[Federal Register Volume 77, Number 179 (Friday, September 14, 2012)]
[Notices]
[Pages 56854-56855]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2012-22740]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Submission for OMB Review; Comment Request: A Multi-Center 
International Hospital-Based Case-Control Study of Lymphoma in Asia 
(AsiaLymph) (NCI)

SUMMARY: Under the provisions of Section 3507(a)(1)(D) of the Paperwork 
Reduction Act of 1995, the National Cancer Institute (NCI), the 
National Institutes of Health (NIH), has submitted to the Office of 
Management and Budget (OMB) a request to review and approve the 
information collection listed below. This proposed information 
collection was previously published in the Federal Register on February 
24, 2012 (77 FR 11136) and allowed 60 days for public comment. There 
was one public comment that was not relevant to the scope, methodology, 
or burden of the study. The program staff submitted a response to the 
public comment. The purpose of this notice is to allow an additional 30 
days for public comment. The National Institutes of Health may not 
conduct or sponsor, and the respondent is not required to respond to, 
an information collection that has been extended, revised, or 
implemented on or after October 1, 1995, unless it displays a currently 
valid OMB control number.
    Proposed Collection: Title: A Multi-Center International Hospital-
Based Case-Control Study of Lymphoma in Asia (AsiaLymph) (NCI) (OMB No. 
0925-0654). Type of Information Collection Request: Extension. Need and 
Use of Information Collection: Incidence rates of certain lymphomas 
have increased in the United States and in many other parts of the 
world. The contribution of environmental, occupational, and genetic 
factors to the cause of lymphoma has generated a series of new findings 
from epidemiological studies conducted in the United States that have 
attempted to explain this increase. This study focuses on collecting 
critically needed information to understand and reduce the cancer 
burden from lymphoid malignancies in the Asian population, the 
incidence of which has risen in recent decades. Specifically, 
environmental exposures to industrial emissions, genetic 
susceptibility, viral exposures, early life exposures, ultraviolet (UV) 
radiation exposures, and other risk factors for lymphoma overall and 
specifically for populations in Asia will be examined. Patients from 19 
participating hospitals will continue to be screened and enrolled. 
There will be a one-time computer-administered interview, and patients 
will also be asked to provide a one-time blood and buccal cell mouth 
wash sample and lymphoma cases will be asked to make available a 
portion of their pathology sample. Frequency of Response: Once. 
Affected Public: Individuals. Type of Respondents: Newly diagnosed 
patients with lymphoma or patients undergoing surgery or other 
treatment for non-cancer related medical issues who live in Taiwan and 
in Hong Kong, Chengdu and Tianjin, China will be enrolled at treating 
hospitals. The annual reporting burden is estimated at 5,302 hours (see 
Table below). There are $77,000 in Capital Costs, Operating Costs, and/
or Maintenance Costs to report.

                                                            Estimates of Annual Burden Hours
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                                                                                                                           Average time
            Category of respondents                        Types of respondents              Number of     Frequency of    per response   Annual  burden
                                                                                            respondents      response     (minutes/hour)       hours
--------------------------------------------------------------------------------------------------------------------------------------------------------
Individuals....................................  Patients to be Screened................           3,100               1            5/60             258
                                                 Patients with Lymphoma.................           1,100               1          105/60           1,925
                                                 Other Patients.........................           1,100               1          105/60           1,925
                                                 Study Pathologists.....................              19              58            5/60              92
                                                 Interviewers...........................              19             116           30/60            1102
                                                                                         ---------------------------------------------------------------
    Total......................................  .......................................  ..............  ..............  ..............           5,302
--------------------------------------------------------------------------------------------------------------------------------------------------------

    Request For Comments: Written comments and/or suggestions from the 
public and affected agencies are invited to address one or more of the 
following points: (1) Whether the proposed collection of information is 
necessary for the proposed performance of the functions of the agency, 
including whether the information may have practical utility; (2) The 
accuracy of the estimate of the burden of the proposed collection of 
information including the validity of the methodology and assumptions 
used; (3) Ways to enhance the quality, utility, and clarity of the 
information to be collected; and (4) Ways to minimize the burden of the 
collection of information on those who are to respond, including the 
use of appropriate automated, electronic, mechanical, or other 
technological collection techniques or other forms of information 
technology.
    Direct Comments to OMB: Written comments and/or suggestions 
regarding the item(s) contained in this notice, especially regarding 
the estimated public burden and associated response time, should be 
directed to the Attention: NIH Desk Officer, Office of Management and 
Budget, at [email protected] or by fax to 202-395-6974. To 
request more information on the proposed project or to obtain a copy of 
the data collection plans, contact Nathaniel Rothman, Senior 
Investigator for the Occupational and Environmental Epidemiology 
Branch, Division of Epidemiology and Genetics, National Cancer 
Institute, 6120 Executive Boulevard, Room 8118, Rockville, MD 20892 or 
call non-toll-free number 301-496-9093 or email your request, including 
your address to: [email protected].
    Comments Due Date: Comments regarding this information collection 
are best assured of having their full effect if received within 30 days 
of the date of this publication.


[[Page 56855]]


    Dated: September 5, 2012.
Vivian Horovitch-Kelley,
NCI Project Clearance Liaison, National Institutes of Health.
[FR Doc. 2012-22740 Filed 9-13-12; 8:45 am]
BILLING CODE 4140-01-P