[Federal Register Volume 76, Number 173 (Wednesday, September 7, 2011)]
[Notices]
[Page 55384]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2011-22660]


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ENVIRONMENTAL PROTECTION AGENCY

[EPA/100/J-11/001; FRL-9460-1]


External Peer Review Meeting for the Draft Guidance of Applying 
Quantitative Data To Develop Data-Derived Extrapolation Factors for 
Interspecies and Intraspecies Extrapolation

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice.

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SUMMARY: EPA is announcing that Eastern Research Group, Inc. (ERG), a 
contractor to the EPA, will convene an independent panel of experts to 
review the draft document, ``Guidance for Applying Quantitative Data to 
Develop Data-Derived Extrapolation Factors for Interspecies and 
Intraspecies Extrapolation.'' EPA previously announced the release of 
the draft guidance for a 45 day comment period (76 FR 33752-33753), 
which was subsequently extended to 60 days (76 FR 43999). The public 
comment period ended August 9, 2011. EPA intends to forward public 
comments to the contractor for distribution to members of the review 
panel. The external review draft does not represent Agency policy.
    The public may register to attend this peer review meeting as 
observers. Time will be set aside for observers to give brief oral 
comments at the meeting on the draft document. The draft document and 
appendix are available via the internet on the Risk Assessment Forum 
Web page (http://www.epa.gov/raf/DDEF/index.htm). When finalizing the 
draft document, EPA intends to consider the comments from the external 
peer review meeting along with public comments received by August 9, 
2011 in accordance with 76 FR 33752-33753 and 76 FR 43999. Public 
comments submitted during the public comment period ending August 9, 
2011, may be viewed at http://www.regulations.gov under Docket ID No. 
EPA-HQ-ORD-2009-0694.

DATES: The peer review panel meeting on the draft document, ``Guidance 
for Applying Quantitative Data to Develop Data-Derived Extrapolation 
Factors for Interspecies and Intraspecies Extrapolation'' will be held 
on Monday, September 12, 2011, beginning at 8:30 a.m. and ending at 5 
p.m. Eastern Daylight Time.

ADDRESSES: The meeting will be held at the following location: L'Enfant 
Plaza Hotel, 480 L'Enfant Plaza, SW., Washington, DC 20024.
    Instructions: To attend the peer review meeting as an observer 
register no later than September 5, 2011, call ERG at (781) 674-7374 or 
toll free at (800) 803-2833 (the DDEF peer review coordinator is Laurie 
Waite); or send a facsimile to (781) 674-2906 (reference the ``DDEF 
Peer Review Meeting'' and include your name, title, affiliation, full 
address and contact information), or send an e-mail to [email protected] 
(reference the ``DDEF Peer Review Meeting'' and include your name, 
title, affiliation, full address and contact information). Internet 
registration is available at https://www2.ergweb.com/projects/conferences/peerreview/register-ddef.htm. Space is limited, and 
registrations will be accepted on a first-come, first-served basis. 
There will be a limited time at the peer review meeting for comments 
from the public. Please inform ERG if you wish to make oral comments 
during the meeting.
    Information on Services for Individuals with Disabilities: EPA 
welcomes public attendance at the DDEF Peer Review Meeting and will 
make every effort to accommodate persons with disabilities. For 
information on access or services for individuals with disabilities, 
call ERG by calling (781) 674-7374 or toll free at (800) 803-2833 and 
speak to Laurie Waite; or send a facsimile to (781) 674-2906 (reference 
the ``DDEF Peer Review Meeting'' and include your name and contact 
information), or send an e-mail to [email protected] (reference the 
``DDEF Peer Review Meeting'' and include your name and contact 
information).

FOR FURTHER INFORMATION CONTACT: Dr. Michael W. Broder, Risk Assessment 
Forum, Office of the Science Advisor (8105R) at the following address: 
U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., 
Washington, DC 20460. His telephone number is (202) 564-3393. His e-
mail address is [email protected].
    Internet: The draft document can be downloaded from http://www.epa.gov/raf/DDEF/index.htm

SUPPLEMENTARY INFORMATION: This draft document outlines approaches for 
developing factors for interspecies and intraspecies extrapolation 
based on data describing toxicokinetics and/or toxicodynamics 
properties of particular chemical agent(s). It was developed to provide 
guidance for EPA staff in evaluating such data and/or information and 
to inform the regulated community and other interested parties about 
emerging EPA approaches to employ data to address areas of uncertainty.

    Dated: August 30, 2011.
Paul T. Anastas,
EPA Science Advisor.
[FR Doc. 2011-22660 Filed 9-6-11; 8:45 am]
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