[Federal Register Volume 69, Number 162 (Monday, August 23, 2004)]
[Notices]
[Pages 51847-51851]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 04-19225]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention


ADAPT: Adopting and Demonstrating the Adaptation of Prevention 
Techniques

    Announcement Type: Competitive Supplement.
    Funding Opportunity Number: PA 04064 (Supplemental).
    Catalog of Federal Domestic Assistance Number: 93.944.
    Dates: Letter of Intent Deadline: None.
    Application Deadline: September 22, 2004.

I. Funding Opportunity Description

    Authority: This program is authorized under sections 301 and 317(k) 
of the Public Health Service Act, (42 U.S.C. 241 and 247b(k)), as 
amended.

Purpose

    The purpose of this program is to improve understanding of the 
processes needed for adapting evidence-based interventions to fit new 
conditions or populations and to pilot CDC-developed draft guidance for 
adaptation.
    The ADAPT project responds to concerns from the field that existing 
interventions do not address the HIV prevention needs of their specific 
population. This project seeks to develop guidance for agencies to 
engage in evidence-based adaptation of interventions previously shown 
to be effective in research settings for use in real world 
applications. If data from this project is published, it will be 
published as case studies and not as generalizable research data.

Activities

    Supplemental funds are intended to support 3-5 eligible grantees 
that are currently participating in Community-Based Organizations (CBO) 
PA 04064. The funds will support additional activities that involve 
adapting an HIV prevention intervention listed in the Procedural 
Guidance for Selected Strategies and Interventions for Community-Based 
Organizations Funded Under Program Announcement 04064 (Procedural 
Guidance) for use in an HIV seropositive population of men of color who 
have sex with other men (MSM of color). CDC is especially interested in 
supporting projects that use the Many Men, Many Voices (MMMV) 
intervention listed in the Procedural Guidance. Contingent upon the 
quality of proposals, CDC anticipates that at least one of the 
applicants funded under the ADAPT supplement will adapt and implement 
MMMV. However, applicants are not limited to this particular 
intervention and may propose work using any one of the other 
interventions listed in the Procedural Guidance. Funded applicants will 
further evaluate the intervention they select to adapt. Preference will 
be given to those applicants that have limited or no previous 
experience with the adaptation and implementation of the intervention 
they were funded to implement under CBO PA 04064. Funded applicants 
will be required to conduct two evaluation components for this award: 
(1) To monitor and evaluate the adaptation process; and (2) to monitor 
and evaluate the intervention.
    In a cooperative agreement, CDC staff is substantially involved in 
the program activities, above and beyond routine grant monitoring.
    CDC Activities for this program are as follows:
     CDC will provide to funded applicants the draft adaptation 
guidance developed by CDC with input from internal and external 
researchers, HIV prevention intervention implementers, and community 
advocates.
     CDC will provide process and outcome indicators and work 
with funded applicants in the evaluation processes for this award. The 
evaluation methods could include, but are not limited to: timelines; 
qualitative summaries; focus group summaries; unstructured key 
informant interviews; case studies; checklists; progress reports; and 
perhaps information on costs. Note that evaluation activities will 
include unstructured interviews with key stakeholders before and after 
the implementation of the adapted intervention(s). Outcome measures 
could include, but are not limited to, behavioral outcomes such as 
condom use or frequency of unprotected sex, or biological outcomes such 
as sexually transmitted disease (STD) incidence as collected with the 
Program Evaluation and Monitoring System (PEMS).

II. Award Information

    Type of Award: Cooperative Agreement. CDC involvement in this 
program is listed in the Activities Section above.
    Fiscal Year Funds: 2004--2006.
    Approximate Total Funding: The estimated total cost is $5,000,000 
with approximately $2,000,000 awarded during the first fiscal year.
    Approximate Number of Awards: 3-5.
    Approximate Average Award: $575,000 (This amount is for the first 
12-month budget period, and includes both direct and indirect costs).
    Floor of Award Range: $200,000.
    Anticipated Award Date: September 1, 2004.
    Budget Period Length: 12 months.
    Project Period Length: 2 years.
    Throughout the project period, CDC's commitment to continuation of 
awards will be conditioned on the availability of funds, evidence of 
satisfactory progress by the recipient (as documented in required 
reports), and the determination that continued funding is in the best 
interest of the Federal Government.

III. Eligibility Information

III.1. Eligible applicants

    Applications may only be submitted by grantees currently funded 
under CBO PA 04064 who are eligible to apply for supplemental funding.

III.2. Cost Sharing or Matching

    Matching funds are not required for this program.

