[Federal Register Volume 69, Number 79 (Friday, April 23, 2004)]
[Notices]
[Pages 22052-22053]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 04-9234]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30Day-42-04]


Proposed Data Collections Submitted for Public Comment and 
Recommendations

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Officer at (404) 498-1210. Send written 
comments to CDC, Desk Officer, Human Resources and Housing Branch, New 
Executive Office Building, Room 10235, Washington, DC 20503 or by fax 
to (202) 395-6974. Written comments should be received within 30 days 
of this notice.
    Proposed Project: Delayed Symptoms Associated with the Convalescent 
Period of a Dengue Infection--New--National Center for Infectious 
Diseases (NCID), Centers for Disease Control and Prevention (CDC). 
Dengue is a vector-borne febrile disease of the tropics transmitted 
most often by the mosquito Aedes aegypti. Symptoms of the acute disease 
include fever, headache, rash, retro-orbital pain, myalgias, 
arthralgias, vomiting, abdominal pain and hemorrhagic manifestations.
    Many symptoms are mentioned in the medical literature as associated 
with the convalescent period (three-eight weeks) after dengue 
infection, including depression, dementia, loss of sensation, paralysis 
of lower and upper extremities and larynx, epilepsy, tremors, manic 
psychosis, amnesia, loss of visual acuity, hair loss, and peeling of 
skin. No epidemiologic study has been conducted to define the timing, 
frequency, and risk factors for these symptoms. The objective of this 
study is to examine the incidence and characteristics of mental health 
disorders and other delayed complications associated with dengue 
infection and convalescence. The study will be conducted in Puerto 
Rico, where dengue is endemic and causes severe sporadic epidemics. 
Laboratory positive confirmed cases of dengue, laboratory negative 
suspected dengue cases, and neighborhood controls will be prospectively 
enrolled in the study. Person-to-person interviews with adults (age 18 
years or greater), will be conducted and information will be collected 
regarding symptoms experienced during the convalescent phase of the 
infection. The estimated annualized burden is 400 hours

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                                                                                     Number of     Averge burden
                           Respondents                               Number of     responses per   per response
                                                                    respondents     respondent       (in hrs.)
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Laboratory positive confirmed dengue............................             200               2           20/60
Dengue negative control.........................................             200               2           20/60
Neighborhood control............................................             200               2           20/60
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[[Page 22053]]


    Dated: April 16, 2004.
Bill J. Atkinson,
Acting Director, Management Analysis and Services Office Centers for 
Disease Control And Prevention.
[FR Doc. 04-9234 Filed 4-22-04; 8:45 am]
BILLING CODE 4163-18-P