[Federal Register Volume 75, Number 245 (Wednesday, December 22, 2010)]
[Notices]
[Pages 80506-80507]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-32076]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30 Day-11-10GX]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail 
to [email protected]. Send written comments to CDC Desk Officer, Office of 
Management and Budget, Washington, DC 20503 or by fax to (202) 395-
5806. Written comments should be received within 30 days of this 
notice.

Proposed Project

    Persistence of Viable Influenza Virus in Aerosols--New--National 
Institute for Occupational Safety and Health (NIOSH), Centers for 
Disease Control and Prevention (CDC).

Background and Brief Description

    The National Institute for Occupational Safety and Health (NIOSH) 
is authorized to conduct research to advance the health and safety of 
workers under Section 20(a) (1) of the 1970 Occupational Safety and 
Health Act. Influenza continues to be a major public health concern 
because of the substantial health burden from seasonal influenza and 
the potential for a severe pandemic. Although influenza is known to be 
transmitted by infectious secretions, these secretions can be 
transferred from person to person in many different ways, and the 
relative importance of the different pathways is not known. The 
likelihood of the transmission of influenza virus by small infectious 
airborne particles produced during coughing and breathing is 
particularly unclear. The question of airborne transmission is 
especially important in healthcare facilities, where influenza patients 
tend to congregate during influenza season, because it directly impacts 
the infection control and personal protective measures that should be 
taken by healthcare workers. The purpose of this study is to measure 
the amount of viable influenza virus in airborne particles that are 
produced by patients when they cough, and the size and quantity of the 
particles carrying the virus. A better understanding of the amount of 
potentially infectious material released by patients and the size of 
the particles carrying the virus will assist in determining the 
possible role of airborne transmission in the spread of influenza and 
in devising measures to prevent it.
    Volunteer participants will be recruited by a test coordinator 
using a flyer describing the study. Interested potential participants 
will be screened using a short health questionnaire to verify that they 
have influenza-like symptoms and that they do not have any medical 
conditions that would preclude their participation. Based on a previous 
study using similar forms, we estimate that the health questionnaire 
will require about 5 minutes to complete. Qualified participants who 
agree to participate in the study will be asked to read and sign an 
informed consent form. Based on the previous study, we estimate that 
the informed consent form will take about 10 minutes to read and sign. 
Once the informed consent form is signed, the participant will have 
their oral temperature measured, two nasopharyngeal swabs will be 
collected, and the participant will be asked to cough into an aerosol 
particle collection system. These steps will take about 25 minutes. The 
airborne particles produced by the participant during coughing will be 
collected and tested.
    There are no costs to the respondents other than their time. The 
total estimated annual burden hours are 84.

                                        Estimated Annualized Burden Hours
----------------------------------------------------------------------------------------------------------------
                                                                                      Average
                                                     Number of       Number of      burden per     Total burden
      Type of respondent              Form          respondents    responses per   response  (in       hours
                                                                    respondent        hours)
----------------------------------------------------------------------------------------------------------------
Initial participants (phase 1)  Health                        44               1            5/60               4
                                 questionnaire.
Qualified participants (phase   Informed Consent              40               1           10/60               7
 1).                             form.
                                No form; Time                 40               1           25/60              17
                                 required for
                                 testing..
Initial participants (phase 2)  Health                        44               1            5/60               4
                                 questionnaire.
Qualified participants (phase   Informed Consent              40               1           10/60               7
 2).                             form.
                                No form; Time                 40               1           25/60              17
                                 required for
                                 testing..
Initial participants (phase 3)  Health                        44               1            5/60               4
                                 questionnaire.
Qualified participants (phase   Informed Consent              40               1           10/60               7
 3).                             form.
                                No form; Time                 40               1           25/60              17
                                 required for
                                 testing..
----------------------------------------------------------------------------------------------------------------



[[Page 80507]]

    Dated: December 16, 2010.
Catina Conner,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. 2010-32076 Filed 12-21-10; 8:45 am]
BILLING CODE 4163-18-P