III.3. Other

    If your application is incomplete or non-responsive to the 
requirements listed in this section, it will not be entered into the 
review process. You will be notified that your application did not meet 
submission requirements.

[[Page 51848]]

    Eligibility Criteria:
    Eligibility criteria are briefly outlined below. When writing the 
proposal narrative, applicants should refer to the scoring criteria 
section for additional details.
    a. Only grantees currently funded under CBO PA 04064 are eligible 
to apply for supplemental funding.
    b. The applicant must demonstrate access to an adequate population 
of HIV seropositive MSM of color who are currently not receiving other 
prevention interventions. The applicant must demonstrate ability to 
obtain a sample size comparable to that found in the original research 
study.
    c. The applicant must demonstrate adequate personnel for conducting 
ADAPT activities in addition to CBO PA 04064 activities. Personnel 
assigned to ADAPT activities should include, but are not limited to, an 
onsite, full-time person with expertise in development and adaptation 
of interventions based on behavioral theory (adaptation specialist) who 
works collaboratively with the CBO PA 04064 project coordinator to take 
the lead on ADAPT activities; a full-time data manager; a full-time 
data entry position; and a part-time administrator.
    d. The applicant must demonstrate ability to accomplish ADAPT 
activities within a 2-year project period.
    e. The applicant must adequately address all sections of the 
description of work in the narrative of the proposal.
    (1) Approach. The applicant must demonstrate that plans for 
adapting, implementing, and monitoring and evaluating the selected 
intervention are adequately developed, well-integrated, and appropriate 
to the aims of the project.
    (2) Significance. The applicant must demonstrate understanding of 
the intent and purpose of ADAPT.
    (3) Personnel. The applicant must demonstrate adequate personnel 
for conducting ADAPT activities in addition to CBO PA 04064 activities 
(i.e., adaptation specialist, data manager, data entry, part-time 
administrator).
    (4) Environment. The applicant should demonstrate how levels of 
administrative support, community involvement, facilities, and other 
resources at the CBO in which the work will be done contribute to the 
probability of success.


    Note: Title 2 of the United States Code Section 1611 states that 
an organization described in section 501(c)(4) of the Internal 
Revenue Code that engages in lobbying activities is not eligible to 
receive Federal funds constituting an award, grant, or loan.

IV. Application and Submission Information

IV.1. Address To Request Application Package

    To apply for this funding opportunity use application form PHS 
5161. Application forms and instructions are available on the CDC web 
site, at the following Internet address: http://www.cdc.gov/od/pgo/forminfo.htm.
    If you do not have access to the Internet, or if you have 
difficulty accessing the forms on-line, you may contact the CDC 
Procurement and Grants Office Technical Information Management Section 
(PGO-TIM) staff at: 770-488-2700. Application forms can be mailed to 
you.

IV.2. Content and Form of Submission

    Application: You must submit a project narrative with your 
application forms. The narrative must be submitted in the following 
format:
     Maximum number of pages: 25 (not including budget 
justification and appendices). If your narrative exceeds the page 
limit, only the first pages which are within the page limit will be 
reviewed.
     Font size: 12 point unreduced.
     Double spaced.
     Paper size: 8.5 by 11 inches.
     Page margin size: One inch.
     Printed only on one side of page.
     Held together only by rubber bands or metal clips; not 
bound in any other way.
     MS WORD format.
     Cover page--the program announcement number and title.
     Table of contents--with the major sections and page 
numbering including each attachment.
     Consecutive page numbering throughout the document, 
including the attachments.

[cir] Beginning with the first page of text, number all pages clearly 
and sequentially, including each page in the appendices.
[cir] Replace double-sided article reprints with a one-sided copy.

    Your narrative should address activities to be conducted over the 
entire project period, and must include the following items in the 
order listed below.
A. Specific Aims
    Applications must include a one-page, double-spaced executive 
summary as a cover page.

 Maximum number of pages: 1.
 Font size: 12-point unreduced.
 Double spaced.
 Paper size: 8.5 by 11 inches.
 Page margin size: One inch.
 Printed only on one side of page.
 Written in plain language, avoid jargon.

