[Federal Register Volume 71, Number 131 (Monday, July 10, 2006)]
[Notices]
[Pages 38889-38890]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E6-10728]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Toxicology Program (NTP); Liaison and Scientific Review 
Office; Meeting of the NTP Board of Scientific Counselors Technical 
Reports Review Subcommittee

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH).

ACTION: Meeting announcement and request for comments.

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SUMMARY: Pursuant to Public Law 92-463, notice is hereby given of a 
meeting of the NTP Board of Scientific Counselors Technical Reports 
Review Subcommittee (TRR Subcommittee). The primary agenda topic is the 
peer review of the findings and conclusions presented in five draft NTP 
Technical Reports of rodent toxicology and carcinogenicity studies in 
genetically modified mice conducted by the NTP (see Preliminary Agenda 
below). The TRR Subcommittee meeting is open to the public with time 
scheduled for oral public comment. The NTP also invites written 
comments on any draft technical report discussed at the meeting. The 
TRR Subcommittee deliberations on the draft technical reports will be 
reported to the NTP Board of Scientific Counselors (BSC) at a future 
date.

DATES: The TRR Subcommittee meeting will be held on August 28, 2006. 
All individuals who plan to attend are encouraged to register online by 
August 14, 2006, at the NTP Web site (http://ntp.niehs.nih.gov/ select 
``Calendar of Upcoming Events''). In order to facilitate planning for 
this meeting, persons wishing to make an oral presentation are asked to 
notify Dr. Barbara Shane via online registration, phone, or e-mail (see 
ADDRESSES below) by August 14, 2006, and if possible, to send a copy of 
the statement or talking points at that time. Written comments on the 
draft reports are also welcome and should also be received by August 
14, 2006, to enable

[[Page 38890]]

review by the TRR Subcommittee and NTP staff prior to the meeting. 
Persons needing special assistance, such as sign language 
interpretation or other reasonable accommodation in order to attend, 
should contact 919-541-2475 (voice), 919-541-4644 TTY (text telephone), 
through the Federal TTY Relay System at 800-877-8339, or by e-mail to 
[email protected]. Requests should be made at least 7 days in 
advance of the event.

ADDRESSES: The TRR Subcommittee meeting will be held in the Rodbell 
Auditorium, Rall Building at the NIEHS, 111 T. W. Alexander Drive, 
Research Triangle Park, NC 27709. A copy of the preliminary agenda, 
committee roster, and any additional information, when available, will 
be posted on the NTP Web site (http://ntp.niehs.nih.gov/ select 
``Calendar of Upcoming Events'') or provided upon request. Public 
comments and any other correspondence should be submitted to Dr. 
Barbara Shane, Executive Secretary for the NTP Board (NTP Liaison and 
Scientific Review Office, NIEHS, P.O. Box 12233, MD A3-01, Research 
Triangle Park, NC 27709; telephone: 919-541-4253, fax: 919-541-0295; or 
e-mail: [email protected]).

SUPPLEMENTARY INFORMATION:

Background

    The primary agenda topic is the peer review of the findings and 
conclusions of five draft NTP Technical Reports of rodent toxicology 
and carcinogenicity studies conducted by the NTP (see Preliminary 
Agenda below) in genetically modified mouse models. The TRR 
Subcommittee will also provide advice to the NTP on the utility of GMM 
models for cancer hazard identification.

Attendance and Registration

    The meeting is scheduled for August 28, 2006, from 8:30 a.m. to 
adjournment and is open to the public with attendance limited only by 
the space available. Individuals who plan to attend are encouraged to 
register online at the NTP website by August 14, 2006, at http://ntp.niehs.nih.gov/ select ``Advisory Boards and Committees'' to 
facilitate access to the NIEHS campus. Please note that a photo ID is 
required to access the NIEHS campus. The NTP is making plans to 
videocast the meeting through the Internet at http://www.niehs.nih.gov/external/video.htm.

