[Federal Register Volume 72, Number 206 (Thursday, October 25, 2007)]
[Notices]
[Pages 60673-60677]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E7-21018]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[ATSDR-235]


Proposed Substances To Be Evaluated for Set 22 Toxicological 
Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Request for comments on the proposed substances to be evaluated 
for Set 22 toxicological profiles.

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SUMMARY: This notice announces the list of proposed substances that 
will be evaluated for CERCLA Set 22

[[Page 60674]]

toxicological profile development. ATSDR's Division of Toxicology and 
Environmental Medicine is soliciting public nominations from the list 
of proposed substances to be evaluated for toxicological profile 
development. ATSDR also will consider the evaluation of any additional 
substances that may have public health implications.

DATES: Nominations must be submitted within 30 days of the publication 
of this notice. The 30-day period begins October 26th, 2007 and ends 
November 26th, 2007.

ADDRESSES: Nominations may be submitted electronically, by mail, or by 
facsimile. Refer to the section Submission of Nominations (below) for 
specific addresses and/or the facsimile number.

FOR FURTHER INFORMATION CONTACT: Contact Commander Jessilynn B. Taylor, 
Division of Toxicology and Environmental Medicine, Agency for Toxic 
Substances and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., 
Atlanta, Georgia 30333, telephone (770) 488-3313.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization 
Act of 1986 (SARA) [42 U.S.C. 9601 et seq.] amended the Comprehensive 
Environmental Response, Compensation, and Liability Act of 1980 (CERCLA 
or Superfund) [42 U.S.C. 9601 et seq.] by establishing certain 
requirements for ATSDR and the U.S. Environmental Protection Agency 
(EPA) with regard to hazardous substances that are most commonly found 
at facilities on the CERCLA National Priorities List (NPL). Among these 
statutory requirements is a mandate for the Administrator of ATSDR to 
prepare toxicological profiles for each substance included on the 
Priority List of Hazardous Substances. This list has identified 275 
hazardous substances that ATSDR and EPA determined pose the most 
significant potential threat to human health. The availability of the 
revised list of the 275 priority substances was announced in the 
Federal Register on December 7, 2005 (70 FR 702840). For prior versions 
of the list of substances, see Federal Register notices dated April 17, 
1987 (52 FR 12866); October 20, 1988 (53 FR 41280); October 26, 1989 
(54 FR 43619); October 17, 1990 (55 FR 42067); October 17, 1991 (56 FR 
52166); October 28, 1992 (57 FR 48801); February 28, 1994 (59 FR 9486); 
April 29, 1996 (61 FR 18744; November 17, 1997 (62 FR 61332); October 
21, 1999 (64 FR 56792); October 25, 2001 (66 FR 54014) and November 7, 
2003 (68 FR 63098).

Proposed Substances To Be Evaluated for Set 22 Toxicological Profiles

    Each year, ATSDR develops a list of priority substances that will 
be evaluated for toxicological profile development. This list was 
compiled, on the basis of ATSDR's Priority List of Hazardous 
Substances, with consideration of the amount of relevance of newly 
published scientific literature. The following 73 substances will be 
evaluated:

