[Federal Register Volume 76, Number 121 (Thursday, June 23, 2011)]
[Notices]
[Pages 36923-36924]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2011-15658]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES


Announcement of Availability of the Report on Carcinogens, 
Twelfth Edition

AGENCY: National Toxicology Program (NTP), National Institute of 
Environmental Health Sciences (NIEHS); National Institutes of Health 
(NIH).

[[Page 36924]]


ACTION: Availability of the Report on Carcinogens, Twelfth Edition 
(12th RoC).

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SUMMARY: The Department of Health and Human Services released the 12th 
RoC to the public on June 10, 2011. The report is available on the RoC 
Web site at: http://ntp.niehs.nih.gov/go/roc12 or in printed text or 
electronically from the Office of the RoC (see ADDRESSES below).

DATES: The 12th RoC will be available to the public on June 10, 2011.

ADDRESSES: Dr. Ruth Lunn, Director, Office of the RoC, NTP, NIEHS, P.O. 
Box 12233, MD K2-14, Research Triangle Park, NC 27709; telephone: (919) 
316-4637; FAX: (919) 541-0144; [email protected].

FOR FURTHER INFORMATION CONTACT: Questions or comments concerning the 
12th RoC should be directed to Dr. Ruth Lunn (telephone: (919) 361-4637 
or [email protected]).

SUPPLEMENTARY INFORMATION:

Background Information on the RoC

    The RoC is a Congressionally mandated document that identifies and 
discusses agents, substances, mixtures, or exposure circumstances 
(collectively referred to as ``substances'') that may pose a hazard to 
human health by virtue of their carcinogenicity. Substances are listed 
in the report as either known or reasonably anticipated to be human 
carcinogens. The listing of a substance in the RoC indicates a 
potential hazard, but does not establish the exposure conditions that 
would pose cancer risks to individuals in their daily lives. For each 
listed substance, the RoC provides information from cancer studies that 
support the listing as well as information about potential sources of 
exposure and current Federal regulations to limit exposures. Each 
edition of the RoC is cumulative, that is, it lists newly reviewed 
substances in addition to substances listed in the previous edition. 
Information about the RoC is available on the RoC Web site (http://ntp.niehs.nih.gov/go/roc12) or by contacting Dr. Lunn (see ADDRESSES 
above).
    The NTP prepares the RoC on behalf of the Secretary of Health and 
Human Services. For the 12th RoC, the NTP followed an established, 
multi-step process with multiple opportunities for public input, and 
used established criteria to evaluate the scientific evidence on each 
candidate substance under review (http://ntp.niehs.nih.gov/go/15208).

New Listings to the 12th RoC

    The 12th RoC contains 240 listings, some of which consist of a 
class of structurally related chemicals or agents. There are six new 
listings and two revised listings in this edition. The revised listings 
include (1) Formaldehyde, which was previously listed as reasonably 
anticipated to be a human carcinogen and is now listed as known to be a 
human carcinogen, and (2) certain glass wool fibers (inhalable). Glass 
wool (respirable) was first listed in the 7th RoC as reasonably 
anticipated to be a human carcinogen, but the scope of the listing 
changed and now certain glass wool fibers (inhalable) are listed as 
reasonably anticipated to be human carcinogens. The six new listings to 
the 12th RoC include one substance, aristolochic acids, listed as known 
to be human carcinogens, and five substances--captafol, cobalt-tungsten 
carbide: powders and hard metals, o-nitrotoluene, riddelliine, and 
styrene--listed as reasonably anticipated to be a human carcinogen.

    Dated: June 14, 2011.
Linda S. Birnbaum,
Director, National Institute of Environmental Health Sciences and 
National Toxicology Program.
[FR Doc. 2011-15658 Filed 6-22-11; 8:45 am]
BILLING CODE 4140-01-P