[Federal Register Volume 79, Number 70 (Friday, April 11, 2014)]
[Notices]
[Page 20209]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2014-08141]



[[Page 20209]]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention (CDC)

[CDC-2014-0006, Docket Number NIOSH-273]


Notice of Draft Document for Public Comment

AGENCY: National Institute for Occupational Safety and Health (NIOSH) 
of the Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (HHS).

ACTION: Notice of draft document for public comment.

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SUMMARY: The National Institute for Occupational Safety and Health of 
the Centers for Disease Control and Prevention announces the 
availability of a draft method to be published in the NIOSH Manual of 
Analytical Methods (NMAM) entitled ``Method 8324: 3-Bromopropionic acid 
in urine; A metabolite of 1-bromopropane'' now available for public 
comment. To view the notice and related materials, visit http://www.regulations.gov and enter CDC-2014-0006 in the search field and 
click ``Search.''
    Public comment period: Comments must be received June 10, 2014.

ADDRESSES: You may submit comments, identified by CDC-2014-0006 and 
Docket Number NIOSH-273, by either of the following two methods:
     Federal eRulemaking Portal: https://www.regulations.gov 
Follow the instructions for submitting comments.
     Mail: NIOSH Docket Office, Robert A. Taft Laboratories, 
4676 Columbia Parkway, MS C-34, Cincinnati, Ohio 45226.
    Instructions: All information received in response to this notice 
must include the agency name and docket number [CDC-2014-0006; NIOSH-
273]. All relevant comments received will be posted without change 
http://www.regulations.gov, including any personal information 
provided. All information received in response to this notice will also 
be available for public examination and copying at the NIOSH Docket 
Office, 4676 Columbia Parkway, Room 109, Cincinnati, OH 45226.

SUPPLEMENTARY INFORMATION: 
    Background: The NIOSH Manual of Analytical Methods (NMAM) was first 
published in 1974 and currently contains over 300 methods that can be 
used by the occupational safety and health community to measure worker 
exposures. 1-Bromopropane is an industrial solvent often used as a 
substitute for a number of chlorofluorocarbon solvents which were 
withdrawn from use because of their possible damaging effects to the 
ozone layer. 3-Bromopropionic acid is a human metabolite of 1-
bromopropane and a proposed biomarker of exposure. An accurate and 
precise method was developed for the detection and quantitation of 3-
bromopropionic acid in human urine. This method was published in the 
literature (B'Hymer CB, Cheever KL [2004]. J Chromatogr B 802:361-366). 
The method was validated by a second laboratory and is proposed for 
inclusion in NMAM's 5th Edition.

FOR FURTHER INFORMATION CONTACT: Dale Shoemaker, Ph.D., NIOSH DART, 
4676 Columbia Parkway MS R-7, Cincinnati, OH 45226. (513) 841-4523.

    Dated: April 7, 2014.
John Howard,
Director, National Institute for Occupational Safety and Health, 
Centers for Disease Control and Prevention.
[FR Doc. 2014-08141 Filed 4-10-14; 8:45 am]
BILLING CODE 4163-19-P