[Federal Register Volume 73, Number 244 (Thursday, December 18, 2008)]
[Notices]
[Pages 77026-77027]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E8-30024]



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DEPARTMENT OF HEALTH AND HUMAN SERVICES


National Toxicology Program (NTP); Office of Liaison, Policy and 
Review; Meeting of the NTP Board of Scientific Counselors Technical 
Reports Review Subcommittee

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH).

ACTION: Meeting announcement and request for comments.

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SUMMARY: Pursuant to Public Law 92-463, notice is hereby given of a 
meeting of the NTP Board of Scientific Counselors (BSC) Technical 
Reports Review Subcommittee (TRR Subcommittee). The primary agenda 
topic is the peer review of the findings and conclusions presented in 
six draft NTP Technical Reports of rodent toxicology and 
carcinogenicity studies in conventional rats and mice. The TRR 
Subcommittee meeting is open to the public with time scheduled for oral 
public comment. The NTP also invites written comments on the draft 
reports (see ``Request for Comments'' below). The TRR Subcommittee 
deliberations on the draft reports will be reported to the NTP BSC at a 
future meeting.

DATES: The TRR Subcommittee meeting will be held on February 25, 2009. 
All individuals who plan to attend are encouraged to register online by 
February 18, 2009, at the NTP Web site (http://ntp.niehs.nih.gov/go/15833). The draft reports should be posted by January 14, 2009. Written 
comments on the draft reports should be received by February 11, 2009. 
Persons needing interpreting services in order to attend should contact 
301-402-8180 (voice) or 301-435-1908 (TTY). For other accommodations 
while on the NIEHS campus, contact 919-541-2475 or e-mail 
[email protected]. Requests should be made at least 7 days in 
advance of the event.

ADDRESSES: The TRR Subcommittee meeting will be held in the Rodbell 
Auditorium, Rall Building at the NIEHS, 111 T. W. Alexander Drive, 
Research Triangle Park, NC 27709. Public comments and any other 
correspondence should be submitted to Dr. Barbara Shane, Executive 
Secretary for the NTP BSC (NTP Office of Liaison, Policy and Review, 
NIEHS, P.O. Box 12233, MD A3-01, Research Triangle Park, NC 27709; 
courier address: 530 Davis Drive, Durham, NC 27713; telephone: 919-541-
4253, fax: 919-541-0295; or e-mail: [email protected]).

SUPPLEMENTARY INFORMATION:

Background

    The primary agenda topic is the peer review of the findings and 
conclusions of six draft NTP Technical Reports of rodent toxicology and 
carcinogenicity studies (see Preliminary Agenda below).

Attendance and Registration

    The meeting is scheduled for February 25, 2009, from 8:30 a.m. to 
adjournment and is open to the public with attendance limited only by 
the space available. Individuals who plan to attend are encouraged to 
register online at the NTP Web site by February 18, 2009 (http://ntp.niehs.nih.gov/go/15833) to facilitate access to the NIEHS campus. A 
photo ID is required to access the NIEHS campus. The NTP is making 
plans to videocast the meeting through the Internet at http://www.niehs.nih.gov/news/video/live.

Availability of Meeting Materials

    A copy of the preliminary agenda, committee roster, and any 
additional information, when available, will be posted on the NTP Web 
site (http://ntp.niehs.nih.gov/go/15833) or may be requested in 
hardcopy from the Executive Secretary (see ADDRESSES above). The draft 
reports should be posted on the NTP Web site by January 14, 2009. 
Following the meeting, summary minutes will be prepared and made 
available on the NTP Web site.

