[Federal Register Volume 70, Number 234 (Wednesday, December 7, 2005)]
[Notices]
[Pages 72840-72842]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E5-6971]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[ATSDR-217]


Notice of the Revised Priority List of Hazardous Substances That 
Will Be the Subject of Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), U.S. 
Department of Health and Human Services (HHS).

ACTION: Notice.

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SUMMARY: The Comprehensive Environmental Response, Compensation, and 
Liability Act (CERCLA or Superfund), as amended by the Superfund 
Amendments and Reauthorization Act (SARA), requires that ATSDR and the 
Environmental Protection Agency (EPA) revise the Priority List of 
Hazardous Substances. This list includes substances most commonly found 
at facilities on the CERCLA National Priorities List (NPL) which have 
been determined to be of greatest concern to public health at or around 
these NPL hazardous waste sites. This announcement provides notice that 
the agencies have developed and are making available a revised CERCLA 
Priority List of 275 Hazardous Substances, based on the most recent 
information available. Each substance on the priority list is a 
candidate to become the subject of a toxicological profile prepared by 
ATSDR and

[[Page 72841]]

subsequently a candidate for the identification of priority data needs.
    In addition to the Priority List of Hazardous Substances, ATSDR has 
developed a Completed Exposure Pathway Site Count Report. This report 
lists the number of sites or events with ATSDR activities where a 
substance has been found in a completed exposure pathway (CEP). This 
report is included in the Support Document of the Priority List.

ADDRESSES: Requests for a printed copy of the report, the 2005 CERCLA 
Priority List of Hazardous Substances That Will Be The Subject of 
Toxicological Profiles and Support Document, including the CEP report, 
should bear the docket control number ATSDR-217, and should be 
submitted to: Ms. Olga Dawkins, Division of Toxicology and 
Environmental Medicine, Mail Stop F-32, 1600 Clifton Road, NE., 
Atlanta, GA 30333. Requests must be in writing.
    Electronic Availability: The 2005 Priority List of Hazardous 
Substances and Support Document will be posted on ATSDR's Web site 
located at http://www.atsdr.cdc.gov/clist.html. The CEP Report will 
also be posted at http://www.atsdr.cdc.gov/cep.html.
    This is an informational notice only, and comments are not being 
solicited at this time. However, any comments received will be 
considered for inclusion in the next revision of the list and placed in 
a publicly accessible docket; therefore, please do not submit 
confidential business or other confidential information.

FOR FURTHER INFORMATION CONTACT: ATSDR, Division of Toxicology and 
Environmental Medicine, 1600 Clifton Road, NE., Mail Stop F-32, 
Atlanta, GA 30333, telephone 888-422-8737.

SUPPLEMENTARY INFORMATION: CERCLA establishes certain requirements for 
ATSDR and EPA with regard to hazardous substances that are most 
commonly found at facilities on the CERCLA NPL. Section 104(i)(2) of 
CERCLA, as amended [42 U.S.C. 9604(i)(2)], required that the two 
agencies prepare a list, in order of priority, of at least 100 
hazardous substances that are most commonly found at facilities on the 
NPL and which, in their sole discretion, have been determined to pose 
the most significant potential threat to human health (see 52 FR 12866, 
April 17, 1987). CERCLA also required the agencies to revise the 
priority list to include 100 or more additional hazardous substances 
(see 53 FR 41280, October 20, 1988), and to include at least 25 
additional hazardous substances in each of the three successive years 
following the 1988 revision (see 54 FR 43619, October 26, 1989; 55 FR 
42067, October 17, 1990; 56 FR 52166, October 17, 1991). CERCLA also 
requires that ATSDR and EPA shall, at least annually thereafter, revise 
the list to include additional hazardous substances that have been 
determined to pose the most significant potential threat to human 
health. In 1995, the agencies altered the publication schedule of the 
priority list by moving to a 2-year publication schedule, reflecting 
the stability of this listing activity (60 FR 16478, March 30, 1995). 
As a result, the priority list is now on a 2-year publication schedule 
with a yearly informal review and revision. Each substance on the 
CERCLA Priority List of Hazardous Substances is a candidate to become 
the subject of a toxicological profile prepared by ATSDR and 
subsequently a candidate for the identification of priority data needs.
    The initial priority lists of hazardous substances (1987-1990) were 
based on the most comprehensive and relevant information available when 
the lists were developed. More comprehensive sources of information on 
the frequency of occurrence and the potential for human exposure to 
substances at NPL sites became available for use in the 1991 priority 
list with the development of ATSDR's HazDat database. Utilizing this 
database, a revised approach and algorithm for ranking substances was 
developed in 1991, and a notice announcing the intention of ATSDR and 
EPA to revise and rerank the Priority List of Hazardous Substances was 
published on June 27, 1991 (56 FR 29485). The subsequent 1991 Priority 
List and revised approach used for its compilation was summarized in 
the ``Revised Priority List of Hazardous Substances'' Federal Register 
notice published October 17, 1991 (56 FR 52166). The same approach and 
the same basic algorithm have been used in all subsequent activities, 
including the 2005 listing activity. The algorithm used in ranking 
hazardous substances on the priority list consists of three criteria, 
which are combined to result in the total score. The three criteria 
are: Frequency of occurrence at NPL sites; toxicity; and potential for 
human exposure.
    Since HazDat is a dynamic database with ongoing data collection, 
additional information from the HazDat database became available for 
the 2005 listing activity. This additional information has been entered 
into HazDat since the development of the 2003 Priority List of 
Hazardous Substances. The site-specific information from HazDat that is 
used in the listing activity has been collected from ATSDR public 
health assessments and from site file data packages that are used to 
develop these public health assessments. The new information may 
include more recent NPL frequency of occurrence data, additional 
concentration data, and more information on exposure to substances at 
NPL sites. With these additional data, 10 substances have been replaced 
on the list of 275 substances since the 2003 publication. Of the 10 
replacement substances, 2 are new candidate substances, and 8 are 
substances that were previously under consideration. These replacement 
substances and changes in the order of substances appearing on the 
CERCLA Priority List of Hazardous Substances will be reflected in the 
program activities that rely on the list for future direction.
    The 2005 Priority List of Hazardous Substances includes 275 
substances that have been determined to be of greatest concern to 
public health based on the criteria of CERCLA section 104(i)(2) [42 
U.S.C. 9604(i)(2)]. A total of 861 candidate substances have been 
analyzed and ranked with the current algorithm. Of these candidates, 
the 275 substances on the priority list may become the subject of 
toxicological profiles in the future. The top 25 substances on the 2005 
Priority List of Hazardous Substances are listed below.

