[Federal Register Volume 74, Number 140 (Thursday, July 23, 2009)]
[Notices]
[Pages 36492-36493]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E9-17529]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[ATSDR-253]


Availability of Draft Toxicological Profile for Perfluoroalkyls

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice of availability.

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SUMMARY: This notice announces the availability of the draft 
toxicological profile for perfluoroalkyls, prepared by ATSDR, for 
review and comment.

DATES: In order to be considered, comments on this draft toxicological 
profile must be received on or before October 30, 2009. Comments 
received after the public comment period will be considered at the 
discretion of ATSDR on the basis of what is deemed to be in the best 
interest of the general public.

ADDRESSES: Requests for a printed copy of the draft toxicological 
profile should be sent to the attention of Ms. Olga Dawkins, Division 
of Toxicology and Environmental Medicine, Agency for Toxic Substances 
and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333. Electronic access to the document is also available at 
the ATSDR Web site: http://www.atsdr.cdc.gov/toxpro2.html.
    Requests for printed copies of the draft toxicological profile must 
be in writing and must specifically identify the toxicological profile 
that you wish to receive. ATSDR reserves the right to provide free of 
charge only one copy of each profile requested. In case of extended 
distribution delays, requestors will be notified.
    Comments regarding the draft toxicological profile for 
perfluoroalkyls should be sent to the attention of Ms. Nickolette 
Roney, Division of Toxicology and Environmental Medicine, Agency for 
Toxic Substances and Disease Registry, Mailstop F-62, 1600 Clifton 
Road, NE., Atlanta, Georgia 30333. Electronic comments may be sent to 
[email protected]. All comments sent electronically should 
contain the docket control number ATSDR-253 in the subject line.
    Written comments and other data submitted in response to this 
notice and the draft toxicological profile should bear the docket 
control number ATSDR-253. Send one copy of all comments and three 
copies of all supporting documents to Ms. Roney at the above address by 
the end of the comment period. Because all public comments regarding 
ATSDR toxicological profiles are available for public inspection, no 
confidential information should be submitted in response to this 
notice.

FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of 
Toxicology and Environmental Medicine, Agency for Toxic Substances and 
Disease Registry, Mailstop F-62, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333; telephone number (800) 232-4636 or (770) 488-3315.

SUPPLEMENTARY INFORMATION: This draft toxicological profile for 
perfluoroalkyls was prepared in accordance with guidelines developed by 
the Agency for Toxic Substances and Disease Registry and the 
Environmental Protection Agency (EPA) for the preparation of 
toxicological profiles. The original guidelines were published in the 
Federal Register on April 17, 1987. While perfluoroalkyls are not found 
on the ATSDR Priority List of Hazardous Substances, ATSDR has 
determined that a profile for these substances was necessary because 
data indicate that some perfluoroalkyls are found in the blood of the 
United States general population and in the environment. The agency 
also determined that it was important to characterize the current 
available information regarding the health effects from exposure to 
perfluoroalkyls in order to support and inform public health responses 
and activities by ATSDR and others. This profile will be revised and 
republished as necessary.
    Section 104(i)(3) of the Comprehensive Environmental Response, 
Compensation, and Liability Act [42 U.S.C. 9604(i)(3)] outlines the 
content of the toxicological profiles. Each profile includes an 
examination, a summary, and an interpretation of available 
toxicological information and epidemiologic evaluations. This 
information and these data are to be used to identify the levels of 
significant human exposure to a substance and the associated health 
effects. The profiles must also include a determination of whether 
adequate information on the health effects of each substance is 
available or in the process of development. When adequate information 
is not available, ATSDR, in cooperation with the National Toxicology 
Program (NTP), will initiate a research program to determine these 
health effects.
    Although key studies for this substance were considered during the 
profile development process, this Federal Register notice solicits any 
additional studies, particularly unpublished data and ongoing studies, 
which will be evaluated for possible addition to the profile now or in 
the future.

[[Page 36493]]

    The following draft toxicological profile will be made available to 
the public on or about July 6, 2009.

 
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            Document                Toxicological profile      CAS No.
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1...............................  PERFLUOROALKYLS.........   000375-22-4
                                                             000335-67-1
                                                             001763-23-1
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    All profiles issued as ``Draft for Public Comment'' represent 
ATSDR's best efforts to provide important toxicological information on 
priority substances. We are seeking public comments and additional 
information that may be used to supplement this profile. ATSDR remains 
committed to providing a public comment period for these documents as 
the best means to serve public health and our clients.

Ken Rose,
Director, Office of Policy, Planning, and Evaluation, National Center 
for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. E9-17529 Filed 7-22-09; 8:45 am]
BILLING CODE 4163-70-P