[Federal Register Volume 71, Number 58 (Monday, March 27, 2006)]
[Notices]
[Pages 15187-15188]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 06-2934]



[[Page 15187]]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[60Day-06-06AX]


Proposed Data Collections Submitted for Public Comment and 
Recommendations

    In compliance with the requirement of Section 3506(c)(2)(A) of the 
Paperwork Reduction Act of 1995 for opportunity for public comment on 
proposed data collection projects, the Centers for Disease Control and 
Prevention (CDC) will publish periodic summaries of proposed projects. 
To request more information on the proposed projects or to obtain a 
copy of the data collection plans and instruments, call 404-639-5960 
and send comments to Seleda Perryman, CDC Assistant Reports Clearance 
Officer, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail 
to [email protected].
    Comments are invited on: (a) Whether the proposed collection of 
information is necessary for the proper performance of the functions of 
the agency, including whether the information shall have practical 
utility; (b) the accuracy of the agency's estimate of the burden of the 
proposed collection of information; (c) ways to enhance the quality, 
utility, and clarity of the information to be collected; and (d) ways 
to minimize the burden of the collection of information on respondents, 
including through the use of automated collection techniques or other 
forms of information technology. Written comments should be received 
within 60 days of this notice.

Proposed Project

    Risk Perception, Worry, and Use of Ovarian Cancer Screening among 
Women at High, Elevated, and Average Risk of Ovarian Cancer--New--
National Center for Chronic Disease Prevention and Health Promotion 
(NCCDPHP), Centers for Disease Control and Prevention (CDC).

Background and Brief Description

    Accounting for an estimated 22,220 cases and 16,210 deaths in 2005, 
ovarian cancer is the most frequent cause of death from gynecologic 
malignancy in the United States. In over 80 percent of patients, 
ovarian cancer presents at a late clinical stage, affording a five-year 
survival rate of only 35 percent. For cases where ovarian cancer is 
identified in Stage I, however, the five-year survival rate exceeds 90 
percent.
    Identifying a woman's risk of ovarian cancer plays a large role in 
determining the appropriateness of having her undergo screening. It is 
only for women with a strong family history of ovarian and/or breast 
cancer or women with a hereditary genetic risk for ovarian cancer that 
the currently available screening modalities of CA 125 and transvaginal 
ultrasound are recommended.
    Statements from the scientific and medical community regarding 
recommendations for ovarian cancer screening play only a partial role 
in a woman's decision to undergo screening exams. Numerous 
psychological and sociological factors can affect this decision as 
well, including a woman's knowledge, attitudes, beliefs, and 
experiences. For instance, a woman's experience of cancer within her 
family or experience with a friend who has had cancer may influence a 
woman's screening decisions.
    The literature also notes that women with a family history of 
ovarian cancer report increased worry and high levels of perceived 
risk. A positive association has also been shown between screening 
behavior and family history. Recent studies indicate, however, that 
screening is not occurring in proportion to women's levels of risk. 
These findings underscore the need for a better understanding of how 
perceived risk of ovarian cancer may influence worry about cancer and 
ultimately screening behavior.
    To address these issues, the Division of Cancer Prevention and 
Control (DCPC), at the National Center for Chronic Disease Prevention 
and Health Promotion, Centers for Disease Control and Prevention, is 
conducting a study to examine the effects of family history of cancer, 
knowledge about ovarian cancer, worry and/or anxiety, and perceived 
risk of cancer on the likelihood of a woman undergoing screening for 
ovarian cancer. By also examining other psycho-social factors such as a 
woman's closeness to a relative or friend with cancer, coping style, 
cancer worry, use of other cancer screening tests, social support, and 
provider's recommendations, the study will elucidate the causal pathway 
leading from actual risk (as measured by family history) through 
perceived risk to intent to undergo screening and actual screening 
behavior.
    The proposed study will consist of two tasks:
    Task 1, a brief eligibility screener (5 minutes) preceding a 
baseline survey administered through a computer-assisted telephone 
interview (CATI) program. Approximately 2000 women will be asked a 
series of questions over a 35-minute time period. Questions will cover 
key variables related to ovarian cancer screening including coping, 
anxiety, perceived risk, worry, personal cancer history, family cancer 
history, closeness with family or friends who have had cancer, 
screening behavior, and knowledge of ovarian cancer.
    Task 2, a follow-up questionnaire will be administered, also using 
a CATI program, to approximately 1800 of the women included in the 
baseline questionnaire. Each of the women will be contacted one year 
after they complete the baseline survey. The researchers anticipate a 
10 percent attrition of the sample between baseline and follow-up. In 
the follow-up, women will be asked a series of questions over a 15-
minute time period. The purpose of this data collection effort is to 
determine if risk perception has changed and to ask about screening for 
ovarian cancer, since the baseline questionnaire was administered. All 
data will be collected over a three-year time period. There are no 
costs to respondents except their time to participate in the survey.

                                        Estimated Annualized Burden Table
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                                                                    No. of      Average  burden
                 Respondents                       No. of       Responses per    per  response     Total burden
                                                Respondents       respondent       (in hrs.)        (in hours)
----------------------------------------------------------------------------------------------------------------
Telephone Screener..........................            10667                1             5/60              889
Baseline Survey (women 30 or older).........              667                1            35/60              389
Follow-up Survey (completed Baseline Survey)              600                1            15/60              150
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    Total...................................  ...............  ...............  ...............             1428
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[[Page 15188]]

    Dated: March 20, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. 06-2934 Filed 3-24-06; 8:45 am]
BILLING CODE 4163-18-P