------------------------------------------------------------------------
                                 Substance name               CAS No.
------------------------------------------------------------------------
1.....................  PERFLUOROOCTANOIC ACID..........             (1)
                        PERFLUOROCYL SULFONATES.........             (1)
2.....................  MERCURY.........................     007439-97-6
                        METHYLMERCURY...................     022967-92-6
                        MERCURIC CHLORIDE...............     007487-94-7
3.....................  POLYCHLORINATED BIPHENYLS.......     001336-36-3
                        AROCLOR 1254....................     011097-69-1
                        AROCLOR 1260....................     011096-82-5
                        AROCLOR 1248....................     012672-29-6
                        AROCLOR 1242....................     053469-21-9
                        AROCLOR.........................     012767-79-2
                        AROCLOR 1221....................     011104-28-2
                        AROCLOR 1016....................     012674-11-2
                        AROCLOR 1232....................     011141-16-5
                        AROCLOR 1240....................     071328-89-7
                        TETRACHLOROBIPHENYL.............     026914-33-0
4.....................  CADMIUM.........................     007440-43-9
5.....................  POLYCYCLIC AROMATIC HYDROCARBONS     130498-29-2
                        BENZO(A)PYRENE..................     000050-32-8
                        BENZO(B)FLUORANTHENE............     000205-99-2
                        DIBENZO(A,H)ANTHRACENE..........     000053-70-3
                        BENZO(A)ANTHRACENE..............     000056-55-3
                        BENZO(K)FLUORANTHENE............     000207-08-9
                        BENZOFLUORANTHENE...............     056832-73-6
                        FLUORANTHENE....................     000206-44-0
                        CHRYSENE........................     000218-01-9
                        ACENAPHTHENE....................     000083-32-9
                        INDENO(1,2,3-CD)PYRENE..........     000193-39-5
                        BENZOPYRENE.....................     073467-76-2
                        PHENANTHRENE....................     000085-01-8
                        PYRENE..........................     000129-00-0
                        FLUORENE........................     000086-73-7
                        ANTHRACENE......................     000120-12-7
                        BENZO(A)FLUORANTHENE............     000203-33-8
                        BENZO(GHI)PERYLENE..............     000191-24-2
                        ACENAPHTHYLENE..................     000208-96-8
                        BENZO(J)FLUORANTHENE............     000205-82-3
                        BENZO(E)PYRENE..................     000192-97-2
                        BENZOPERYLENE...................     011057-45-7
                        BENZO(B)ANTHRACENE..............     000092-24-0
                        DIBENZ(A,J)ANTHRACENE...........     000224-41-9
                        BENZO(GHI)FLUORANTHENE..........     000203-12-3
                        1-METHYLPYRENE..................     002381-21-7

[[Page 60675]]

 
6.....................  CHLOROFORM......................     000067-66-3
7.....................  DDT, P,P'-......................     000050-29-3
                        DDE, P,P'-......................     000072-55-9
                        DDD, P,P'-......................     000072-54-8
                        DDT, O,P'-......................     000789-02-6
                        DDD, O,P'-......................     000053-19-0
                        DDE, O,P'-......................     003424-82-6
8.....................  TRICHLOROETHYLENE...............     000079-01-6
9.....................  IELDRIN.........................     000060-57-1
                        ALDRIN..........................     000309-00-2
10....................  CHROMIUM, HEXAVALENT............     018540-29-9
                        CHROMIUM(VI) OXIDE..............     001333-82-0
                        CHROMIUM........................     007440-47-3
                        CHROMIUM TRIOXIDE...............     007738-94-5
                        CHROMIUM, TRIVALENT.............     016065-83-1
