[Federal Register Volume 72, Number 3 (Friday, January 5, 2007)]
[Notices]
[Pages 566-567]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E6-22579]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30Day-07-425X]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail 
to [email protected]. Send written comments to CDC Desk Officer, Office of 
Management and Budget, Washington, DC or by fax to (202) 395-6974. 
Written comments should be received within 30 days of this notice.

Proposed Project

    The National Centers for Autism and Developmental Disabilities 
Research and Epidemiology (CADDRE) Study--New--National Center on Birth 
Defects and Developmental Disabilities (NCBDDD), Centers for Disease 
Control and Prevention (CDC).

Background and Brief Description

    The Children's Health Act of 2000 mandated CDC to establish autism 
surveillance and research programs to address the number, incidence, 
correlates, and causes of autism and related disabilities. Under the 
provisions of this act, CDC funded 5 CADDRE centers: California 
Department of Health and Human Services, Colorado Department of Public 
Health and Environment, Johns Hopkins University, the University of 
Pennsylvania, and the University of North Carolina at Chapel Hill. CDC 
National Center on Birth Defects and Developmental Disabilities will 
participate as the 6th site.
    The purpose of this program is to establish a multi-site, 
collaborative epidemiological investigation of possible causes of 
autism spectrum disorders. Children with autism spectrum disorders will 
be compared to children with other developmental problems, referred to 
as the neurodevelopmentally impaired group (NIC), as well as children 
who do not have developmental problems, referred to as the subcohort.
    Data collection methods will consist of the following: (1) Medical 
record review of the child participant and biological mother; (2) self-
administered

[[Page 567]]

Questionnaires; (3) buccal cell collection; (4) a telephone interview 
of the biological mother and/or primary caregiver; (5) a child 
development evaluation (more comprehensive for case participants than 
for the control group participants); (6) parent-child development 
interview (for case participants only); (7) a physical exam of the 
child; (8) biological sampling of the child (blood and hair); and (9) 
biological sampling of the biological parents (blood only).
    There are no costs to respondents other than their time. The total 
estimated annualized burden is 30,103 hours.

                                        Estimated Annualized Burden Hours
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                                                                                      Average
                                                     Number of       Number of      burden per     Total burden
                   Respondents                      respondents    responses per   response  (In       hours
                                                                    respondent         hrs)
----------------------------------------------------------------------------------------------------------------
Contact by Mail.................................          17,610               1           10/60           2,935
Telephone Contact...............................           8,922               1           20/60           2,974
Parent Questionnaires and biologic sample.......           3,456               1          235/60          13,548
                                                                                        (3h 55m)
Caregiver Interview.............................           3,282               1           30/60           1,641
Clinic Visit (Child Development Evaluation,
 physical exam, and biosamples):
     Case...............................             810               1          355/60           4,793
                                                                                        (5h 55m)
     NIC................................           1,170               1          110/60           2,145
                                                                                        (1h 50m)
     Subcohort..........................           1,134               1          110/60           2,079
                                                                                        (1h 50m)
        TOTAL...................................  ..............  ..............  ..............          30,103
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    Dated: December 26, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. E6-22579 Filed 1-4-07; 8:45 am]
BILLING CODE 4163-18-P