[Federal Register Volume 68, Number 227 (Tuesday, November 25, 2003)]
[Notices]
[Pages 66114-66117]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 03-29410]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Notice of Listing of Grants for Research Projects

AGENCY: National Institutes of Health, Department of Health and Human 
Services.

ACTION: Notice.

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SUMMARY: Section 52.1(b) of the regulations governing grants for 
research projects, codified at 42 CFR part 52, provides that the 
Secretary of Health and Human Services will periodically publish a list 
of all of the research project grant programs to which the research 
project grant regulations apply. This Notice provides the most recent 
list of the programs covered by the regulations and supersedes and 
replaces the prior Notice published October 24, 1996 (61 FR 55102-
55106).

EFFECTIVE DATE: November 25, 2003.

FOR FURTHER INFORMATION CONTACT: Jerry Moore, NIH Regulations Officer, 
Office of Management Assessment, 6011 Executive Boulevard, Room 601, 
MSC 7669, Rockville, MD 20892, telephone (301) 496-4607 (not a toll-
free number), fax (301) 402-0169, e-mail [email protected].

SUPPLEMENTARY INFORMATION: The National Institutes of Health (NIH) 
published a final rule in the Federal Register on October 24, 1996 (61 
FR 55102-55106), amending the regulations at 42 CFR part 52, Grants for 
Research Projects, which govern Public Health Service (PHS) research 
project grants. The regulations were amended to apply to all research 
project grant programs administered by NIH and the Department of Health 
and Human Services (Department), except for grants for health services 
research, demonstration, and evaluation projects administered by the 
Agency for Health Care Policy and Research (AHCPR), to make it 
unnecessary to include a long list of programs in the regulations or to 
go through the lengthy process of amending the regulations each time a 
new program is established. At that time we provided in the preamble a 
listing of the applicable programs and indicated that we would 
periodically publish a list of the research project grant programs to 
which the regulations apply, and the applicability of the regulations 
to new programs would be announced as Department components initiated 
new programs.
    We are publishing the list of programs to which the regulations 
apply to reflect the addition of new authorities in sections 317J, 
317K, 317L, 330E, 399M, 399N, 409E, 434A, 445I, 447B, and 1261 of the 
Public Health Service Act (PHS Act), as amended. Section 317J of the 
PHS Act (42 U.S.C. 247b-11), as amended by section 601 of the 
Children's Health Act of 2000, Public Law 106-310, concerns research 
with respect to education and training for health professionals and the 
general public relating to the effects of folic acid in preventing 
birth defects. Section 317K of the PHS Act (42 U.S.C. 247b-12), as 
amended by section 901 of Public Law 106-310, concerns research 
relating to risk factors, prevention strategies, and the roles of the 
family, health care providers, and the community in safe motherhood. 
Section 317L of the PHS Act (42 U.S.C.247b-13), as amended by section 
911 of Public Law 106-310, concerns epidemiological research on the 
prevention of prenatal and postnatal smoking, alcohol, and illegal drug 
use. Section 330E of the PHS Act (42 U.S.C. 254c-5), as amended by 
section 801 of Public Law 106-310, concerns research relating to 
intervention strategies to improve the lives of persons with epilepsy, 
particularly children. Section 399M of the PHS Act (42 U.S.C. 280g-1), 
as amended by section 702 of Public Law 106-310, concerns research 
relating to the efficacy of new screening techniques and technology, 
including clinical studies on the efficacy of new interventions, 
regarding hearing loss in infants. Section 399N of the PHS Act (42 
U.S.C. 280g-2), as amended by section 1101 of Public Law 106-310, 
concerns research relating to improving the outcomes among children 
with childhood cancers and resultant secondary conditions. Section 409E 
of the PHS Act (42 U.S.C. 284i), as amended by section 1901 of Public 
Law 106-310, concerns research relating to autoimmune diseases. Section 
434A of the PHS Act (42 U.S.C. 285c-9), as amended by section 402 of 
Public Law 106-310, concerns long-term epidemiology studies relating to 
type 1 or juvenile diabetes. Section 445I of the PHS Act (42 U.S.C. 
285e-10a), as added by section 801 of the Public Health Improvement 
Act, Public Law 106-505, concerns Alzheimer's Disease Clinical Research 
and Training Awards to enhance and promote the translation of new 
scientific knowledge into clinical practice related to the diagnosis, 
care, and treatment of individuals with Alzheimer's disease. Section 
447B of the PHS Act (42 U.S.C. 285f-3), as amended by section 901 the 
Public Health Improvement Act, Public Law 106-505, concerns Sexually 
Transmitted Disease Clinical Research and Training Awards to enhance 
and promote the translation of new scientific knowledge into clinical 
practice related to the diagnosis, care, and treatment of individuals 
with sexually transmitted diseases. Finally, section 1261 of the PHS 
Act (42 U.S.C. 300d-61), as amended by section 1303 of Public Law 106-
310, concerns basic and applied research regarding traumatic brain 
injury, including the development, modification, and evaluation of 
therapies and programs of rehabilitation toward reaching or restoring 
normal capabilities.

