[Federal Register Volume 78, Number 77 (Monday, April 22, 2013)]
[Notices]
[Pages 23767-23768]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2013-09363]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30Day-13-12RO]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
(404) 639-7570 or send an email to [email protected]. Send written comments 
to CDC Desk Officer, Office of Management and Budget, Washington, DC 
20503 or by fax to (202) 395-5806. Written comments should be received 
within 30 days of this notice.

Proposed Project

    Anniston Community Health Survey: Follow-up and Dioxin Analyses 
(ACHS-II)--New--Agency for Toxic Substances and Disease Registry 
(ATSDR), Department of Health and Human Services (DHHS).

Background and Brief Description

    In the past, polychlorinated biphenyls (PCBs) were used as coolants 
and lubricants in electrical equipment. They didn't burn easily and 
were good insulators. PCBs are no longer made in the U.S. They were 
banned in 1977 because they persist in the environment. The public and 
the scientific community became concerned about harm to human health 
from persistent exposure to PCBs.
    The City of Anniston, AL, was the site of the former Monsanto 
facility. PCBs were made there from 1929 to 1971. For decades, PCBs 
were released into the local air, soil, and surface water. In 1996, 
residents found out they were exposed. Concerns grew and led to 
litigation. In 2003, a settlement in favor of the residents was reached 
in state and federal courts.
    The Anniston Environmental Health Research Consortium (AEHRC) was 
funded by the Agency for Toxic Substances and Disease Registry (ATSDR). 
The AEHRC conducted the Anniston Community Health Survey (ACHS) from 
2005 to 2007. Serum PCB levels in 766 Anniston adults were found to be 
three to seven times higher than in U.S. adults. Also, higher PCB 
levels were found in Anniston adults who had high blood pressure and 
diabetes.
    ATSDR and National Institutes of Health (NIH) plan to continue the 
work of the first ACHS. These agencies will conduct a follow-up study 
called the

[[Page 23768]]

ACHS-II. Data collection will be managed by the University of Alabama 
at Birmingham (UAB) and the Calhoun County Health Department (CCHD).
    A sample of 500 surviving ACHS cohort members with PCBs 
measurements will be enrolled in the ACHS-II. After informed consent, 
clinical assessments will be done. These will be for blood pressure, 
height, weight, hip, and body girth. A questionnaire will be answered 
by computer-assisted personal interviews (CAPIs). Questions will be 
asked for health, demographic, diet, and lifestyle factors. The self-
reported responses will be compared to laboratory analytes. For these, 
blood samples will be drawn and analyzed.
    The ACHS-II will measure the same serum PCBs as in the first 
Anniston survey. In this way, changes in PCB levels can be studied. The 
ACHS-II will also include serum analytes for dioxins, furans, dioxin-
like PCBs, and chlorinated pesticides. Additional analytes include 
blood measures of polybrominated biphenyls and heavy metals. Clinical 
biomarkers will include measures for thyroid, diabetes, lipids, and 
immune function. This will give a more complete profile of human 
exposures and health in Anniston, AL.
    The ATSDR is requesting a two-year approval for this information 
collection. The total annualized burden is 227 hours.
    There are no costs to respondents other than their time. Each 
respondent will spend about 2 hours in the study.

                                        Estimated Annualized Burden Hours
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                                                                                                      Average
                                                                     Number of       Number of      burden per
          Type of respondents                   Form name           respondents    responses per   response  (in
                                                                                    respondent         hrs)
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Adults who took part in first Anniston  Recruitment Telephone                333               1            2/60
 Community Health Survey.                Script.                             160               1            1/60
                                        Survey for Refusals.....             250               1            1/60
                                        Update Contact
                                         Information Form.
                                        Medications Form........             250               1            3/60
                                        Blood Draw Form.........             250               1            2/60
                                        Questionnaire...........             250               1           45/60
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Ron A. Otten,
Director, Office of Scientific Integrity, Office of the Associate 
Director for Science, Office of the Director, Centers for Disease 
Control and Prevention.
[FR Doc. 2013-09363 Filed 4-19-13; 8:45 am]
BILLING CODE 4163-18-P