11....................  CHLORDANE.......................     000057-74-9
                        CIS-CHLORDANE...................     005103-71-9
                        TRANS-CHLORDANE.................     005103-74-2
                        OXYCHLORDANE....................     027304-13-8
                        GAMMA-CHLORDENE.................     056641-38-4
                        CHLORDANE, TECHNICAL............     012789-03-6
                        ALPHA-CHLORDENE.................     056534-02-2
                        NONACHLOR, TRANS-...............     039765-80-5
                        NONACHLOR, CIS-.................     005103-73-1
                        CHLORDENE.......................     003734-48-3
12....................  HEXACHLOROBUTADIENE.............     000087-68-3
13....................  COAL TAR CREOSOTE...............     008001-58-9
                        COAL TARS.......................     008007-45-2
                        COAL TAR PITCH..................     065996-93-2
14....................  BENZIDINE.......................     000092-87-5
15....................  TOXAPHENE.......................     008001-35-2
16....................  TETRACHLOROETHYLENE.............     000127-18-4
17....................  1,2-DIBROMOETHANE...............     000106-93-4
18....................  DISULFOTON......................     000298-04-4
19....................  3,3'-DICHLOROBENZIDINE..........     000091-94-1
20....................  BERYLLIUM.......................     007440-41-7
21....................  ENDRIN..........................     000072-20-8
                        ENDRIN KETONE...................     053494-70-5
                        ENDRIN ALDEHYDE.................     007421-93-4
22....................  1,2-DIBROMO-3-CHLOROPROPANE.....     000096-12-8
                        DIBROMOCHLOROPROPANE............     067708-83-2
23....................  PENTACHLOROPHENOL...............     000087-86-5
24....................  DI-N-BUTYL PHTHALATE............     000084-74-2
25....................  ENDOSULFAN SULFATE..............     001031-07-8
                        ENDOSULFAN......................     000115-29-7
                        ENDOSULFAN, ALPHA...............     000959-98-8
                        ENDOSULFAN, BETA................     033213-65-9
26....................  METHOXYCHLOR....................     000072-43-5
27....................  METHANE.........................     000074-82-8
28....................  TOLUENE.........................     000108-88-3
29....................  2-HEXANONE......................     000591-78-6
30....................  2,3,7,8-TETRACHLORODIBENZO-P-        001746-01-6
                         DIOXIN.
                        HEXACHLORODIBENZO-P-DIOXIN......     034465-46-8
                        HEPTACHLORODIBENZO-P-DIOXIN.....     037871-00-4
                        TETRACHLORODIBENZO-P-DIOXIN.....     041903-57-5
                        PENTACHLORODIBENZO-P-DIOXIN.....     036088-22-9
                        1,2,3,4,6,7,8-HEPTACHLORODIBENZO-    035822-46-9
                         P-DIOXIN.
                        OCTACHLORODIBENZO-P-DIOXIN......     003268-87-9
                        1,2,3,6,7,8-HEXACHLORODIBENZO-P-     057653-85-7
                         DIOXIN.
                        1,2,3,4,7,8-HEXACHLORODIBENZO-P-     039227-28-6
                         DIOXIN.
                        1,2,3,7,8,9-HEXACHLORODIBENZO-P-     019408-74-3
                         DIOXIN.
                        1,2,3,7,8-PENTACHLORODIBENZO-P-      040321-76-4
                         DIOXIN.
31....................  DI(2-ETHYLHEXYL)PHTHALATE.......     000117-81-7
32....................  1,1-DICHLOROETHENE..............     000075-35-4
33....................  METHYLENE CHLORIDE..............     000075-09-2
34....................  2,4,6-TRINITROTOLUENE...........     000118-96-7
35....................  BROMODICHLOROETHANE.............     000683-53-4
36....................  1,2-DICHLOROETHANE..............     000107-06-2
37....................  2,4,6-TRICHLOROPHENOL...........     000088-06-2
                        TETRACHLOROPHENOL...............     025167-83-3
                        2,4-DICHLOROPHENOL..............     000120-83-2
                        2,4,5-TRICHLOROPHENOL...........     000095-95-4
                        2-CHLOROPHENOL..................     000095-57-8
                        2,3,4,5-TETRACHLOROPHENOL.......     004901-51-3