[[Page 66115]]

    The regulations codified at 42 CFR part 52 apply to all Public 
Health Service research project grant programs except for grants for 
health services research, demonstration, and evaluation projects 
administered by the AHCPR. Specifically, the research project grant 
authorities to which the Grants for Research Projects regulations apply 
include:
    (1) Research into the cause, diagnosis, treatment, control, or 
prevention of the physical or mental diseases, injuries, or impairments 
to human life, as authorized by sections 301, 302, and related 
provisions of the PHS Act (42 U.S.C. 241, 242);
    (2) Research into the prevention and control of childhood lead 
poising, as authorized under section 301 of the PHS Act (42 U.S.C. 
241);
    (3) Epidemiologic studies, and state-based research capacity 
building projects for the prevention of primary and secondary 
disabilities, as authorized under section 301 of the PHS Act (42 U. S 
C. 241);
    (4) Ecological and epidemiologic research studies in Lyme disease, 
including disease surveillance, development and evaluation of 
prevention and control studies, and development of improved diagnostic 
tests, as authorized under section 301 of the PHS Act (42 U.S.C. 241);
    (5) Research for the development of knowledge and approaches to the 
epidemiology, eitology, diagnosis, treatment, control and prevention of 
narcotic addiction and intravenous (IV)-related AIDS and drug abuse, as 
authorized under sections 301 and 302 of the PHS Act (42 U.S.C. 241, 
242);
    (6) Investigations to identify strategies for prevention of 
childhood deaths from diarrhea, as authorized under sections 301 and 
317(k) of the PHS Act (42 U.S.C. 241, 247b(k));
    (7) HIV/AIDS surveillance, HIV serosurveillance surveys and 
studies, and epidemiologic research studies of AIDS and HIV infection, 
as authorized under sections 301 and 317(k) of the PHS Act (42 U.S.C. 
241, 247b(k));
    (8) Surveillance and epidemiologic studies for the prevention of 
infectious diseases and injuries in children in child day care 
settings, as authorized under sections 310, 317(k), and 391 of the PHS 
Act (42 U.S.C. 241, 247b(k), 280(b));
    (9) Research into prevention and control of tuberculosis, 
especially research concerning strains of tuberculosis resistant to 
drugs and research concerning cases of tuberculosis that affect certain 
populations, as authorized by section 317E of the PHS Act (42 U.S.C. 
247b-6);
    (10) Research with respect to education and training for health 
professionals and the general public relating to the effects of folic 
acid in preventing birth defects, as authorized by section 317J of the 
PHS Act (42 U.S.C. 247b-11);
    (11) Research relating to risk factors, prevention strategies, and 
the roles of the family, health care providers, and the community in 
safe motherhood, as authorized by section 317K of the PHS act, as 
amended by section 901 of Public Law 106-310 (42 U.S.C. 424b-12);
    (12) Epidemiological research on the prevention of prenatal and 
postnatal smoking, alcohol, and illegal drug use, as authorized by 
section 317L of the PHS Act, as amended by section 911 of Public Law 
106-310 (42 U.S.C. 247b-13);
    (13) Research relating to intervention strategies to improve the 
lives of persons with epilepsy, particularly children, as authorized by 
section 330E of the PHS Act (42 U.S.C. 254c-5);
    (14) Injury prevention and control research, as authorized by 
section 391 of the PHS Act (42 U.S.C. 280b);
    (15) Research relating to the efficacy of new screening techniques 
and technology, including clinical studies of screening methods and 
studies on the efficacy of new interventions, regarding hearing loss in 
infants, as authorized by section 399M of the PHS Act, as amended by 
section 702 of Public Law 106-310 (42 U.S.C. 280g-1);
    (16) Research relating to improving the outcomes among children 
with childhood cancers and resultant secondary conditions, as 
authorized by section 399N of the PHS Act, as amended by section 1101 
of Public Law 106-310 (42 U.S.C. 280g-2);
    (17) Research on osteoporosis, Paget's disease and related bone 
disorders, as authorized by section 409A of the PHS Act (42 U.S.C. 
284e);
    (18) Research relating to autoimmune diseases, as authorized by 
section 409E of the PHS Act, as amended by section 1901 of Public Law 
106-310 (42 U.S.C. 284i);
    (19) Long-term epidemiology studies relating to type 1 or juvenile 
diabetes, as authorized by section 434A of the PHS Act, as amended by 
section 402 of Public Law 106-310 (42 U.S.C. 285c-9);
    (20) Biomedical research in areas relating to Alzheimer's disease 
and related dementias, as authorized by section 445B of the PHS Act (42 
U.S.C. 285e-4);
    (21) Clinical research and training to enhance and promote the 
translation of new scientific knowledge into clinical practice related 
to the diagnosis, care and treatment of individuals with Alzheimer's 
disease, as authorized by section 445I of the PHS Act (42 U.S.C. 285e-
10a);
    (22) Clinical research and training to enhance and promote the 
translation of new scientific knowledge into clinical practice related 
to the diagnosis, care, and treatment of individuals with sexually 
transmitted diseases, as authorized by section 447B of the PHS act, as 
amended by section 901 of Public Law 106-505 (42 U.S.C. 285f-3);
    (23) Research relating to medical rehabilitation, as authorized by 
section 452 of the PHS Act (42 U.S.C. 285g-4);
    (24) Research on clinical and health services on eye care and 
diabetes, as authorized by section 456 of the PHS Act (42 U.S.C. 285i-
1);
    (25) Research on multiple sclerosis, especially research on the 
effects of genetics and hormonal changes on the progress of the disease 
, as authorized by section 460 of the PHS Act (42 U.S.C. 285j-3);
    (26) Research on the social, behavioral, and biomedical etiology, 
mental and physical health consequences, and social and economic 
consequences of alcohol abuse and alcoholism, as authorized by 464H of 
the PHS Act (42 U.S.C. 285n);
    (27) Health services research activities with respect to the 
prevention of alcohol abuse and treatment of alcoholism, as authorized 
by section 464H of the PHS Act (42 U.S.C. 285n) and defined in section 
409 of the PHS Act (42 U.S.C. 284d);
    (28) Research under the Medication Development Program to encourage 
and promote the development and use medications to treat drug 
addiction; and to collect, analyze, and disseminate data, as authorized 
by section 464P of the PHS Act (42 U.S.C. 285o-4);
    (29) Research on health related educational technologies, medical 
library science and related activities, and for the development or 
dissemination of new knowledge, techniques, systems, and equipment for 
processing, storing, retrieving, and distributing information 
pertaining to health sciences, as authorized by section 473 of the PHS 
Act (42 U.S.C. 286b-4);
    (30) Research in the biomedical , contraceptive, development, 
behavioral and program implementation fields related to family planning 
and population, as authorized by section 1004 of the PHS Act (42 U.S.C. 
300a-2);
    (31) Basic and applied research regarding traumatic brain injury, 
including the development, modification, and evaluation of