    A complete table of contents to the application and its appendices, 
and text addressing each required element is required.
B. Background and Significance
     An explanation of how the applicant identified, gained 
access to, and assessed the prevention needs of the selected target 
population.
     The rationale for selection of proposed target population 
and intervention match.
C. Preliminary Studies/Progress Report
     Provide evidence of the applicant's previous experience in 
conducting process evaluation, quality assurance, and evaluation.
     An outline of personnel roles and responsibilities related 
to conducting ADAPT project activities.
    The remaining sections of the proposal narrative should correspond 
with sections of the scoring criteria. The applicant must adequately 
address all relevant items in each section of the scoring criteria.
D. Approach
    The applicant must demonstrate that plans for adapting, 
implementing, and monitoring and evaluating the selected intervention 
are adequately developed, well-integrated, and appropriate to the aims 
of the project.
    The applicant must submit a copy of their CBO PA 04064 application 
packet and award letter.
E. Significance
    The applicant must demonstrate understanding of the intent and 
purpose of ADAPT.
F. Personnel
    The applicant must demonstrate adequate personnel for conducting 
ADAPT activities in addition to CBO PA 04064 activities (i.e., 
adaptation specialist, data manager, data entry, part-time 
administrator).
G. Environment
    The applicant should demonstrate how levels of administrative 
support, community involvement, facilities, and other resources at the 
CBO in which the work will be done contribute to the probability of 
success.

[[Page 51849]]

H. Budget and Justification (Not Included in Page Limit)
I. Additional Information
    Additional information may be included in the application 
appendices. The appendices will not be counted toward the narrative 
page limit. This additional information includes: Curriculum Vitae, 
Resumes, Organizational Charts, and Letters of Support. Applications 
must include Letters of Support (LOS) from institutions that will play 
a role in conducting ADAPT activities. Each LOS should include a 
description of the past relationship with the applicant and the role(s) 
the local partner will play in conducting ADAPT activities (e.g., 
accessing the target population, implementing the selected 
intervention, staff involved). The LOS must be written in the following 
format:

 Maximum number of pages: 1.
 Font size: 12-point unreduced.
 Double spaced.
 Paper size: 8.5 by 11 inches.
 Page margin size: One inch.
 Printed only on one side of page.
 Written in plain language, avoid jargon.

    You are required to have a Dun and Bradstreet Data Universal 
Numbering System (DUNS) number to apply for a grant or cooperative 
agreement from the Federal government. The DUNS number is a nine-digit 
identification number, which uniquely identifies business entities. 
Obtaining a DUNS number is easy and there is no charge. To obtain a 
DUNS number, access http://www.dunandbradstreet.com or call 1-866-705-
5711.
    For more information, see the CDC Web site at: http://www.cdc.gov/od/pgo/funding/pubcommt.htm If your application form does not have a 
DUNS number field, please write your DUNS number at the top of the 
first page of your application, and/or include your DUNS number in your 
application cover letter.
    Additional requirements that may require you to submit additional 
documentation with your application are listed in section ``VI.2. 
Administrative and National Policy Requirements.''

IV.3. Submission Dates and Times

    Application Deadline Date: September 22, 2004.
    Explanation of Deadline: Applications must be received in the CDC 
Procurement and Grants Office by 4 p.m. Eastern Time on the deadline 
date. If you send your application by the United States Postal Service 
or commercial delivery service, you must ensure that the carrier will 
be able to guarantee delivery of the application by the closing date 
and time. If CDC receives your application after closing due to: (1) 
Carrier error, when the carrier accepted the package with a guarantee 
for delivery by the closing date and time, or (2) significant weather 
delays or natural disasters, you will be given the opportunity to 
submit documentation of the carrier's guarantee. If the documentation 
verifies a carrier problem, CDC will consider the application as having 
been received by the deadline.
    This announcement is the definitive guide on application submission 
address and deadline. It supersedes information provided in the 
application instructions. If your application does not meet the 
deadline above, it will not be eligible for review, and will be 
discarded. You will be notified that your application did not meet the 
submission requirements.
    CDC will not notify you upon receipt of your application. If you 
have a question about the receipt of your application, first contact 
your courier. If you still have a question, contact the PGO-TIM staff 
at: 770-488-2700. Before calling, please wait two to three days after 
the application deadline. This will allow time for applications to be 
processed and logged.

IV.4. Intergovernmental Review of Applications

    Executive Order 12372 does not apply to this program.

IV.5. Funding Restrictions

    Restrictions, which must be taken into account while writing your 
budget, are as follows:
     No furniture should be purchased with ADAPT funds.
     No rent should be paid for with ADAPT funds unless the 
amount is prorated to cover space occupied solely by ADAPT staff.
     Travel costs must conform to government rates.
     No construction should be paid for with ADAPT funds.
     Awards will not allow reimbursement of pre-award costs.
    If you are requesting indirect costs in your budget, you must 
include a copy of your indirect cost rate agreement. If your indirect 
cost rate is a provisional rate, the agreement should be less than 12 
months of age.
    Guidance for completing your budget can be found on the CDC Web 
site, at the following Internet address: http://www.cdc.gov/od/pgo/funding/budgetguide.htm.

