[Federal Register Volume 76, Number 225 (Tuesday, November 22, 2011)]
[Notices]
[Pages 72207-72208]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2011-30109]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, Public Health Service, HHS.

ACTION: Notice.

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SUMMARY: The inventions listed below are owned by an agency of the U.S. 
Government and are available for licensing in the U.S. in accordance 
with 35 U.S.C. 207 to achieve expeditious commercialization of results 
of federally-funded research and development. Foreign patent 
applications are filed on selected inventions to extend market coverage 
for companies and may also be available for licensing.

ADDRESSES: Licensing information and copies of the U.S. patent 
applications listed below may be obtained by writing to the indicated 
licensing contact at the Office of Technology Transfer, National 
Institutes of Health, 6011 Executive Boulevard, Suite 325, Rockville, 
Maryland 20852-3804; telephone: (301) 496-7057; fax: (301) 402-0220. A 
signed Confidential Disclosure Agreement will be required to receive 
copies of the patent applications.

Medical Device for Intraocular Injection of Therapeutics and Fluid 
Sampling

    Description of Technology: The National Institutes of Health seeks 
research collaboration and commercialization partners for a medical 
device for administering therapeutics into the eye to treat a variety 
of ocular diseases including diabetic retinopathy, retinal vein 
occlusion, and macular degeneration. The device is a dual function 
needle that can both inject and sample ocular fluid at the same 
injection site. The needle includes a hub portion in communication with 
a needle portion through a lumen that may be used as a conduit to 
inject a therapeutic into an injection site. A sample chamber, with an 
optional absorbent material, is

[[Page 72208]]

disposed in the lumen capable of absorbing intraocular fluid via a 
passive filling action into the sample chamber.
    Potential Commercial Applications:
     Ocular therapeutics
     Macular degeneration
     Diabetic retinopathy
     Retinal vein occlusion
    Competitive Advantages:
     Small sample volumes
     Disposable
     Personalized medicine
    Development Stage:
     Prototype
     Early-stage
    Inventors: Henry E. Wiley (NEI), Terrence M. Philips (NIBIB), 
Fredrick L. Ferris (NEI), Heather Kalish (NIBIB).
    Intellectual Property: HHS Reference No. E-233-2010/0--U.S. 
Provisional Patent Application No. 61/533,908 filed September 13, 2011.
    Licensing Contact: Michael Shmilovich, Esq.; (301) 435-5019; 
[email protected].
    Collaborative Research Opportunity: The National Eye Institute is 
seeking statements of capability or interest from parties interested in 
collaborative research to further develop, evaluate or commercialize 
intraocular therapeutic delivery. For collaboration opportunities, 
please contact Alan E. Hubbs, Ph.D. at (301) 594-4263 or 
[email protected].

Bacteria/Biofilm Resistant Implantable Medical Device

    Description of Technology: Available for licensing and commercial 
development is a medical device resistant to a biological barrier such 
as a bacterial biofilm, fibrin sheath, and/or clot formation. An 
electric current is introduced through an electrically conductive 
surface of the device (e.g., a catheter) on which a biofilm, fibrin 
sheath, or clot may form to inhibit formation. The electrically 
conductive surface can extend along an entire surface of the device 
(for example extending entirely from the proximal to distal end of a 
catheter), or a portion thereof such as at the tip.
    Potential Commercial Applications:
     Biofilm resistant medical devices
     Antimicrobial methods
     Antimicrobial protection of implanted medical device
     Vascular access devices
    Competitive Advantages: Non-degradable antimicrobial methods.
    Development Stage:
     Prototype
     Early-stage
    Inventors: Bradford Wood and Ziv Neeman (NIHCC).
    Intellectual Property: HHS Reference No. E-078-2005--U.S. 
Provisional Patent Application 61/501,065 filed June 24, 2011.
    Licensing Contact: Michael Shmilovich, Esq.; (301) 435-5019; 
[email protected].

    Dated: November 16, 2011.
Richard U. Rodriguez,
Director, Division of Technology Development and Transfer, Office of 
Technology Transfer, National Institutes of Health.
[FR Doc. 2011-30109 Filed 11-21-11; 8:45 am]
BILLING CODE 4140-01-P