Request for Comments

    The NTP invites written comments on the draft reports, which should 
be received by February 11, 2009, to enable review by the TRR 
Subcommittee and NTP staff prior to the meeting. Persons submitting 
written comments should include their name, affiliation, mailing 
address, phone, e-mail, and sponsoring organization (if any) with the 
document. Written comments received in response to this notice will be 
posted on the NTP Web site, and the submitter will be identified by 
name, affiliation, and/or sponsoring organization.
    Public input at this meeting is also invited and time is set aside 
for the presentation of oral comments on the draft reports. Each 
organization is allowed one time slot per draft report. At least 7 
minutes will be allotted to each speaker, and if time permits, may be 
extended to 10 minutes at the discretion of the chair. Persons wishing 
to make an oral presentation are asked to notify Dr. Barbara Shane via 
online registration at http://ntp.niehs.nih.gov/go/15833, phone, or e-
mail (see ADDRESSES above) by February 18, 2009, and if possible, to 
send a copy of the statement or talking points at that time. Written 
statements can supplement and may expand the oral presentation. 
Registration for oral comments will also be available at the meeting, 
although time allowed for presentation by on-site registrants may be 
less than that for pre-registered speakers and will be determined by 
the number of persons who register on-site.

Background Information on the NTP Board of Scientific Counselors

    The NTP BSC is a technical advisory body comprised of scientists 
from the public and private sectors who provide primary scientific 
oversight to the overall program and its centers. Specifically, the BSC 
advises the NTP on matters of scientific program content, both present 
and future, and conducts periodic review of the program for the 
purposes of determining and advising on the scientific merit of its 
activities and their overall scientific quality. The TRR Subcommittee 
is a standing subcommittee of the BSC. BSC members are selected from 
recognized authorities knowledgeable in fields such as toxicology, 
pharmacology, pathology, biochemistry, epidemiology, risk assessment, 
carcinogenesis, mutagenesis, molecular biology, behavioral toxicology 
and neurotoxicology, immunotoxicology, reproductive toxicology or 
teratology, and biostatistics. Its members are invited to serve 
overlapping terms of up to four years. BSC and TRR Subcommittee 
meetings are held annually or biannually.

    Dated: December 9, 2008.
Samuel H. Wilson,
Acting Director, National Institute of Environmental Health Sciences 
and National Toxicology Program.

Preliminary Agenda

National Toxicology Program Board of Scientific Counselors

Technical Reports Review Subcommittee Meeting

February 25, 2009

National Institute of Environmental Health Sciences

Rodbell Auditorium, Rall Building

111 T.W. Alexander Drive, Research Triangle Park, NC

Technical Reports (TR) Scheduled for Review

     TR 559 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 
31508-00-6)
    [cir] Insulating fluid for electronics; a representative mono-ortho 
substituted PCB evaluated as part of a series of

[[Page 77027]]

studies to assess the carcinogenic potency of a class of agents with 
dioxin-like activity
     TR 558 3,3',4,4'-Tetrachloroazobenzene (CASRN 14047-09-7)
    [cir] Impurity in dichloroaniline and in herbicides derived from 
dichloroaniline; evaluated as part of the Dioxin Toxic Equivalency 
Factor Evaluation for compounds with dioxin-like activity
     TR 560 Androstenedione (CASRN 63-05-8)
    [cir] Dietary supplement that was used by athletes during training, 
but now is banned for over-the-counter sale
     TR 557 [beta]-Myrcene (CASRN 123-35-3)
    [cir] Intermediate in the commercial production of terpene 
alcohols, which are intermediates in the production of aroma and 
flavoring chemicals; used as a scent in cosmetics and soaps and as a 
flavoring additive in food and beverages; major constituent of hop and 
bay oils
     TR 555 Tetralin (CASRN 119-64-2)
    [cir] Used as an industrial solvent for paints, waxes, polishes, 
pesticides, rubber, asphalt, and aromatic hydrocarbons; used as an 
insecticide; derived from naphthalene
     TR 562 Goldenseal Root Powder (CASRN goldensealRT)
    [cir] Natural herbal remedy for which there is little or no 
toxicity data

 [FR Doc. E8-30024 Filed 12-17-08; 8:45 am]
BILLING CODE 4140-01-P