[Federal Register Volume 79, Number 25 (Thursday, February 6, 2014)]
[Notices]
[Pages 7218-7219]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2014-02455]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Report on Carcinogens Webinar on Trichloroethylene; Notice of 
Public Webinar and Registration Information

SUMMARY: The National Toxicology Program (NTP) announces a public 
webinar, ``Human Cancer Studies on Exposure to Trichloroethylene (TCE): 
Methods Used To Assess Exposure and Cancer Outcomes.'' The Office of 
the Report on Carcinogens (ORoC), Division of the NTP (DNTP), National 
Institute of Environmental Health Sciences (NIEHS) will hold the 
webinar using Adobe[supreg] Connect\TM\, and the public can register to 
attend.

DATES: 
    Webinar: March 17, 2014, 9:00 a.m. to approximately 1:00 p.m. 
Eastern Daylight Time (EDT).
    Registration for Webinar: February 6, 2014 through March 13, 2014.
    Availability of Webinar Materials: March 3, 2014.

ADDRESSES: Webinar Web page: http://ntp.niehs.nih.gov/go/tcewebinar.

FOR FURTHER INFORMATION CONTACT: Dr. Ruth M. Lunn, Director, ORoC, 
DNTP, NIEHS, P.O. Box 12233, MD K2-14, Research Triangle Park, NC 
27709. Phone: (919) 316-4637; Fax: (301) 480-2970, Email: 
[email protected]. Hand Delivery/Courier: 530 Davis Drive, Room 2138, 
Morrisville, NC 27560.

SUPPLEMENTARY INFORMATION: 
    Background: The Report on Carcinogens (RoC) is a congressionally 
mandated, science-based, public health report that identifies agents, 
substances, mixtures, or exposures (collectively called ``substances'') 
in our environment that are cancer hazards for people living in the 
United States. The NTP prepares the RoC on behalf of the Secretary of 
Health and Human Services following an established, four-part process 
(http://ntp.niehs.nih.gov/go/rocprocess) and using established criteria 
(http://ntp.niehs.nih.gov/go/15209).
    Trichloroethylene (TCE) is a chlorinated alkene used primarily as a 
metal degreaser and is currently listed as reasonably anticipated to be 
a human carcinogen in the RoC. The NTP selected TCE for re-review for 
possible change in listing status in the RoC following solicitation of 
public comment and review by the NTP Board of Scientific Counselors on 
June 21-22, 2012 (http://ntp.niehs.nih.gov/go/9741) (for more 
information on the status of the NTP review of TCE see http://ntp.niehs.nih.gov/go/37899).
    The purpose of this webinar is (1) to obtain external scientific 
input, focusing on issues related to the assessment of information 
(exposure and cancer outcomes) in epidemiologic studies of TCE, which 
will be used to inform the NTP's evaluation of the level of evidence 
from human cancer studies of TCE exposure, and (2) to obtain public 
input on the protocol for preparation of the draft RoC monograph on 
TCE. The first part of the webinar will consist of three presentations, 
with a short question-and-answer period after each presentation, 
followed by a general discussion session on scientific issues across 
all presentations. The goals of the individual presentations are (1) to 
address the adequacy of methods used in the epidemiologic studies to 
assess exposure and cancer outcomes (primarily lymphohematopoietic 
cancers), (2) to discuss and compare reported or estimated exposure 
levels or exposure prevalence across studies, (3) to discuss how this 
information (e.g., data from TCE exposure assessments, quality of 
exposure assessment, TCE exposure levels or prevalence, classification 
of non-Hodgkin lymphoma) is used in the epidemiologic studies and can 
be used to inform the cancer evaluation across studies. The second part 
of the webinar will be a discussion session when the public can either 
make comments on or ask questions about the proposed protocol for 
preparation of the draft RoC monograph on TCE (http://ntp.niehs.nih.gov/NTP/roc/thirteenth/Protocols/TCE_Protocol12-31-13_508.pdf).
    Webinar and Registration: The webinar is scheduled for March 17, 
2014, from 9:00 a.m. to approximately 1 p.m. EDT. The webinar may end 
early if the presentations and discussions are finished. Registration 
for the webinar is required and is open from February 6, 2014 through 
March 13, 2014, at http://ntp.niehs.nih.gov/go/pcpwebinar.

[[Page 7219]]

Registrants will receive instructions by email on accessing the webinar 
(via Adobe[supreg] Connect\TM\) on or before March 14, 2014.
    The preliminary agenda, list of speakers, and abstracts of the 
presentations should be posted on the NTP Web site (http://ntp.niehs.nih.gov/go/tcewebinar) by March 3, 2014. Registrants are 
encouraged to access the webinar Web page to stay abreast of the most 
current information regarding this event. Any updates will be posted to 
the Web page. The protocol for preparing the draft RoC monograph on TCE 
is available on the RoC Web site for TCE (http://ntp.niehs.nih.gov/go/37899).
    Public Participation: As noted above, the meeting format includes 
time after each presentation and during the two discussion sessions for 
the public to ask questions or make brief remarks. Instructions for 
public access and participation in the meeting via Adobe[supreg] 
Connect\TM\ will be emailed to registered attendees. Individuals with 
disabilities who need accommodation to participate in this event should 
contact Dr. Lunn (see FOR FURTHER INFORMATION CONTACT). TTY users 
should contact the Federal TTY Relay Service at 800-877-8339. Requests 
should be made at least five business days in advance of the event.
    Background Information on the RoC: Published biennially, each 
edition of the RoC is cumulative and consists of substances newly 
reviewed in addition to those listed in previous editions. The 12th 
RoC, the latest edition, was published on June 10, 2011 (available at 
http://ntp.niehs.nih.gov/go/roc12). The 13th RoC is under development.

    Dated: January 31, 2014.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2014-02455 Filed 2-5-14; 8:45 am]
BILLING CODE 4140-01-P