IV.6. Other Submission Requirements

    Application Submission Address: Submit the original and two hard 
copies of your application by mail or express delivery service to: 
Technical Information Management-PA 04064, CDC Procurement and 
Grants Office,2920 Brandywine Road, Atlanta, GA 30341.
    Applications may not be submitted electronically at this time.

V. Application Review Information

V.1. Criteria

    You are required to provide measures of effectiveness that will 
demonstrate the accomplishment of the various identified objectives of 
the cooperative agreement. Measures of effectiveness must relate to the 
performance goals stated in the ``Purpose'' section of this 
announcement. Measures must be objective and quantitative, and must 
measure the intended outcome. These measures of effectiveness must be 
submitted with the application and will be an element of evaluation.
    The reviewers will consider each of the following criteria in 
assigning the overall score, weighting them as appropriate for each 
proposal. Your application will be evaluated against the scoring 
criteria as follows:
A. Approach (35 percent)
     Has applicant included a brief abstract summarizing their 
ADAPT project proposal?
     Has the applicant submitted a copy of their CBO PA 04064 
application packet and award letter?
     Are the plans for adapting, implementing, and monitoring 
and evaluating the selected intervention adequately developed, well-
integrated, and appropriate to the aims of the project?
     Has the applicant provided strong evidence of experience 
with process evaluation, quality assurance, and evaluation with other 
related projects?
     Has the applicant provided a quality assurance plan (QASP) 
that addresses all phases of adaptation, implementation, and monitoring 
and evaluation and includes proposed process and outcome measures and 
personnel responsible for ensuring quality?
     Has the applicant included a timeline including dates that 
tasks are to be implemented and completed; costs; development of 
materials (e.g., adapted training curriculum, evaluation tools, and 
checklists); and quarterly progress report dates?
     Does the applicant acknowledge potential problem areas and 
consider

[[Page 51850]]

alternative tactics (i.e., recruitment, competing priorities, staffing, 
and coordinating ADAPT & CBO PA 04064 activities and PEMS)?
     Has the applicant included how they identified, gained 
access to, and rapidly assessed the target population (e.g., via 
community planning groups [CPGs], community advisory boards [CABs], and 
focus groups)?
     Has the applicant demonstrated access to an adequate 
population of HIV seropositive MSM of color who are currently not 
receiving other prevention interventions? Can applicant obtain a sample 
size comparable to that found in the original research study of the 
chosen intervention?
     Is the target population of HIV seropositive MSM of color 
population not targeted by the original intervention?
     Has the applicant provided a plan for training staff on 
the implementation of the adapted intervention?
     Has the applicant provided a plan and protocol for timely 
adaptation, implementation, and evaluation of the intervention?
     Does the applicant's proposed budget for ADAPT activities 
include, but is not limited to, personnel (i.e., adaptation specialist, 
data manager, data entry, part-time administrator), travel (2 trips to 
Atlanta for the adaptation specialist), and supplies?
B. Significance (30 Percent)
     Does the applicant demonstrate understanding of the intent 
and purpose of ADAPT?
     Is the target population HIV seropositive MSM of color?
     Is the selection of the target population justified in 
terms of risk, service level, and HIV incidence?
     Did the applicant provide the rationale for 
appropriateness of agency, target population, and intervention match?
     Are the agency, target population, and intervention 
realistically matched in terms of agency resources and experience, 
behavioral determinants, and risk behaviors of the target population, 
and maintaining fidelity to the core elements of the intervention?
     Did the applicant document adequate capacity to implement 
the chosen intervention?
C. Personnel (20 Percent)
     Has the applicant demonstrated adequate personnel for 
conducting ADAPT activities in addition to CBO PA 04064 activities 
(i.e., adaptation specialist, data manager, data entry, part-time 
administrator)?
     Does the applicant demonstrate adequate capacity and 
skills necessary to identify at-risk populations, use local data, and 
collaborate with partners (if applicable)?
     Is the applicant staff appropriately trained and well 
suited to carry out this work?
     Is the work proposed appropriate to the experience level 
of the applicant staff?
     Does the applicant demonstrate previous experience in 
managing HIV prevention efforts?
D. Environment (15 percent)
     Are the levels of administrative support, community 
involvement, facilities, and other resources at the CBO in which the 
work will be done sufficient to contribute to a high probability of 
success?
     Has the applicant demonstrated how they established and 
maintain collaboration with local partners, if relevant (e.g., local 
health departments, universities, CBOs, ASOs, and research entities)?
     Has the applicant demonstrated adequate support for ADAPT 
activities (e.g., commitment of resources such as personnel and time; 
commitment from management; commitment from community partners).
     Has the applicant provided a plan for separate budgeting 
of ADAPT and CBO PA 04064 funds?