------------------------------------------------------------------------
               Rank                            Substance name
------------------------------------------------------------------------
1................................  Arsenic
2................................  Lead
3................................  Mercury
4................................  Vinyl Chloride
5................................  Polychlorinated Biphenyls
6................................  Benzene
7................................  Polycyclic Aromatic Hydrocarbons
8................................  Cadmium
9................................  Benzo (A) Pyrene
10...............................  Benzo (B) Fluoranthene
11...............................  Chloroform
12...............................  Ddt, P,P'-
13...............................  Aroclor 1254
14...............................  Aroclor 1260
15...............................  Dibenzon (A,H) Anthracene
16...............................  Trichloroethylene
17...............................  Dieldrin
18...............................  Chromium, Hexavalent
19...............................  Phosphorus, White
20...............................  Dde, P,P'-
21...............................  Chlordane
22...............................  Hexachlorobutadiene
23...............................  Coal Tar Creosote
24...............................  Ddd, P',P'-
25...............................  Aldrin
------------------------------------------------------------------------

    ATSDR intends to publish the next revised list of hazardous 
substances in two years, with an informal review and revision performed 
in one year. These revisions will reflect changes and improvements in 
data collection and

[[Page 72842]]

availability. Additional information on the existing methodology used 
in the development of the CERCLA Priority List of Hazardous Substances 
can be found in the Support Document to the List and in the Federal 
Register notices mentioned above.
    In addition to the revised priority list, ATSDR is also releasing a 
Completed Exposure Pathway Site Count Report. A completed exposure 
pathway (CEP) is an exposure pathway that links a contaminant source to 
a receptor population. The CEP ranking is very similar to a sub-
component of the potential-for-human-exposure component of the listing 
algorithm. The CEP ranking is based on a site frequency count, and thus 
lists the number of sites at which a substance has been found in a CEP. 
ATSDR's HazDat database contains this information which is derived from 
ATSDR public health assessments and health consultations. Because 
exposure to hazardous substances is of significant concern, ATSDR is 
publishing this CEP report along with the CERCLA Priority List of 
Hazardous Substances. Since this CEP report focuses on documented 
exposure, it provides an important prioritization based on substances 
to which people are exposed.
    The substances on the CEP report are similar to the substances on 
the CERCLA Priority List of Hazardous Substances. However, there are 
some substances that are on the CEP report because they are frequently 
found in completed exposure pathways, but are not on the CERCLA 
Priority List because they have a very low toxicity (e.g., sodium). 
Since the CERCLA Priority List incorporates three different components 
(toxicity, frequency of occurrence, and potential for human exposure) 
to determine its priority substances, substances with very low toxicity 
are not on the CERCLA Priority List and consequently are not the 
subject of toxicological profiles. In addition, since the Priority List 
is mandated by CERCLA, it only uses data from sites on the CERCLA 
National Priorities List, whereas the CEP report uses data from all 
sites with ATSDR activities that have a CEP. Of the 100 substances on 
the CEP report, the 25 substances found at the most number of sites in 
a CEP are presented below.

------------------------------------------------------------------------
                                                             Number of
                                                            sites with
                                                          substance in a
                     Substance name                             CEP
                                                         ---------------
                                                            All     NPL
                                                           sites   sites
------------------------------------------------------------------------
Lead....................................................     431     267
Trichloroethylene.......................................     363     286
Arsenic.................................................     341     208
Tetrachloroethylene.....................................     280     207
Benzene.................................................     210     137
Cadmium.................................................     207     136
Volatile Organic Compounds, Unspecified.................     193     132
Chromium................................................     193     129
Polychlorinated Biphenyls...............................     177     116
Mercury.................................................     167      93
Manganese...............................................     164      95
Zinc....................................................     158      95
Copper..................................................     143      83
1,1,1-Trichloroethane...................................     135     110
Chloroform..............................................     124      92
Benzo(A)Pyrene..........................................     122      58
1,1-Dichloroethene......................................     117      96
Polycyclic Aromatic Hydrocarbons........................     117      79
Nickel..................................................     112      70
Methylene Chloride......................................     111      73
Toluene.................................................     111      68
Antimony................................................     108      69
Vinyl Chloride..........................................     103      84
Barium..................................................     102      56
1,2-Dichloroethane......................................      96      77
------------------------------------------------------------------------
Note: Sorted by the All Sites column.
All Sites = all sites with ATSDR activities that have a CEP; NPL.
Sites = current and former sites on the National Priorities List, as
  mandated.


    Dated: November 29, 2005.
Ken Rose,
Acting Director, Office of Policy, Planning and Evaluation, National 
Center for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. E5-6971 Filed 12-6-05; 8:45 am]
BILLING CODE 4163-70-P