[Federal Register Volume 66, Number 170 (Friday, August 31, 2001)]
[Notices]
[Pages 46020-46021]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 01-21987]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Public Health Service


National Toxicology Program; Meeting of the Advisory Committee on 
Alternative Toxicological Methods

    Pursuant to section 10(a) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of 
the National Toxicology Program (NTP) Advisory Committee on Alternative 
Toxicological Methods, U.S. Public Health Service. The meeting will be 
held from 9:00 a.m. to adjournment on September 25, 2001 in the Rodbell 
Auditorium, Rall Building, South Campus, National Institute of 
Environmental Health Sciences (NIEHS), 111 T.W. Alexander Drive, 
Research Triangle Park, North Carolina. The meeting is open to the 
public and time is allotted during the meeting for the public to 
present comments to the Committee and NTP staff on agenda topics. 
Attendance is limited only by the space available. Individuals who plan 
to attend and need special assistance are asked to notify the Executive 
Secretary in advance of the meeting.

Background

    Under authority of 42 U.S.C. 217a, section 222 of the Public Health 
Service Act, as amended, the Department of Health and Human Services 
has established an Advisory Committee on Alternative Toxicological 
Methods (the Committee). The Committee provides advice to the NTP on 
the activities and priorities of the NTP Interagency Center for the 
Evaluation of Alternative Toxicological Methods (the Center) and the 
Interagency Coordinating Committee on the Validation of Alternative 
Methods (ICCVAM) and on ways to foster partnership activities and 
productive interactions among all stakeholders. The Committee is 
composed of knowledgeable representatives drawn from academia, 
industry, public interest organizations, and may include representation 
from state and federal agencies and the international community, as 
appropriate [Federal Register: September 15, 1997 (Volume 62, Number 
178, Page 48290)].

Agenda

    The September 25th meeting is open to the public from 9:00 AM to 
adjournment with attendance limited only by the space available. A 
draft agenda with tentative schedule is provided below. Primary agenda 
topics

[[Page 46021]]

include updates on recent NTP Center and ICCVAM activities and areas 
for future priorities and activities.
    A detailed agenda with meeting schedule and the Committee roster 
will be available prior to the meeting on the Center's web site (http://iccvam.niehs.nih.gov) or by contacting the NTP Executive Secretary, 
Dr. Mary S. Wolfe (National Toxicology Program, P. O. Box 12233, 111 
T.W. Alexander Drive, A3-07, NIEHS, Research Triangle Park, North 
Carolina 27709, telephone: 919-541-3971 and FAX: 919-541-0295). 
Following the meeting, summary minutes will be posted on the Center's 
web site (http://iccvam.niehs.nih.gov, see ACATM) or can be obtained by 
contacting the Executive Secretary. The minutes for past committee 
meetings are also available on the web.

Public Comment Encouraged

    Public input at the meeting is invited and time is set aside for 
the presentation of public comments on any agenda topic. At least seven 
minutes will be allotted to each speaker, and if time permits, may be 
extended to ten minutes. Persons registering to make oral comments are 
asked to provide their name, affiliation, mailing address, telephone, 
FAX, e-mail, and sponsoring organization (if any). Each organization is 
allowed one time slot per agenda topic. To facilitate planning for the 
meeting, persons interested in providing formal oral comments are asked 
to notify the Executive Secretary at the address given above. Persons 
registering to make oral comments are asked, if possible, to provide a 
copy of their statement to the Executive Secretary by September 19, to 
enable review by the Committee and NTP staff prior to the meeting. 
Individuals will also be able to register to give oral comments on-site 
at the meeting. However, if registering on-site and reading from 
written text, please bring 25 copies of the statement for distribution 
to the Committee and NTP staff and to supplement the record.
    Persons may also submit written comments in lieu of making oral 
comments. Written comments should be sent to the Executive Secretary 
and should be received by September 19, 2001 to enable review by the 
Committee and NTP staff, as well as to supplement the record. Persons 
submitting written comments should include with the document their 
name, affiliation, mailing address, telephone, FAX, e-mail, and 
sponsoring organization (if any).

    Dated: August 23, 2001.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Sciences.

Draft Agenda (8/18/01)--National Toxicology Program Advisory 
Committee on Alternative Toxicological Methods

September 25, 2001

9:00 am--Call to Order and Introductions
Updates
     NTP
     NTP Center and ICCVAM Updates
Guidance Document on Using In Vitro Data to Estimate In Vivo Starting 
Doses for Acute Toxicity (ACTION)
     Public Comments
Report of the International Workshop on In Vitro Methods for Assessing 
Acute Systemic Toxicity
     Public Comments
12:30 pm--Lunch
1:30 pm
Toxicogenomics as An Alternative Toxicological Test Method: Priorities 
for Validation and Applications and Their Validation
     Public Comments
NIEHS Extramural SBIR Contracts for Test Method Development and 
Validation
Other Issues
     International Validation Issues
     Agenda Topics for Next Meeting
     Other Topics
Public Comments
4:30 pm--Adjourn

[FR Doc. 01-21987 Filed 8-30-01; 8:45 am]
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