[[Page 60676]]

 
                        2,3,5,6-TETRACHLOROPHENOL.......     000935-95-5
                        2,3,4,6-TETRACHLOROPHENOL.......     000058-90-2
                        4-CHLOROPHENOL..................     000106-48-9
                        CHLOROPHENOL....................     025167-80-0
38....................  2,4-DINITROPHENOL...............     000051-28-5
39....................  BIS(2-CHLOROETHYL) ETHER........     000111-44-4
40....................  ASBESTOS........................     001332-21-4
                        CHRYSOTILE ASBESTOS.............     012001-29-5
                        AMOSITE ASBESTOS................     012172-73-5
41....................  HEXACHLOROBENZENE...............     000118-74-1
42....................  RADIUM-226......................     013982-63-3
                        RADIUM..........................     007440-14-4
                        RADIUM-228......................     015262-20-1
                        RADIUM-224......................     013233-32-4
43....................  2,4-DINITROTOLUENE..............     000121-14-2
                        DINITROTOLUENE..................     025321-14-6
                        2,6-DINITROTOLUENE..............     000606-20-2
44....................  ETHION..........................     000563-12-2
45....................  THORIUM.........................     007440-29-1
                        THORIUM-230.....................     014269-63-7
                        THORIUM-228.....................     014274-82-9
46....................  4,6-DINITRO-O-CRESOL............     000534-52-1
47....................  RADON...........................     010043-92-2
                        RADON-222.......................     014859-67-7
                        RADON-220.......................     022481-48-7
48....................  CHLOROBENZENE...................     000108-90-7
49....................  N-NITROSODI-N-PROPYLAMINE.......     000621-64-7
50....................  MANGANESE.......................     007439-96-5
                        MANGANESE DIOXIDE...............     001313-13-9
51....................  POLONIUM-210....................     013981-52-7
52....................  LEAD-210........................     014255-04-0
53....................  CHLORPYRIFOS....................     002921-88-2
54....................  NEPTUNIUM-237...................     013994-20-2
55....................  CHLORDECONE.....................     000143-50-0
                        MIREX...........................     002385-85-5
56....................  S,S,S-TRIBUTYL                       000078-48-8
                         PHOSPHOROTRITHIOATE.
57....................  BROMINE.........................     007726-95-6
58....................  1,2,3-TRICHLOROBENZENE..........     000087-61-6
59....................  DICOFOL.........................     000115-32-2
60....................  PARATHION.......................     000056-38-2
61....................  TRICHLOROFLUOROETHANE...........     027154-33-2
62....................  TRIFLURALIN.....................     001582-09-8
63....................  4,4'-METHYLENEBIS(2-                 000101-14-4
                         CHLOROANILINE).
64....................  PENTACHLOROBENZENE..............     000608-93-5
65....................  1,1-DICHLOROETHANE..............     000075-34-3
66....................  1,1,2-TRICHLOROETHANE...........     000079-00-5
67....................  1,2,3,4,6,7,8,9-                     039001-02-0
                         OCTACHLORODIBENZOFURAN.
                        HEPTACHLORODIBENZOFURAN.........     038998-75-3
                        2,3,4,7,8-                           057117-31-4
                         PENTACHLORODIBENZOFURAN.
                        HEXACHLORODIBENZOFURAN..........     055684-94-1
                        PENTACHLORODIBENZOFURAN.........     030402-15-4
                        2,3,7,8-TETRACHLORODIBENZOFURAN.     051207-31-9
                        DIBENZOFURANS, CHLORINATED......     042934-53-2
                        1,2,3,4,6,7,8-                       067562-39-4
                         HEPTACHLORODIBENZOFURAN.
                        1,2,3,7,8,9-                         072918-21-9
                         HEXACHLORODIBENZOFURAN.
                        TETRACHLORODIBENZOFURAN.........     030402-14-3
                        1,2,3,6,7,8-                         057117-44-9
                         HEXACHLORODIBENZOFURAN.
                        1,2,3,4,7,8-                         070648-26-9
                         HEXACHLORODIBENZOFURAN.
                        2,3,4,6,7,8-                         060851-34-5
                         HEXACHLORODIBENZOFURAN.
                        1,2,3,7,8-                           057117-41-6
                         PENTACHLORODIBENZOFURAN.
                        1,2,3,4,7,8,9-                       055673-89-7
                         HEPTACHLORODIBENZOFURAN.
68....................  TRICHLOROETHANE.................     025323-89-1
69....................  HEXACHLOROCYCLOPENTADIENE.......     000077-47-4
70....................  1,2-DIPHENYLHYDRAZINE...........     000122-66-7
71....................  NANOMATERIALS...................  ..............
72....................  VANADIUM........................     007440-62-2
73....................  FORMALDEHYDE....................    000050-00-0
------------------------------------------------------------------------
(1) Various.


[[Page 60677]]

Submission of Nominations for the Evaluation Set 22

    Proposed Substances: Today's notice also invites voluntary public 
nominations for substances not listed in this notice. Nominations are 
most useful if they include the nominator, including full name, title, 
affiliation, email address, and telephone number.
    ATSDR will evaluate all data and information associated with 
nominated substances and will determine the final list of substances 
that will be chosen for toxicological profile development. Substances 
will be chosen according to ATSDR's specific guidelines for selection, 
found in the Selection Criteria announced in the Federal Register on 
May 7th, 1993 (87 FR 27288).
    Please submit nominations by one of the following methods:
     E-mail: [email protected].
     Fax: 770.488.4178.
     Mail: CDR Jessilynn Taylor, 1600 Clifton Rd, NE., MS F32, 
Atlanta, GA, 30333.
    Please ensure that your comments are submitted within the specified 
nomination period. Nominations received after the closing date will be 
marked as late and may be considered only if time permits.

    Dated: October 19, 2007.
Ken Rose,
Director, Office of Policy, Planning and Evaluation, National Center 
for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
 [FR Doc. E7-21018 Filed 10-24-07; 8:45 am]
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