V.2. Review and Selection Process

    Applications will be reviewed for completeness by the Procurement 
and Grants Office (PGO) staff, and for responsiveness by National 
Center for HIV/AIDS, STD, TB Prevention. Incomplete applications and 
applications that are non-responsive to the eligibility criteria will 
not advance through the review process. Applicants will be notified 
that their application did not meet submission requirements.
    An objective review panel will evaluate complete and responsive 
applications according to the criteria listed in the ``V.1. Criteria'' 
section above.
    In addition, the following factors may affect the funding decision:

Executive Summary
Letters of Support
Selected Intervention. CDC is especially interested in supporting 
projects that use the MMMV intervention listed in the Procedural 
Guidance. Contingent upon the quality of proposals, CDC anticipates 
that at least one of the applicants funded under the ADAPT supplement 
will adapt and implement MMMV. However, applicants are not limited to 
this particular intervention and may propose work using any one of the 
other interventions listed in the Procedural Guidance.

V.3. Anticipated Announcement and Award Dates

    Award date: September 1, 2004.

VI. Award Administration Information

VI.1. Award Notices

    Successful applicants will receive a Notice of Grant Award (NGA) 
from the CDC Procurement and Grants Office. The NGA shall be the only 
binding, authorizing document between the recipient and CDC. The NGA 
will be signed by an authorized Grants Management Officer, and mailed 
to the recipient fiscal officer identified in the application.
    Unsuccessful applicants will receive notification of the results of 
the application review by mail.

VI.2. Administrative and National Policy Requirements

    45 CFR Part 74 and Part 92
    For more information on the Code of Federal Regulations, see the 
National Archives and Records Administration at the following Internet 
address: http://www.access.gpo.gov/nara/cfr/cfr-table-search.html.
    The following additional requirements apply to this project:

 AR-4 HIV/AIDS Confidentiality Provisions
 AR-5 HIV Program Review Panel Requirements
 AR-7 Executive Order 12372
 AR-8 Public Health System Reporting Requirements
 AR-9 Paperwork Reduction Act Requirements
 AR-10 Smoke-Free Workplace Requirements
 AR-11 Healthy People 2010
 AR-12 Lobbying Restrictions
 AR-14 Accounting System Requirements
 AR-15 Proof of Non-Profit Status

    Additional information on these requirements can be found on the 
CDC web site at the following Internet address: http://www.cdc.gov/od/pgo/funding/ARs.htm.

VI.3. Reporting Requirements

    You must provide CDC with an original, plus two hard copies of the 
following reports:
    1. Interim progress report, no less than 90 days before the end of 
the budget period. The progress report will serve as your non-competing 
continuation application, and must contain the following elements:
    a. Current Budget Period Activities Objectives.

[[Page 51851]]

    b. Current Budget Period Financial Progress.
    c. New Budget Period Program Proposed Activity Objectives.
    d. Budget.
    e. Additional Requested Information.
    f. Measures of Effectiveness.
    2. Financial status report no more than 90 days after the end of 
the budget period.
    3. Final financial and performance reports, no more than 90 days 
after the end of the project period.
    These reports must be mailed to the Grants Management or Contract 
Specialist listed in the ``Agency Contacts'' section of this 
announcement.

VII. Agency Contacts

    For general questions about this announcement, contact:

Technical Information Management Section, CDC Procurement and Grants 
Office, 2920 Brandywine Road, Atlanta, GA 30341, Telephone: 770-488-
2700.

    For program technical assistance, contact:

Vel McKleroy, Extramural Co-Project Officer, Centers for Disease 
Control and Prevention, 1600 Clifton Road, Mailstop E-37, Atlanta 
Georgia, 30333, Telephone: (404) 639-2982, E-mail: [email protected].
     OR
Jennifer Galbraith, Extramural Co-Project Officer, Centers for Disease 
Control and Prevention, 1600 Clifton Road, Mailstop E-37, Atlanta 
Georgia, 30333, Telephone: (404) 639-8649, E-mail: [email protected].

    For financial, grants management, or budget assistance, contact:

Brenda Hayes, Grants Management Specialist, CDC Procurement and Grants 
Office, 2920 Brandywine Road, Atlanta, GA 30341, Telephone: 770-488-
2741, E-mail: [email protected].

    Dated: August 17, 2004.
William P. Nichols,
Acting Director, Procurement and Grants Office, Centers for Disease 
Control and Prevention.
[FR Doc. 04-19225 Filed 8-20-04; 8:45 am]
BILLING CODE 4163-70-P