[Federal Register Volume 74, Number 187 (Tuesday, September 29, 2009)]
[Pages 49874-49875]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E9-23504]



[FRL-8960-5; Docket ID No. EPA-HQ-ORD-2009-0217]

Draft Toxicological Review of Chloroprene: In Support of the 
Summary Information in the Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of public comment period.


SUMMARY: EPA is announcing a public comment period for the external 
review draft document titled, ``Toxicological Review of Chloroprene: In 
Support of Summary Information on the Integrated Risk Information 
System (IRIS)''. EPA intends to consider comments and recommendations 
from the public and the expert peer-review workshop, which will be 
scheduled at a later date and announced in the Federal Register, when 
EPA finalizes the draft document. The public comment period will 
provide opportunities for all interested parties to comment on the 
document. EPA intends to forward public comments submitted in 
accordance with this notice to the external peer-review panel prior to 
the meeting for their consideration.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination public review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    The draft document and EPA's peer-review charge are available via 
the Internet on the National Center for Environmental Assessment's 
(NCEA) home page under the Recent Additions and the Data and 
Publications menus at http://www.epa.gov/ncea. When finalizing the 
draft document, EPA intends to consider any public comments that EPA 
receives in accordance with this notice.

DATES: The 60-day public comment period begins September 29, 2009, and 
ends November 30, 2009. Technical comments should be in writing and 
must be received by EPA by November 30, 2009. EPA intends to submit 
comments from the public received by this date for consideration by the 
external peer review panel.

ADDRESSES: The draft ``Toxicological Review of Chloroprene: In Support 
of Summary Information on the Integrated Risk Information System 
(IRIS)'' is available via the Internet on the NCEA's home page under 
the Recent Additions and the Data and Publications menus at http://www.epa.gov/ncea. A limited number of paper copies are available from 
NCEA's Technical Information Staff, telephone: 703-347-8561; facsimile: 
703-347-8691. If you are requesting a paper copy, please provide your 
name, mailing address, and the document title, ``Toxicological Review 
of Chloroprene: In Support of Summary Information on the Integrated 
Risk Information System (IRIS)''.
    Comments may be submitted electronically via http://www.regulations.gov, by mail, by facsimile, or by hand delivery/
courier. Please follow the detailed instructions as provided in the 
SUPPLEMENTARY INFORMATION section of this notice.

FOR FURTHER INFORMATION CONTACT: For information on the public comment 
period, contact the Office of Environmental Information Docket; 
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
[email protected].
    If you have questions about the document, contact Allen Davis, 
Hazardous Pollutant Assessment Group (HPAG), National Center for 
Environmental Assessment, 109 T.W. Alexander Dr., Research Triangle 
Park, NC 27709; telephone: 919-541-3789; facsimile: 919-541-0245; or e-
mail: [email protected].


I. Summary of Information About the Integrated Risk Information System 

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at http://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
540 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of a risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic health effects, and oral slope 
factors and inhalation unit risks for carcinogenic effects. Combined 
with specific exposure information, government and private entities can 
use IRIS data to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.

II. How To Submit Technical Comments to the Docket at http://www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2009-
0217 by one of the following methods:
     http://www.regulations.gov: Follow the on-line 
instructions for submitting comments.
     E-mail: [email protected].
     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, EPA West Building, Room 3334, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information.
    If you provide comments by mail or hand delivery, please submit one 
unbound original with pages numbered consecutively, and three copies of 
the comments. For attachments, provide an index, number pages 
consecutively with the comments, and submit an unbound original and 
three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2009-0217. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the closing date will 
be marked ``late,'' and may only be considered if time permits. It is 
EPA's policy to include all comments it receives in the public docket 
without change and to make the comments available online at http://www.regulations.gov, including any personal information provided, 
unless a comment includes information

[[Page 49875]]

claimed to be Confidential Business Information (CBI) or other 
information whose disclosure is restricted by statute. Do not submit 
information that you consider to be CBI or otherwise protected through 
http://www.regulations.gov or e-mail. The http://www.regulations.gov 
Web site is an ``anonymous access'' system, which means EPA will not 
know your identity or contact information unless you provide it in the 
body of your comment. If you send an e-mail comment directly to EPA 
without going through http://www.regulations.gov, your e-mail address 
will be automatically captured and included as part of the comment that 
is placed in the public docket and made available on the Internet. If 
you submit an electronic comment, EPA recommends that you include your 
name and other contact information in the body of your comment and with 
any disk or CD-ROM you submit. If EPA cannot read your comment due to 
technical difficulties and cannot contact you for clarification, EPA 
may not be able to consider your comment. Electronic files should avoid 
the use of special characters, any form of encryption, and be free of 
any defects or viruses. For additional information about EPA's public 
docket visit the EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm.
    Docket: All documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other material, such 
as copyrighted material, will be publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in http://www.regulations.gov or in hard copy at the OEI Docket in the 
EPA Headquarters Docket Center.

    Dated: June 15, 2009.
Rebecca Clark,
Director, National Center for Environmental Assessment.
[FR Doc. E9-23504 Filed 9-28-09; 8:45 am]