[Federal Register Volume 72, Number 17 (Friday, January 26, 2007)]
[Notices]
[Pages 3866-3867]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E7-1282]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Proposed Collection; Comment Request; Phase II of a Prospective 
Cohort Study of Diet and Cancer in Members of the American Association 
of Retired Persons

SUMMARY: In compliance with the requirement of Section 3506(c)(2)(A) of 
the Paperwork Reduction Act of 1995, for opportunity for public comment 
on proposed data collection projects, the National Cancer Institute 
(NCI), the National Institutes of Health (NIH) will publish periodic 
summaries of proposed projects to be submitted to the Office of 
Management and Budget (OMB) for review and approval.
    Proposed Collection: Title: Phase II of A Prospective Cohort Study 
of Diet and Cancer in Members of the American Association of Retired 
Persons. Type of Information Collection Request: New. Need and Use of 
Information Collection: The specific objectives of the current study 
are to: (1) Examine prospectively the relation between diet and major 
cancers (especially those of the breast, colorectal, prostate, and non-
Hodgkin's lymphoma; (2) in a series of pilot studies, evaluate the 
quality and completeness of dietary data collected from automated web-
based dietary assessment instruments, individually and collectively, in 
a large cohort, and; (3) in a calibration substudy, compare energy 
expenditure (measured by doubly labeled water) and protein and 
potassium intakes (measured by 24-hour urinary nitrogen and potassium 
excretion) with intakes of energy, protein, and potassium as reported 
on web-based, automated 24-Hour Dietary Record (24HR), an automated 
Diet History Questionnaire (DHQ), and an automated DHQ adjusted by 
automated 7-Day Food Lists (7DFLs) to assess measurement error 
structure in the instruments.
    The proposed study will build on the existing Prospective Study of 
Diet and Cancer in members of the American Association of Retired 
Persons by updating exposure information in the existing cohort and 
allowing for continued tracking and follow-up; (2) expanding the cohort 
by recruiting additional participants and surveying their diet and 
other exposures. In addition to the 566,403 persons from the original 
cohort, a new cohort of 2.5 million 50-59 year olds from the same 
states as the original AARP cohort, and 4 million 50-69 year olds from 
8 new states will be contacted as part of the recruitment and data 
collection effort. Phase II will apply the latest technology to use 
web-based data collection instruments for economical and efficient 
assessment of dietary exposures of study participants. This uniquely 
designed cohort study has a capacity greater than that of any previous 
study for evaluating connections between dietary factors and major 
cancers.
    Frequency of Response: The frequency of response is dependent on 
the instrument and the portion of the study that the respondent is 
participating in (pilot, main study, and/or calibration substudy), as 
described in the table below. Affected Public: Individuals. Type of 
Respondents: U.S. adults (person ages 50-85).
    The annual reporting burden is as follows:

      Table A.--Annualized Burden Estimates for the Phase II NIH-AARP Diet and Health Study Data Collection
----------------------------------------------------------------------------------------------------------------
                                                     Estimated
                Type of response                     number of     Frequency of    Average time     Annual hour
                                                    respondents      response      per response       burden
----------------------------------------------------------------------------------------------------------------
Pilot Studies:
    Personal characteristics Questionnaire (PCQ)            Completed one time; counted in main study.
                                                 ---------------------------------------------------------------
    Diet History Questionnaire (DHQ)............            Completed one time; counted in main study.
                                                 ---------------------------------------------------------------
    24-Hour Food Recall.........................           1,500               3            0.42           1,890
    7-Day Food List.............................           1,500               1            1.75           2,625
    Other Dietary Assessment Instruments........           1,500               1            0.25              75
                                                 ---------------------------------------------------------------
        Pilot Study Total.......................           1,500  ..............  ..............           4,590

[[Page 3867]]

 
Main Study:
    PCQ.........................................       1,710,403               1            0.25         427,601
    DHQ.........................................       1,710,403               1             1.0       1,710,403
    24-Hour Food Recall.........................       1,710,403               6            0.42       4,310,216
    7-Day Food List.............................       1,710,403               1            1.75       2,993,205
    Other Dietary Assessment Instruments........       1,710,403               1             .25         427,601
                                                 ---------------------------------------------------------------
        Main Study Total........................       1,710,403  ..............  ..............       9,869,026
Calibration Substudy:
                                                 ---------------------------------------------------------------
    PCQ.........................................            Completed one time; counted in main study.
                                                 ---------------------------------------------------------------
    DHQ.........................................            Completed one time; counted in main study.
                                                 ---------------------------------------------------------------
    24-Hour Food Recall.........................             400               2            0.42            1344
    7-Day Food List.............................             400               1            1.75            1400
    Physical Activity Questionnaire.............             400               1            0.25             100
                                                 ---------------------------------------------------------------
        Calibration Substudy Total..............             400  ..............  ..............           2,844
----------------------------------------------------------------------------------------------------------------

    There are no Capital, Operating, or Maintenance Costs to report.
    Request for Comments: Written comments and/or suggestions from the 
public and affected agencies are invited on one or more of the 
following points: (1) Whether the proposed collection of information is 
necessary for the proper performance of the function of the agency, 
including whether the information will have practical utility; (2) The 
accuracy of the agency's estimate of the burden of the proposed 
collection of information, including the validity of the methodology 
and assumptions used; (3) Ways to enhance the quality, utility, and 
clarity of the information to be collected; and (4) Ways to minimize 
the burden of the collection of information on those who are to 
respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.

FOR FURTHER INFORMATION CONTACT: To request more information on the 
proposed project or to obtain a copy of the data collection plans and 
instruments, contact Arthur Schatzkin, M.D., Dr. P.H., Nutritional 
Epidemiology Branch, Division of Cancer Epidemiology and Genetics, 
National Cancer Institute, NIH, DHHS, 6120 Executive Blvd., EPS-MSC 
7242, Bethesda, MD, 20892, U.S.A. or call non-toll-free number 301-594-
2931 or e-mail your request, including your address to: 
[email protected].
    Comments Due Date: Comments regarding this information collection 
are best assured of having their full effect if received within 60 days 
of the date of this publication.

    Dated: January 16, 2007.
Rachelle Ragland-Greene,
NCI Project Clearance Liaison, National Institutes of Health.
[FR Doc. E7-1282 Filed 1-25-07; 8:45 am]
BILLING CODE 4140-01-P