page 29145]]
promote simplification and burden reduction.
Executive Order 13132, Federalism
This rulemaking does not have federalism implications warranting
the application of Executive Order 13132. The proposed rule does not
have substantial direct effects on the States, on the relationship
between the national government and the States, or the distribution of
power and responsibilities among the various levels of government.
Executive Order 13175, Consultation and Coordination With Indian Tribal
Governments
This rule does not have tribal implications warranting the
application of Executive Order 13175. It does not have substantial
direct effects on one or more Indian tribes, on the relationship
between the Federal Government and Indian tribes, or on the
distribution of power and responsibilities between the Federal
Government and Indian tribes.
Regulatory Flexibility Act
The Administrator, in accordance with the Regulatory Flexibility
Act (RFA), 5 U.S.C. 601-602, has reviewed this final rule and by
approving it certifies that it will not have a significant economic
impact on a substantial number of small entities. On May 16, 2013, the
DEA published a final order amending 21 CFR 1308.11(h) to temporarily
place these three synthetic cannabinoids into schedule I of the CSA
pursuant to the temporary scheduling provisions of 21 U.S.C. 811(h). 78
FR 28735. On May 15, 2015, the DEA published a final order extending
the temporary placement of these substances in schedule I of the CSA
for up to one year pursuant to 21 U.S.C. 811(h)(2). 80 FR 27854.
Accordingly, all entities that currently handle or plan to handle these
synthetic cannabinoids are estimated to have already established and
implemented the systems and processes required to handle UR-144, XLR11,
and AKB48. Therefore, the DEA anticipates that this rule will impose
minimal or no economic impact on businesses that currently handle UR-
144, XLR11, or AKB48 for lawful purposes. This estimate applies to
entities large and small. Accordingly, the DEA has concluded that this
rule will not have a significant effect on a substantial number of
small entities.
Unfunded Mandates Reform Act of 1995
On the basis of information contained in the ``Regulatory
Flexibility Act'' section above, the DEA has determined and certifies
pursuant to the Unfunded Mandates Reform Act (UMRA) of 1995, 2 U.S.C.
1501 et seq., that this action will not result in any Federal mandate
that may result in the expenditure by State, local, and tribal
governments, in the aggregate, or by the private sector, of
$100,000,000 or more (adjusted for inflation) in any one year.
Therefore, neither a Small Government Agency Plan nor any other action
is required under provisions of the UMRA of 1995.
Paperwork Reduction Act of 1995
This action does not impose a new collection of information under
the Paperwork Reduction Act of 1995. 44 U.S.C. 3501-3521. This action
would not impose recordkeeping or reporting requirements on State or
local governments, individuals, businesses, or organizations. An agency
may not conduct or sponsor, and a person is not required to respond to,
a collection of information unless it displays a currently valid OMB
control number.
Congressional Review Act
This rule is not a major rule as defined by section 804 of the
Small Business Regulatory Enforcement Fairness Act of 1996
(Congressional Review Act (CRA)). This rule will not result in: ``an
annual effect on the economy of $100,000,000 or more; a major increase
in costs or prices for consumers, individual industries, Federal,
State, or local government agencies, or geographic regions; or
significant adverse effects on competition, employment, investment,
productivity, innovation, or on the ability of U.S.-based companies to
compete with foreign based companies in domestic and export markets.''
However, pursuant to the CRA, the DEA has submitted a copy of this
final rule to both Houses of Congress and to the Comptroller General.
List of Subjects in 21 CFR Part 1308
Administrative practice and procedure, Drug traffic control,
Reporting and recordkeeping requirements.
For the reasons set out above, 21 CFR part 1308 is amended as
follows:
PART 1308--SCHEDULES OF CONTROLLED SUBSTANCES
0
1. The authority citation for 21 CFR part 1308 continues to read as
follows:
Authority: 21 U.S.C. 811, 812, 871(b), unless otherwise noted.
0
2. In Sec. 1308.11:
0
a. Add paragraphs (d) (48) through (50); and
0
b. Remove paragraphs (h)(1) through (3) and redesignate paragraphs
(h)(4) through (25) as paragraphs (h)(1) through (22), respectively.
The additions read as follows:
Sec. 1308.11 Schedule I.
* * * * *
(d) * * *
(48) (1-pentyl-1H-indol-3-yl)(2,2,3,3- (7144)
tetramethylcyclopropyl)methanone (UR-144)...................
(49) [1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3- (7011)
tetramethylcyclopropyl)methanone (5-fluoro-UR-144, XLR11)...
(50) N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (7048)
(APINACA, AKB48)............................................
* * * * *
Dated: May 6, 2016.
Chuck Rosenberg,
Acting Administrator.
[FR Doc. 2016-11204 Filed 5-10-16; 8:45 am]
BILLING CODE 4410-09-P