[Federal Register Volume 77, Number 33 (Friday, February 17, 2012)]
[Notices]
[Pages 9665-9666]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2012-3830]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Submission for OMB Emergency Review; Comment Request: A Multi-
Center International Hospital-Based Case-Control Study of Lymphoma in 
Asia (AsiaLymph) (NCI)

    Summary: In accordance with Section 3507(j) of the Paperwork 
Reduction Act of 1995, the National Cancer Institute (NCI), the 
National Institutes of Health (NIH), has submitted to the Office of 
Management and Budget (OMB) a request for emergency review and 
processing this information collection by March 5, 2012. NCI is 
requesting emergency processing of this information collection, 
pursuant to 5 CFR 1320.13, because NCI cannot reasonably comply with 
the normal clearance procedures which would cause a delay and likely 
prevent or substantially disrupt the collection of information. A delay 
in starting the information collection would hinder the agency in 
accomplishing its mission to the detriment of the public good. Public 
harm could result through the loss of critically needed information to 
understand and reduce the cancer burden from lymphoid malignancies in 
the Asian population. The National Institutes of Health may not conduct 
or sponsor, and the respondent is not required to respond to, an 
information collection that has been extended, revised, or implemented 
on or after October 1, 1995, unless it displays a currently valid OMB 
control number.
    Proposed Collection: Title: A Multi-Center International Hospital-
Based Case-Control Study of Lymphoma in Asia (AsiaLymph) (NCI). Type of 
Information Collection Request: Emergency. Need and Use of Information 
Collection: Incidence rates of certain lymphomas have increased in 
several centers in Asia thereby increasing the cancer burden in these 
populations, but the causes remain unknown. AsiaLymph is a multi-
disciplinary case-control study that will confirm and extend previous 
findings and yield novel insights into the causes of lymphoma in both 
Asia and the West. The major postulated risk factors for evaluation in 
this study are chemical exposures (i.e., organochlorines, 
trichloroethylene, and benzene) and genetic susceptibility. Other 
factors potentially related to lymphoma, such as viral infections, 
ultraviolet radiation exposure, medical conditions, and other lifestyle 
factors will also be studied. Patterns of key risk factors, including 
range of exposures, prevalence of exposures, correlations between 
exposures, and variation in gene regions are of particular interest. 
Patients from 19 participating hospitals will be screened and enrolled. 
There will be a one-time computer-administered interview, and patients 
will also be asked to provide a one-time blood and buccal cell mouth 
wash sample and lymphoma cases will be asked to make available a 
portion of their pathology sample. Frequency of Response: Once. 
Affected Public: Individuals. Type of Respondents: Newly diagnosed 
patients with lymphoma or patients undergoing surgery or other 
treatment for non-cancer related medical issues who live in Hong Kong, 
Taiwan, and Chengdu and Tianjin, China will be enrolled at treating 
hospitals. The annual reporting burden is estimated at 3,377 hours (see 
Table below). There are no Capital Costs, Operating Costs, and/or 
Maintenance Costs to report.

                                        Estimates of Annual Burden Hours
----------------------------------------------------------------------------------------------------------------
                                                                                   Average time
 Category of  respondents   Types of respondents     Number of     Frequency of    per response    Annual burden
                                                    respondents      response         (Hours)          hours
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Individuals...............  Patients to be                 3,100               1            5/60             258
                             Screened.
                            Patients with                  1,100               1          105/60             963
                             Lymphoma.
                            Other Patients......           1,100               1          105/60             963
                            Study Pathologists..              19              58            5/60              92
                            Interviewers........              19             116           30/60            1102
                           -------------------------------------------------------------------------------------
    Total.................  ....................  ..............  ..............  ..............           3,377
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    Request for Comments: Written comments and/or suggestions from the 
public and affected agencies should address one or more of the 
following points: (1) Evaluate whether the proposed collection of 
information is

[[Page 9666]]

necessary for the proper performance of the function of the agency, 
including whether the information will have practical utility; (2) 
evaluate the accuracy of the agency's estimate of the burden of the 
proposed collection of information, including the validity of the 
methodology and assumptions used; (3) enhance the quality, utility, and 
clarity of the information to be collected; and (4) minimize the burden 
of the collection of information on those who are to respond, including 
the use of appropriate automated, electronic, mechanical, or other 
technological collection techniques or other forms of information 
technology.
    Direct Comments to OMB: Written comments and/or suggestions 
regarding the item(s) contained in this notice, especially regarding 
the estimated public burden and associated response time, should be 
directed to the Attention: NIH Desk Officer, Office of Management and 
Budget, at [email protected] or by fax to 202-395-6974. To 
request more information on the proposed project or to obtain a copy of 
the data collection plans and instruments, contact Nathaniel Rothman, 
Senior Investigator for the Occupational and Environmental Epidemiology 
Branch, Division of Epidemiology and Genetics, National Cancer 
Institute, 6120 Executive Boulevard, Room 8118, Rockville, MD 20892 or 
call non-toll-free number 301-496-9093 or email your request, including 
your address to: rothmann @mail.nih.gov.
    Comments Due Date: Comments regarding this information collection 
are best assured of having their full effect if received within 15 days 
of the date of this publication.

    Dated: February 13, 2012.
Vivian Horovitch-Kelley,
NCI Project Clearance Liaison, National Institutes of Health.
[FR Doc. 2012-3830 Filed 2-16-12; 8:45 am]
BILLING CODE 4140-01-P