[[Page 66116]]

therapies and programs of rehabilitation toward reaching or restoring 
normal capabilities, as authorized by section 1261 of the PHS Act, as 
amended by section 1301 of Public Law 106-310 (42 U.S.C. 300d-61);
    (32) Research on the causes, consequences and approaches of coping 
with adolescent sexual relations, contraceptive use, pregnancy, and 
parenthood , as authorized by section 2008 of the PHS Act (42 U.S.C. 
300z-7);
    (33) Research relating to the evaluation of drug treatments for 
AIDS not approved by the Commissioner of Food and Drugs, as authorized 
by section 2314 of the PHS Act (42 U.S.C. 300cc-14);
    (34) International research relating to the development and 
evaluation of vaccines and treatments for AIDS, as authorized by 
section 2315 of the PHS Act (42 U.S.C. 300cc-15);
    (35) Long-term research into treatments for AIDS, as authorized by 
section 2320 of the PHS Act (42 U.S.C. 300cc-20);
    (36) Research relating to AIDS conducted outside of the United 
States by qualified foreign professionals and collaborative research 
involving American and foreign participants, as authorized by section 
2354 of the PHS Act (42 U.S.C. 300cc-41);
    (37) Basic research to identify, characterize, and quantify risks 
to human health from air pollutants, as authorized by section 103 of 
the Clean Air Act, as amended (42 U.S.C. 7403);
    (38) Electronic product radiation control research programs 
designed to protect the public health and safety from electronic 
product radiation, as authorized by section 532 of the Federal Food, 
Drug, and Cosmetic Act, as amended (21 U.S.C. 360ii);
    (39) Research into areas where a microgravity environment may 
contribute to significant progress in the understanding and treatment 
of diseases and other medical conditions , as authorized by section 603 
of the National Aeronautics and Space Administration Authorization Act, 
Fiscal Year 1993 (42 U.S.C. 2487b);
    (40) Support for radiation studies and research, as authorized 
under section 301 of the PHS Act (42 U.S.C. 241) and by section 20(a) 
of the Occupational Safety and Health Act of 1970 (29 U.S.C. 669(a));
    (41) Research on occupational safety and health problems in 
industry, as authorized by section 20(a) of the Occupational Safety and 
Health Act of 1970 (29 U.S.C. 669(a)) and section 501 of the Federal 
Coal Mine Health and Safety Act of 1969 (30 U.S.C. 951); and
    (42) Research to stimulate health-related technological innovation, 
especially through the use of small business, minority, and 
disadvantaged firms and increased private sector commercialization of 
innovations derived from federal research and development, as 
authorized under section 301 of the PHS Act (42 U.S.C. 241), in 
accordance with the procedures prescribed pursuant to section 2 [9] of 
the Small Business Innovation Development Act of 1982, as amended (15 
U.S.C. 638).
    The Catalogue of Federal Domestic Assistance (CFDA) numbered 
programs affected by title 42 of the Code of Federal regulations, part 
52, are:

