[Federal Register Volume 78, Number 183 (Friday, September 20, 2013)]
[Notices]
[Pages 57868-57869]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2013-22890]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Nominations to the Report on Carcinogens; Request for Information

SUMMARY: National Toxicology Program (NTP) Office of the Report on 
Carcinogens (ORoC) requests information on 20 substances, mixtures, and 
exposure circumstances (collectively referred to as ``substances'') 
nominated for possible review for future editions of the Report on 
Carcinogens (RoC).

DATES: The deadline for receipt of information is October 18, 2013.

ADDRESSES: Information can be submitted electronically on the ORoC 
nomination page (http://ntp.niehs.nih.gov/go/rocnom) or to 
[email protected].

FOR FURTHER INFORMATION CONTACT: Dr. Ruth Lunn, Director, ORoC, DNTP, 
NIEHS, P.O. Box 12233, MD K2-14, Research Triangle Park, NC 27709; 
telephone (919) 316-4637; FAX: (301) 480-2970; [email protected]. 
Courier address: NIEHS, Room 2138, 530 Davis Drive, Morrisville, NC 
27560.

SUPPLEMENTARY INFORMATION:
    Request for Information: The NTP requests information on the 20 
substances listed below that have been nominated for possible review 
for future editions of the RoC (for more information, see http://ntp.niehs.nih.gov/go/rocnom). Specifically, the NTP requests 
information on each substance for the following topics: (1) data on 
current production, use patterns, and human exposure; (2) information 
about published, ongoing, or planned studies related to evaluating 
carcinogenicity; (3) scientific issues important for assessing 
carcinogenicity of the substance; and (4) names of scientists with 
expertise or knowledge about the substance. Please include any 
available bibliographic citations for the information. The NTP will use 
this information for identifying

[[Page 57869]]

nominated substances to propose for formal evaluation for the RoC.

20 Substances Nominated to the RoC*

     Aloe vera whole leaf extract (Aloe barbadensis Miller)
     2-Butoxyethanol (CAS No. 111-76-2)
     Chlorothalonil (2,4,5,6-tetrachloro-isophthalonitrile) 
(CAS No. 1897-45-6)
     Coconut diethanolamide (CAS No. 68603-42-9)
     Cobalt (metal) (CAS No. 7440-48-4)
     Decalin (CAS No. 91-17-8)
     Ginkgo biloba extract
     Goldenseal root powder (Hydrastis canadensis)
     Kava kava extract
     2-Methylimidazole (CAS No. 693-98-1)
     4-Methylimidazole (CAS No. 822-36-6)
     Methyl isobutyl ketone (CAS No. 108-10-1)
     Nickel nanoparticles
     Nitro polycyclic aromatic hydrocarbons (PAH) as a class
     Perfluorooctanoic acids (PFOA) (CAS No. 335-67-1)
     Polyacrylates
     Pulegone (CAS No. 89-82-7)
     Tetralin (CAS No. 119-64-2)
     Tris-(1,3-dichloro-2-propyl) phosphate (chlorinated Tris, 
TDCPP) (CAS No. 13674-87-8)
     Wood smoke
    * Nominations to the RoC may seek to list a new substance in the 
report, reclassify the listing status of a substance already listed, or 
remove a listed substance.
    Information can be submitted electronically on the ORoC nomination 
page (http://ntp.niehs.nih.gov/go/rocnom) or by email to 
[email protected]. If submitting by email, please include the 
submitter's name, affiliation, mailing address, phone, email, and 
sponsoring organization (if any) with the document. Written information 
received in response to this notice will be posted on the NTP Web site, 
and the submitter will be identified by name, affiliation, and/or 
sponsoring organization.
    Responses to this request for information are voluntary. This 
request for information is for planning purposes only and is not a 
solicitation for applications or an obligation on the part of the U.S. 
Government to provide support for any ideas identified in response to 
it. Please note that the U.S. Government will not pay for the 
preparation of any information submitted or for its use. No 
proprietary, classified, confidential, or sensitive information should 
be included in your response.
    Background Information on the RoC: The RoC is a congressionally 
mandated, science-based, public health report that identifies agents, 
substances, mixtures, or exposures (collectively called ``substances'') 
in our environment that pose a cancer hazard for people in the United 
States. The NTP prepares the RoC on behalf of the Secretary of Health 
and Human Services. The NTP follows an established, four-part process 
for preparation of the RoC (http://ntp.niehs.nih.gov/go/rocprocess). 
Published biennially, each edition of the RoC is cumulative and 
consists of substances newly reviewed in addition to those listed in 
previous editions. The 12th RoC, the latest edition, was published on 
June 10, 2011 (available at http://ntp.niehs.nih.gov/go/roc12). The 
13th RoC is under development.

    Dated: September 16, 2013.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2013-22890 Filed 9-19-13; 8:45 am]
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