[Federal Register Volume 75, Number 42 (Thursday, March 4, 2010)]
[Notices]
[Pages 9901-9902]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-4514]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[60Day-10-0736)


Proposed Data Collections Submitted for Public Comment and 
Recommendations

    In compliance with the requirement of section 3506(c)(2)(A) of the 
Paperwork Reduction Act of 1995 for opportunity for public comment on 
proposed data collection projects, the Centers for Disease Control and 
Prevention (CDC) will publish periodic summaries of proposed projects. 
To request more information on the proposed projects or to obtain a 
copy of the data collection plans and instruments, call 404-639-5960 or 
send comments to Maryam I. Daneshvar, CDC Acting Reports Clearance 
Officer, 1600 Clifton Road, MS D-74, Atlanta, GA 30333 or send an e-
mail to [email protected].
    Comments are invited on: (a) Whether the proposed collection of 
information is necessary for the proper performance of the functions of 
the agency, including whether the information shall have practical 
utility; (b) the accuracy of the agency's estimate of the burden of the 
proposed collection of information; (c) ways to enhance the quality, 
utility, and clarity of the information to be collected; and (d) ways 
to minimize the burden of the collection of information on respondents, 
including through the use of automated collection techniques or other 
forms of information technology. Written comments should be received 
within 60 days of this notice.

Proposed Project

    Human Smoking Behavior Study (OMB No. 0920-0736, exp. 3/31/2010)--
Reinstatement with Change--National Center for Chronic Disease 
Prevention and Health Promotion (NCCDPHP), Centers for Disease Control 
and Prevention (CDC).

Background and Brief Description

    Cigarettes are currently ranked as full-flavor, light or ultralight 
on the basis of machine-measured levels of smoke toxins (yield 
categories). The machine-based methods approximate human smoking 
patterns under controlled conditions but may not accurately reflect 
conditions of actual use, moreover, public health data have not 
consistently shown differences in health outcomes among smokers of 
cigarettes of different machine-smoked yield categories. Comparison of 
cigarette smoke emissions using machine-smoking methods will continue 
until something superior is developed, therefore, machine-smoking must 
be adequately informed to yield results that better reflect human 
smoking behavior.
    In 2007, the Centers for Disease Control and Prevention (CDC) 
received OMB approval for a study designed to elucidate patterns of 
human smoking behavior, quantify biomarkers of exposure to smoke toxins 
under conditions of actual use, and determine how smoking behavior 
modifies the relationship between cigarette yield category, biomarkers 
of exposure, and measures of cardiovascular reactivity. The study has 
been a collaborative endeavor involving the National Center for Chronic 
Disease Prevention and Health Promotion (NCCDPHP) and the National 
Center for Environmental Health (NCEH). Information has been collected 
from adult smokers of full-flavor, light and ultralight cigarettes, 
however, the target number of respondents was not achieved during the 
initial approval period.
    CDC requests OMB approval to reinstate the information collection 
after the expiration date (OMB No. 0920-0736, exp. 3/31/2010) in order 
to meet recruitment goals and complete the data analysis as outlined in 
the original approval. Respondents will be asked to participate in a 
laboratory-based descriptive study of smoking behavior and analysis of 
biomarkers of exposure. Respondents will make two visits to a 
laboratory for measurements and complete a brief smoking diary during 
the one-day interval between the two laboratory visits. Indicators of 
smoking behavior such as ventilation pore-blocking behavior, puff 
volume, puff duration, puff velocity and inter-puff interval will be 
assessed. Measures of exposure to be assessed include expired-air 
carbon monoxide boost, carcinogens, nicotine and its metabolites in 
urine, cotinine in saliva and solanesol in cigarette butts as an 
indicator of total smoke exposure.
    The goals of this project are to characterize the range of human 
smoking behavior for a variety of cigarette categories and machine-
smoked yields, and to estimate the levels of biomarkers of exposure 
with the various cigarette styles.
    CDC Requests OMB approval for two years. During this period there 
will be a reduction in total burden due to the limited number of 
respondents needed to complete the study. No changes to the data 
collection instruments or the estimated burden per response are 
proposed. Participation in the study is voluntary. There are no costs 
to respondents other than their time.

                                        Estimated Annualized Burden Hours
----------------------------------------------------------------------------------------------------------------
                                                                     Number of    Average burden
      Type of respondent            Form name        Number of     responses per   per response    Total burden
                                                    respondents     respondent      (in hours)      (in hours)
----------------------------------------------------------------------------------------------------------------
Adult Smokers.................  CATI Screener...             150               1            5/60              13
                                Visit 1 Screener              70               1            5/60               6
                                Smoking Diary...              61               1           10/60              10
                                Laboratory Visit              61               2               1             122
                               ---------------------------------------------------------------------------------
    Total.....................  ................  ..............  ..............  ..............             151
----------------------------------------------------------------------------------------------------------------



[[Page 9902]]

    Dated: February 25, 2010.
Maryam I. Daneshvar,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. 2010-4514 Filed 3-3-10; 8:45 am]
BILLING CODE 4163-18-P