93.113--Biological Response to Environmental Health Hazards
93.114--Applied Toxicological Research and Testing
93.115--Biometry and Risk Estimation'' Health Risks from Environmental 
Exposures
93.118--Acquired Immunodeficiency Syndrome (AIDS) Activity
93.121--Oral Diseases and Disorders Research
93.135--Centers for Research and Demonstration for Health Promotion and 
Disease Prevention
93.136--Injury Control Research Projects
93.154--Special International Postdoctoral Research Program in Acquired 
Immunodeficiency Syndrome (AIDS)
93.172--Human Genome Research
93.173--Biological Research Related to Deafness and Communicative 
Disorders
93.184--Disabilities Prevention
93.198--Biological Models and Materials Resources Program
93.242--Mental Health Research Grants
93.262--Occupational Safety and Health Research Grants
93.271--Alcohol Scientist Development Award; Scientist Development 
Award for Clinicians; and Research Scientist Award
93.172--Human Genome Research
93.273--Alcohol Research Programs
93.277--Drug Abuse Scientist Development Award for Clinicians, and 
Scientist Development Awards
93.279--Drug Abuse Research Programs
93.281--Mental Health Research Scientist Development Award, Research 
Scientist Development Award for Clinicians, and Research Scientist 
Award
93.283--Centers for Disease Control-Investigation and Technical 
Assistance
93.306--Comparative Medicine Program (formerly called Laboratory Animal 
Sciences and Primate Research)
93.333--General Clinical Research Centers
93.361--Nursing Research
93.371--Biomedical Research Technology
93.389--Research Centers in Minority Institutions
93.390--Academic Research Enhancement Award
93.393--Cancer Cause and Prevention Research
93.394--Cancer Detection and Diagnosis Research
93.395--Cancer Treatment Research
93.396--Cancer Biology Research
93.821--Biophysics and Physiological Sciences Research
93.837--Heart and Vascular Diseases Research
93.838--Lung Diseases Research 13
93.839--Blood Diseases and Resources Research
93.846--Arthritis, Musculoskeletal and Skin Diseases Research
93.847--Diabetes, Endochrinology and Metabolic Research
93.848--Digestive Diseases and Nutrition Research
93.849--Kidney Diseases, Urology and Hematology Research
93.853--Clinical Research Related to Neurological Disorders
93.854--Biological Basic Research in the Neurosciences
93.855--Allergy, Immunology, and Transplantation Research
93.856--Microbiology and Infectious Diseases Research
93.859--Pharmacological Sciences
93.862--Genetics Research
93.863--Cellular and Molecular Basis of Disease Research
93.864--Population Research
93.865--Research for Mothers and Children
93.866--Aging Research
93.867--Vision Research
93.879--Medical Library Assistance
93.929--Center for Medical Rehabilitation Research
93.934--Fogarty International Research Collaboration Award
93.939--Blood Diseases and Resources Research
93.941--HIV Demonstration, Research, Public and Professional Education 
Projects
93.942--Research, Treatment and Education Programs on Lyme Disease in 
the United States
93.943--Epidemiologic Research Studies of Acquired Immunodeficiency 
Syndrome (AIDS) and Human Immunodeficiency Virus (HIV) Infection in 
Selected Population Groups
93.947--Tuberculosis Demonstration, Research, Public and Professional 
Education


[[Page 66117]]


    Dated: September 29, 2003.
Elias A. Zerhouni,
Director, National Institutes of Health.
    Approved: November 10, 2003.
Tommy G. Thompson,
Secretary.
[FR Doc. 03-29410 Filed 11-25-03; 8:45 am]
BILLING CODE 4140-01-P