[Federal Register Volume 78, Number 125 (Friday, June 28, 2013)]
[Notices]
[Pages 38982-38983]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2013-15523]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[Docket No. ATSDR-2013-0001]


Availability of Draft Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (DHHS).

ACTION: Notice of availability, and request for comments.

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SUMMARY: This notice announces the availability of Set 25 Toxicological 
Profiles for review and comment. Comments can include additional 
information or reports on studies about the health effects of Set 25 
substances. Although ATSDR considered key studies for each of these 
substances during the profile development process, this Federal 
Register notice solicits any relevant, additional studies, particularly 
unpublished data. ATSDR will evaluate the quality and relevance of such 
data or studies for possible inclusion in the profile. ATSDR remains 
committed to providing a public comment period for this document as a 
means to best serve public health and our clients. The Set 25 
Toxicological Profile is available online at http://www.atsdr.cdc.gov/toxprofiles/index.asp and www.regulations.gov, docket ATSDR-2013-0001.
    The Comprehensive Environmental Response, Compensation, and 
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments 
and Reauthorization Act of 1986 (SARA), Sec.  104(i)(3), [42 U.S.C. 
9604(i)(3)], directs the ATSDR administrator to prepare toxicological 
profiles of priority hazardous substances and, as necessary, to revise 
and publish each updated toxicological profile.

DATES: To be considered, comments on the draft toxicological profiles 
must be received not later than September 30, 2013. Comments received 
after close of the public comment period will be considered solely at 
the discretion of ATSDR, based upon what is deemed to be in the best 
interest of the general public.

ADDRESSES: You may submit comments, identified by docket number ASTDR-
2013-0001, by any of the following methods:
     Federal eRulemaking Portal: http://www.reguations.gov. 
Follow the instructions for submitting comments.
     Mail: Division of Toxicology and Health and Human 
Sciences, 1600 Clifton Rd. NE., MS F57, Atlanta, GA. 30333.
    Instructions: All submissions received must include the agency name 
and docket number for this notice. All relevant comments will be posted 
without change. Because all public comments regarding ATSDR 
toxicological profiles are available for public inspection, no 
confidential business information or other confidential information 
should be submitted in response to this notice. Refer to the section 
Submission of Nominations (below) for specific information required.

FOR FURTHER INFORMATION CONTACT: Ms. Delores Grant, Division of 
Toxicology and Human Health Sciences, 1600 Clifton Rd. NE., MS F-57, 
Atlanta, GA 30333. Phone: 770-488-3351.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization 
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental 
Response, Compensation, and Liability Act (CERCLA or Superfund) (42 
U.S.C. 9601 et seq.) by establishing certain responsibilities for ATSDR 
and the U.S. Environmental Protection Agency (U.S. EPA) with regard to 
hazardous substances most commonly found at facilities on the CERCLA 
National Priorities List (NPL). As part of these responsibilities, the 
ATSDR administrator must prepare toxicological profiles for substances 
enumerated on the priority list of hazardous substances. This list 
identifies 275 hazardous substances which, according to ATSDR and U.S. 
EPA, pose the most significant potential threat to human health. The 
availability of the revised priority list of 275 hazardous substances 
was announced in the Federal Register on March 6, 2008 (73 FR 12178). 
In addition, ATSDR has the authority to prepare toxicological profiles 
for substances not found at sites on the National Priorities List, in 
an effort to ``. . . establish and maintain inventory of literature, 
research, and studies on the health effects of toxic substances'' under 
CERCLA Section 104(i)(1)(B). This is also to respond to requests for 
consultation under section 104(i)(4), and as otherwise necessary to 
support the site-specific response actions conducted by ATSDR.
    Each profile will include an examination, a summary, and an 
interpretation of available toxicological information and 
epidemiological evaluations. This information and these data identify 
the levels of significant human exposure for the substance and for the 
associated health effects. The profiles must also include a 
determination of whether adequate information on the health effects of 
each substance is available or is in the process of development. If 
adequate information is not available, ATSDR, in cooperation with the 
National Toxicology Program (NTP), is required to ensure the initiation 
of a program of research to determine such health effects.
    All toxicological profiles issued as ``Drafts for Public Comment'' 
represent ATSDR's best efforts to provide important toxicological 
information on priority hazardous substances.
    Set 25 toxicological profiles:

[[Page 38983]]



------------------------------------------------------------------------
                                           Name                 CAS
------------------------------------------------------------------------
1..............................  Hexachlorobenzene              118-74-1
                                  (UPDATE).
2..............................  Endosulfan (UPDATE)....        115-29-7
                                 Endosulfan sulfate.....       1031-07-8
                                 Endosulfan-alpha.......        95-99-98
                                 Endosulfan-beta........      33213-65-9
3..............................  1,1-Dichloroethane              75-34-3
                                  (UPDATE).
4..............................  Dinitrotoluenes (DNT)
                                  (UPDATE).
                                 2,3-DNT................        602-01-7
                                 2,4-DNT................        121-14-2
                                 2,5-DNT................        619-15-8
                                 2,6-DNT................        606-20-2
                                 3,4-DNT................        610-39-9
                                 3,5-DNT................        618-85-9
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    Dated: June 21, 2013.
Sascha Chaney,
 Acting Director, Office of Policy, Planning and Evaluation, National 
Center for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. 2013-15523 Filed 6-27-13; 8:45 am]
BILLING CODE 4163-70-P