Availability of Meeting Materials

    A copy of the preliminary agenda, committee roster, and any 
additional information, when available, will be posted on the NTP Web 
site (http://ntp.niehs.nih.gov/ select ``Calendar of Upcoming Events'') 
or may be requested in hardcopy from the Executive Secretary (see 
''ADDRESSES above). Following the meeting, summary minutes will be 
prepared and made available on the NTP Web site.

Request for Comments

    Public input at this meeting is invited and time is set aside for 
the presentation of public comments on any draft technical report. Each 
organization is allowed one time slot per agenda topic. At least 7 
minutes will be allotted to each speaker, and if time permits, may be 
extended to 10 minutes. Registration for oral comments will also be 
available on-site, although time allowed for presentation by on-site 
registrants may be less than that for pre-registered speakers and will 
be determined by the number of persons who register at the meeting.
    Persons registering to make oral comments are asked, if possible, 
to send a copy of their statement to Dr. Shane (see ADDRESSES above) by 
August 14, 2006, to enable review by the TRR Subcommittee and NTP staff 
prior to the meeting. Written statements can supplement and may expand 
the oral presentation. If registering on-site and reading from written 
text, please bring 40 copies of the statement for distribution to the 
TRR Subcommittee and NTP staff and to supplement the record. Written 
comments received in response to this notice will be posted on the NTP 
Web site. Persons submitting written comments should include their 
name, affiliation, mailing address, phone, fax, e-mail, and sponsoring 
organization (if any) with the document.

Background Information on the NTP Board of Scientific Counselors

    The NTP Board of Scientific Counselors (BSC) is a technical 
advisory body comprised of scientists from the public and private 
sectors who provide primary scientific oversight to the overall program 
and its centers. Specifically, the BSC advises the NTP on matters of 
scientific program content, both present and future, and conducts 
periodic review of the program for the purposes of determining and 
advising on the scientific merit of its activities and their overall 
scientific quality. The TRR Subcommittee is a standing subcommittee of 
the BSC. BSC members are selected from recognized authorities 
knowledgeable in fields such as toxicology, pharmacology, pathology, 
biochemistry, epidemiology, risk assessment, carcinogenesis, 
mutagenesis, molecular biology, behavioral toxicology and 
neurotoxicology, immunotoxicology, reproductive toxicology or 
teratology, and biostatistics. Its members are invited to serve 
overlapping terms of up to four years. BSC and TRR Subcommittee 
meetings are held annually or biannually.

    Dated: June 27, 2006.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Sciences 
and the National Toxicology Program.

Preliminary Agenda; National Toxicology Program (NTP) Board of 
Scientific Counselors Technical Reports Review Subcommittee Meeting; 
August 28, 2006; Rodbell Auditorium, Rall Building, National Institute 
of Environmental Health Sciences, 111 TW Alexander Drive, Research 
Triangle Park, NC

NTP Technical Reports (TR) Scheduled for Review

     GMM 07: Allyl Bromide (CASNR 106-95-6).
    [cir] Chemical intermediate in the manufacture of polymers, 
pharmaceuticals, and agricultural products.
     GMM 09: Dicyclohexylcarbodiimide (CASNR 538-75-0).
    [cir] Reagent in the chemical and pharmaceutical industries; 
stabilizing agent in elastomers, synthetic rubber, and other types of 
resins.
     GMM 08: Benzene (CASNR 71-43-2).
    [cir] Used in the manufacture of medicinal chemicals, dyes, oil, 
varnishes, and lacquers.
     GMM 13: Glycidol (CASNR 556-52-5).
    [cir] Stabilizer in the manufacture of vinyl polymers; additive for 
oil and synthetic hydraulic fluids.
     GMM 12: Phenolphthalein (CASNR 77-09-8).
    [cir] Laboratory reagent; cathartic drug in laxatives.
     The utility of genetically modified models for cancer 
hazard identification.

[FR Doc. E6-10728 Filed 7-7-06; 8:45 am]
BILLING CODE 4140-01-P