[Federal Register Volume 69, Number 9 (Wednesday, January 14, 2004)]
[Notices]
[Page 2123]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 04-821]


-----------------------------------------------------------------------

DEPARTMENT OF DEFENSE

Department of the Army


Availability for Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Application Concerning Chemosensitizing Agents 
Against Choroquine Resistant P. Falciparum and Methods of Making and 
Using Thereof

AGENCY: Department of the Army, DoD.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: In accordance with 37 CFR 404.6 and 404.7, announcement is 
made of the availability for licensing of U.S. Patent Application No. 
09/849,400 entitled ``Chemosensitizing Agents Against Chloroquine 
Resistant P. Falciparum and Methods of Making and Using Thereof,'' 
filed May 7, 2001. Foreign rights are also available (PCT/USO1/14574). 
The United States Government, as represented by the Secretary of the 
Army, has rights in this invention.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel, Command, 
ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, 
Frederick, MD 21702-5012.

FOR FURTHER INFORMATION CONTACT: For patent issues, Ms. Elizabeth 
Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul 
Mele, Office of Research & Technology Assessment, (301) 610-6664, both 
at telefax (301) 619-5034.

SUPPLEMENTARY INFORMATION: A compound having the structural formula
[GRAPHIC] [TIFF OMITTED] TN14JA04.002

or pharmaceutically acceptable salt or prodrug thereof, wherein X is a 
substituted or unsubstituted alkyl or a heteroatom; n is 4, 5 or 6; Y 
is a substituted or unsubsituted or alkyl, cycloalkyl, 
heterocycloalkyl, aryl, heteroaryl, or
[GRAPHIC] [TIFF OMITTED] TN14JA04.003

wherein R1 and R2 are each independently, H, a heteroatom, substituted 
or unsubstituted alkyl, cycloalkl, heterocycloalkyl, aryl, or 
heteroaryl; and wherein each ring structure are independently 
substituted or unsubsituted is disclosed. Also disclosed are 
chemosensitizing agents and methods of modulating, attenuating, 
reversing, or affecting a cell's or organism's resistance to a given 
drug such as an antimalarial.

Luz D. Ortiz,
Army Federal Register Liaison Officer.
[FR Doc. 04-821 Filed 1-13-04; 8:45 am]
BILLING CODE 3710-08-M